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Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Circulation research, 2020-01, Vol.126 (3), p.298-314

2020

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Assessing the Validity and Utility of the Guyton Model of Arterial Blood Pressure Control

Hypertension (Dallas, Tex. 1979), 2018-12, Vol.72 (6), p.1272-1273

Beard, Daniel A

2018

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Catalytic Coupling of Oxidative Phosphorylation, ATP Demand, and Reactive Oxygen Species Generation

Biophysical journal, 2016-02, Vol.110 (4), p.962-971

2016

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Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections

Journal of the American Society of Nephrology, 2018-08, Vol.29 (8), p.2081-2088

2018

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A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation

PLoS computational biology, 2005-09, Vol.1 (4), p.e36-e36

2005

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Relationship between thermodynamic driving force and one-way fluxes in reversible processes

PloS one, 2007-01, Vol.2 (1), p.e144-e144

2007

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Minimum Information About a Simulation Experiment (MIASE)

PLoS computational biology, 2011-04, Vol.7 (4), p.e1001122-e1001122

2011

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Hypoxic pulmonary vasoconstriction as a regulator of alveolar-capillary oxygen flux: A computational model of ventilation-perfusion matching

PLoS computational biology, 2021-05, Vol.17 (5), p.e1008861-e1008861

2021

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Computer Modeling of Mitochondrial Tricarboxylic Acid Cycle, Oxidative Phosphorylation, Metabolite Transport, and Electrophysiology

The Journal of biological chemistry, 2007-08, Vol.282 (34), p.24525-24537

2007

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Computational modeling of ventricular-ventricular interactions suggest a role in clinical conditions involving heart failure

Frontiers in physiology, 2023-09, Vol.14, p.1231688-1231688

2023

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Feedback Regulation and Time Hierarchy of Oxidative Phosphorylation in Cardiac Mitochondria

Biophysical journal, 2016-02, Vol.110 (4), p.972-980

2016

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FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans

Nature communications, 2023-02, Vol.14 (1), p.562-562, Article 562

2023

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Analysis of the Kinetics and Bistability of Ubiquinol:Cytochrome c Oxidoreductase

Biophysical journal, 2013-07, Vol.105 (2), p.343-355

2013

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Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture

PloS one, 2018-11, Vol.13 (11), p.e0207803-e0207803

2018

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Analysis of cardiac mitochondrial Na+âCa2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handing suggests a 3: 1 stoichiometry

The Journal of physiology, 2008-07, Vol.586 (13), p.3267-3285

2008

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Determining the origins of superoxide and hydrogen peroxide in the mammalian NADH:ubiquinone oxidoreductase

Free radical biology & medicine, 2014-12, Vol.77, p.121-129

2014

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Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7143-7148

2009

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Determination of the Catalytic Mechanism for Mitochondrial Malate Dehydrogenase

Biophysical journal, 2015-01, Vol.108 (2), p.408-419

2015

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Characterization of Mg2+ Inhibition of Mitochondrial Ca2+ Uptake by a Mechanistic Model of Mitochondrial Ca2+ Uniporter

Biophysical journal, 2011-11, Vol.101 (9), p.2071-2081

2011

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Energy Balance for Analysis of Complex Metabolic Networks

Biophysical journal, 2002-07, Vol.83 (1), p.79-86

2002

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Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts

The Journal of physiology, 2008-09, Vol.586 (17), p.4193-4208

2008

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Characterization of the Kinetics of Cardiac Cytosolic Malate Dehydrogenase and Comparative Analysis of Cytosolic and Mitochondrial Isoforms

Biophysical journal, 2015-01, Vol.108 (2), p.420-430

2015

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Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness

Molecular metabolism (Germany), 2023-10, Vol.76, p.101793-101793, Article 101793

2023

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Arterial stiffening provides sufficient explanation for primary hypertension

PLoS computational biology, 2014-05, Vol.10 (5), p.e1003634-e1003634

2014

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Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Assessing the Validity and Utility of the Guyton Model of Arterial Blood Pressure Control

Catalytic Coupling of Oxidative Phosphorylation, ATP Demand, and Reactive Oxygen Species Generation

Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections

A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation

Relationship between thermodynamic driving force and one-way fluxes in reversible processes

Minimum Information About a Simulation Experiment (MIASE)

Hypoxic pulmonary vasoconstriction as a regulator of alveolar-capillary oxygen flux: A computational model of ventilation-perfusion matching

Computer Modeling of Mitochondrial Tricarboxylic Acid Cycle, Oxidative Phosphorylation, Metabolite Transport, and Electrophysiology

Computational modeling of ventricular-ventricular interactions suggest a role in clinical conditions involving heart failure

Feedback Regulation and Time Hierarchy of Oxidative Phosphorylation in Cardiac Mitochondria

FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans

Analysis of the Kinetics and Bistability of Ubiquinol:Cytochrome c Oxidoreductase

Crops In Silico : Generating Virtual Crops Using an Integrative and Multi-scale Modeling Platform

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture

Analysis of cardiac mitochondrial Na+âCa2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handing suggests a 3: 1 stoichiometry

Determining the origins of superoxide and hydrogen peroxide in the mammalian NADH:ubiquinone oxidoreductase

Experimentally observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism

Determination of the Catalytic Mechanism for Mitochondrial Malate Dehydrogenase

Characterization of Mg2+ Inhibition of Mitochondrial Ca2+ Uptake by a Mechanistic Model of Mitochondrial Ca2+ Uniporter

Energy Balance for Analysis of Complex Metabolic Networks

Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts

Characterization of the Kinetics of Cardiac Cytosolic Malate Dehydrogenase and Comparative Analysis of Cytosolic and Mitochondrial Isoforms

Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness

Arterial stiffening provides sufficient explanation for primary hypertension

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