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Efficient generation, purification, and expansion of CD34+ hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells

Blood, 2012-09, Vol.120 (13), p.e35-e44

2012

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Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency

PloS one, 2012-09, Vol.7 (9), p.e45173-e45173

2012

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Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells

Molecular therapy, 2007-07, Vol.15 (7), p.1356-1365

2007

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Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection

PloS one, 2009-11, Vol.4 (11), p.e7693-e7693

2009

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A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL leads to enhanced cancer cell killing in human glioblastoma models

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (18), p.8783-8790

2007

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Suppressed Catalytic Activity of Base Excision Repair Enzymes on Rotationally Positioned Uracil in Nucleosomes

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7465-7470

2003

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Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment

Molecular therapy. Methods & clinical development, 2021-09, Vol.22, p.350-359

2021

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Survival of the fittest: in vivo selection and stem cell gene therapy

Blood, 2006-03, Vol.107 (5), p.1751-1760

2006

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Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques

PloS one, 2013-02, Vol.8 (2), p.e56268-e56268

2013

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Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells

PLoS medicine, 2006-05, Vol.3 (5), p.e173-e173

2006

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Large animal models for foamy virus vector gene therapy

Viruses, 2012-12, Vol.4 (12), p.3572-3588

2012

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Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs

Molecular therapy, 2011-07, Vol.19 (7), p.1287-1294

2011

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Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.4082-4092

2014

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Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates

The Journal of clinical investigation, 2010-07, Vol.120 (7), p.2345-2354

2010

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Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model

Blood, 2013-07, Vol.122 (2), p.179-187

2013

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Extended survival of glioblastoma patients after chemoprotective HSC gene therapy

Science translational medicine, 2012-05, Vol.4 (133), p.133ra57

2012

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Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells

Protein engineering, design and selection, 2016-12, Vol.29 (12), p.573-582

2016

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VISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

BMC bioinformatics, 2015-07, Vol.16 (1), p.212, Article 212

2015

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Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies

Molecular therapy. Methods & clinical development, 2014-01, Vol.1 (C), p.14055-14055, Article 14055

2014

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Intravenous injection of a foamy virus vector to correct canine SCID-X1

Blood, 2014-06, Vol.123 (23), p.3578-3584

2014

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Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

Blood, 2008-06, Vol.111 (12), p.5537-5543

2008

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High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector

The Journal of clinical investigation, 2008-04, Vol.118 (4), p.1502-1510

2008

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(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

Human gene therapy, 2015-06, Vol.26 (6), p.399

2015

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Cocal-pseudotyped Lentiviral Vectors Resist Inactivation by Human Serum and Efficiently Transduce Primate Hematopoietic Repopulating Cells

Molecular therapy, 2010-04, Vol.18 (4), p.725-733

2010

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Minimal conditioning in Fanconi anemia promotes multi‐lineage marrow engraftment at 10‐fold lower cell doses

The journal of gene medicine, 2018-10, Vol.20 (10-11), p.e3050-n/a

2018

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Efficient generation, purification, and expansion of CD34+ hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells

Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency

Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection

A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL leads to enhanced cancer cell killing in human glioblastoma models

Suppressed Catalytic Activity of Base Excision Repair Enzymes on Rotationally Positioned Uracil in Nucleosomes

Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment

Survival of the fittest: in vivo selection and stem cell gene therapy

Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques

Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells

Large animal models for foamy virus vector gene therapy

Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs

Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients

Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates

Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model

Extended survival of glioblastoma patients after chemoprotective HSC gene therapy

Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells

VISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies

Intravenous injection of a foamy virus vector to correct canine SCID-X1

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector

(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

Cocal-pseudotyped Lentiviral Vectors Resist Inactivation by Human Serum and Efficiently Transduce Primate Hematopoietic Repopulating Cells

Minimal conditioning in Fanconi anemia promotes multi‐lineage marrow engraftment at 10‐fold lower cell doses

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