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A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6209), p.638-641

2014

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New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1492-1500

2016

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Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs

ACS chemical biology, 2016-08, Vol.11 (8), p.2265-2274

2016

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Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans

International Journal of Obesity, 2016-08, Vol.40 (8), p.1260-1267

2016

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Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

Journal of medicinal chemistry, 2012-02, Vol.55 (4), p.1731-1750

2012

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Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors

ACS infectious diseases, 2017-02, Vol.3 (2), p.152-161

2017

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Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy

Frontiers in oncology, 2020-08, Vol.10, p.1460-1460

2020

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Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition

Chemical science (Cambridge), 2018-03, Vol.9 (9), p.2452-2468

2018

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Monte Carlo advances and concentrated solar applications

Solar energy, 2014-05, Vol.103, p.653-681

2014

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Future of bariatric surgery beyond simple weight loss: Metabolic surgery

Journal of visceral surgery, 2023-04, Vol.160 (2), p.S55-S62

2023

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Islet Survival and Function Following Intramuscular Autotransplantation in the Minipig

American journal of transplantation, 2013-04, Vol.13 (4), p.891-898

2013

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Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?

ACS medicinal chemistry letters, 2014-01, Vol.5 (1), p.23-28

2014

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Endocrine surgery during and after the COVID-19 epidemic: Expert guidelines from AFCE

Journal of visceral surgery, 2020-06, Vol.157 (3), p.S43-S49

2020

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Biophysical Survey of Small-Molecule β‑Catenin Inhibitors: A Cautionary Tale

Journal of medicinal chemistry, 2022-05, Vol.65 (10), p.7246-7261

2022

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Roux-en-Y gastric bypass increases systemic but not portal bile acid concentrations by decreasing hepatic bile acid uptake in minipigs

International Journal of Obesity, 2017-04, Vol.41 (4), p.664-668

2017

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Motor commands induce time compression for tactile stimuli

The Journal of neuroscience, 2014-07, Vol.34 (27), p.9164-9172

2014

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Current strategies for the design of PROTAC linkers: a critical review

Exploration of targeted anti-tumor therapy, 2020-10, Vol.1 (5), p.273-312

2020

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Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors

Beilstein journal of organic chemistry, 2013-01, Vol.9 (1), p.81-88

2013

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Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

European journal of medicinal chemistry, 2018-05, Vol.152, p.101-114

2018

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Structural and optical properties of sputtered ZnO films

Thin solid films, 1999-07, Vol.348 (1-2), p.165-172

1999

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Visuo-tactile shape perception in women with Anorexia Nervosa and healthy women with and without body concerns

Neuropsychologia, 2020-12, Vol.149, p.107635-107635, Article 107635

2020

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Ring‐Expansion Approach to Medium‐Sized Lactams and Analysis of Their Medicinal Lead‐Like Properties

Chemistry : a European journal, 2017-02, Vol.23 (9), p.2225-2230

2017

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Dual wavelength asymmetric photochemical synthesis with circularly polarized light

Chemical science (Cambridge), 2015-07, Vol.6 (7), p.3853-3862

2015

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Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant p53

Structure (London), 2015-12, Vol.23 (12), p.2246-2255

2015

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CA-196: Le gastric bypass ralentit la progression au long cours du DT2 après sa rémission initiale

Diabetes & metabolism, 2016-03, Vol.42, p.A89-A89

2016

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A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition

Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs

Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans

Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

Toward Photopharmacological Antimicrobial Chemotherapy Using Photoswitchable Amidohydrolase Inhibitors

Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy

Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition

Monte Carlo advances and concentrated solar applications

Future of bariatric surgery beyond simple weight loss: Metabolic surgery

Islet Survival and Function Following Intramuscular Autotransplantation in the Minipig

Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?

Endocrine surgery during and after the COVID-19 epidemic: Expert guidelines from AFCE

Biophysical Survey of Small-Molecule β‑Catenin Inhibitors: A Cautionary Tale

Roux-en-Y gastric bypass increases systemic but not portal bile acid concentrations by decreasing hepatic bile acid uptake in minipigs

Motor commands induce time compression for tactile stimuli

Current strategies for the design of PROTAC linkers: a critical review

Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors

Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

Structural and optical properties of sputtered ZnO films

Visuo-tactile shape perception in women with Anorexia Nervosa and healthy women with and without body concerns

Ring‐Expansion Approach to Medium‐Sized Lactams and Analysis of Their Medicinal Lead‐Like Properties

Dual wavelength asymmetric photochemical synthesis with circularly polarized light

Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant p53

CA-196: Le gastric bypass ralentit la progression au long cours du DT2 après sa rémission initiale

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