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Epigenetic dynamic during endochondral ossification and articular cartilage development

Bone (New York, N.Y.), 2019-03, Vol.120, p.523-532

2019

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Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Laboratory investigation, 2020-01, Vol.100 (1), p.64-71

2020

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Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments

Stem Cells International, 2015-01, Vol.2015 (2015), p.785-798-070

2015

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3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells

PloS one, 2014-05, Vol.9 (5), p.e98176-e98176

2014

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Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation

Nature communications, 2015-09, Vol.6 (1), p.8152-8152, Article 8152

2015

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Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

Biomaterials, 2012-09, Vol.33 (26), p.6042-6051

2012

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Modulation of Skin Inflammatory Response by Active Components of Silymarin

Molecules (Basel, Switzerland), 2019-01, Vol.24 (1), p.123

2019

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Genetic Determinism of Primary Early-Onset Osteoarthritis

Trends in molecular medicine, 2016-01, Vol.22 (1), p.38-52

2016

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Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes

Scientific reports, 2017-07, Vol.7 (1), p.6483-9, Article 6483

2017

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Hypoxia Differentially Affects Chondrogenic Differentiation of Progenitor Cells from Different Origins

International Journal of Stem Cells, 2023-08, Vol.16 (3), p.304-314

2023

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Hypoxia inducible factor 1 alpha down‐regulates type i collagen through Sp3 transcription factor in human chondrocytes

IUBMB life, 2016-09, Vol.68 (9), p.756-763

2016

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Co-Treatment with the Epigenetic Drug, 3-Deazaneplanocin A (DZNep) and Cisplatin after DZNep Priming Enhances the Response to Platinum-Based Therapy in Chondrosarcomas

Cancers, 2021-09, Vol.13 (18), p.4648

2021

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Antiproliferative effect of the histone demethylase inhibitor GSK‐J4 in chondrosarcomas

IUBMB life, 2019-11, Vol.71 (11), p.1711-1719

2019

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The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

BMC complementary medicine and therapies, 2021-10, Vol.21 (1), p.261-261, Article 261

2021

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Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

BMC cancer, 2017-07, Vol.17 (1), p.490-490, Article 490

2017

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Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Arthritis research & therapy, 2011-02, Vol.13 (1), p.R23-R23, Article R23

2011

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Heterogeneity of chondrosarcomas response to irradiations with X-rays and carbon ions: A comparative study on five cell lines

Journal of bone oncology, 2020-06, Vol.22, p.100283-100283, Article 100283

2020

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Description of Joint Alterations Observed in a Family Carrying p.Asn453Ser COMP Variant: Clinical Phenotypes, In Silico Prediction of Functional Impact on COMP Protein and Stability, and Review of the Literature

Biomolecules (Basel, Switzerland), 2021-10, Vol.11 (10), p.1460

2021

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Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism

Connective tissue research, 2008-01, Vol.49 (3), p.293-297

2008

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Asporin expression is highly regulated in human chondrocytes

Molecular medicine (Cambridge, Mass.), 2011-07, Vol.17 (7-8), p.816-823

2011

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Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes

Biochimica et biophysica acta, 2012-05, Vol.1823 (5), p.983-986

2012

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Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia

Tissue engineering. Part C, Methods, 2013-07, Vol.19 (7), p.550-567

2013

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Histone methylases as novel drug targets: developing inhibitors of EZH2

Future medicinal chemistry, 2014-01, Vol.6 (17), p.1943-1965

2014

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Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints

Aging and disease, 2014-12, Vol.5 (6), p.394-405

2014

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EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis

Scientific reports, 2020-11, Vol.10 (1), p.19577-19577, Article 19577

2020

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Epigenetic dynamic during endochondral ossification and articular cartilage development

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments

3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

Modulation of Skin Inflammatory Response by Active Components of Silymarin

Genetic Determinism of Primary Early-Onset Osteoarthritis

Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes

Hypoxia Differentially Affects Chondrogenic Differentiation of Progenitor Cells from Different Origins

Hypoxia inducible factor 1 alpha down‐regulates type i collagen through Sp3 transcription factor in human chondrocytes

Co-Treatment with the Epigenetic Drug, 3-Deazaneplanocin A (DZNep) and Cisplatin after DZNep Priming Enhances the Response to Platinum-Based Therapy in Chondrosarcomas

Antiproliferative effect of the histone demethylase inhibitor GSK‐J4 in chondrosarcomas

The benefit of combining curcumin, bromelain and harpagophytum to reduce inflammation in osteoarthritic synovial cells

Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Heterogeneity of chondrosarcomas response to irradiations with X-rays and carbon ions: A comparative study on five cell lines

Description of Joint Alterations Observed in a Family Carrying p.Asn453Ser COMP Variant: Clinical Phenotypes, In Silico Prediction of Functional Impact on COMP Protein and Stability, and Review of the Literature

Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism

Asporin expression is highly regulated in human chondrocytes

Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes

Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia

Histone methylases as novel drug targets: developing inhibitors of EZH2

Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints

EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis

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