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The Aminopalladation/Reductive Elimination Domino Reaction in the Construction of Functionalized Indole Rings

European journal of organic chemistry, 2002-08, Vol.2002 (16), p.2671-2681

2002

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Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors

Bioorganic & medicinal chemistry, 2019-08, Vol.27 (15), p.3248-3253

2019

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Synthesis of ST7612AA1, a Novel Oral HDAC Inhibitor, via Radical Thioacetic Acid Addition

Current bioactive compounds, 2016-12, Vol.12 (4), p.282-288

2016

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An Efficient Palladium-Catalyzed Synthesis of Cinnamaldehydes from Acrolein Diethyl Acetal and Aryl Iodides and Bromides

Organic letters, 2003-03, Vol.5 (5), p.777-780

2003

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New classes of potent heparanase inhibitors from ligand-based virtual screening

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.1685-1696

2020

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ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1

Frontiers in oncology, 2020-01, Vol.9, p.1534-1534

2020

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Immunogenicity of COVID-eVax Delivered by Electroporation Is Moderately Impacted by Temperature and Molecular Isoforms

Vaccines (Basel), 2023-03, Vol.11 (3), p.678

2023

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4-Aryl-2-quinolones through a Pseudo-Domino Heck/Buchwald-Hartwig Reaction in a Molten Tetrabutylammonium Acetate/ Tetrabutylammonium Bromide Mixture

Advanced synthesis & catalysis, 2007-02, Vol.349 (3), p.297-302

2007

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Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.462-465

2015

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The Control of Heparanase Through the Use of Small Molecules

Heparanase, p.567-603

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Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (3), p.459-461

2015

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A Molten n-Bu4NOAc/n-Bu4NBr Mixture as an Efficient Medium for the Stereoselective Synthesis of (E)- and (Z)-3,3-Diarylacrylates

Synlett, 2002, Vol.2002 (3), p.439-442

2002

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Epoxidation of chromones and flavonoids in ionic liquids

Tetrahedron, 2004-01, Vol.60 (4), p.967-971

2004

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Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

Molecular therapy, 2022-05, Vol.30 (5), p.1979-1993

2022

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Abstract 4727: ST7612AA1: focus on a drug candidate, front-runner of a new generation of HDAC inhibitors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4727-4727

2016

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Antibody drug conjugates with hydroxamic acid cargos for histone deacetylase (HDAC) inhibition

Chemical communications (Cambridge, England), 2021-01, Vol.57 (7), p.867-87

2021

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Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation

Chemical science (Cambridge), 2018-08, Vol.9 (31), p.6490-6496

2018

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Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6918-6936

2018

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Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

Molecular therapy, 2023-02, Vol.31 (2), p.362-373

2023

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Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.61-64

2014

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Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10834-10859

2018

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ST7612AA1, a Thioacetate-ω(γ-lactam carboxamide) Derivative Selected from a Novel Generation of Oral HDAC Inhibitors

Journal of medicinal chemistry, 2014-10, Vol.57 (20), p.8358-8377

2014

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Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulationElectronic supplementary information (ESI) available: Experimental procedures, biological activity data, NMR spectra for characterisation. See DOI: 10.1039/c7sc05266a

2018-08

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Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation† †Electronic supplementary information (ESI) available: Experimental procedures, biological activity data, NMR spectra for characterisation. See DOI: 10.1039/c7sc05266a

Chemical science (Cambridge), 2018-07, Vol.9 (31), p.6490-6496

2018

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Non-Natural Macrocyclic Inhibitors of Histone Deacetylases: Design, Synthesis, and Activity

Journal of medicinal chemistry, 2010-12, Vol.53 (23), p.8387-8399

2010

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The Aminopalladation/Reductive Elimination Domino Reaction in the Construction of Functionalized Indole Rings

Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors

Synthesis of ST7612AA1, a Novel Oral HDAC Inhibitor, via Radical Thioacetic Acid Addition

An Efficient Palladium-Catalyzed Synthesis of Cinnamaldehydes from Acrolein Diethyl Acetal and Aryl Iodides and Bromides

New classes of potent heparanase inhibitors from ligand-based virtual screening

ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1

Immunogenicity of COVID-eVax Delivered by Electroporation Is Moderately Impacted by Temperature and Molecular Isoforms

4-Aryl-2-quinolones through a Pseudo-Domino Heck/Buchwald-Hartwig Reaction in a Molten Tetrabutylammonium Acetate/ Tetrabutylammonium Bromide Mixture

Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites

The Control of Heparanase Through the Use of Small Molecules

Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite

A Molten n-Bu4NOAc/n-Bu4NBr Mixture as an Efficient Medium for the Stereoselective Synthesis of (E)- and (Z)-3,3-Diarylacrylates

Epoxidation of chromones and flavonoids in ionic liquids

Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

Abstract 4727: ST7612AA1: focus on a drug candidate, front-runner of a new generation of HDAC inhibitors

Antibody drug conjugates with hydroxamic acid cargos for histone deacetylase (HDAC) inhibition

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors

Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity

ST7612AA1, a Thioacetate-ω(γ-lactam carboxamide) Derivative Selected from a Novel Generation of Oral HDAC Inhibitors

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulationElectronic supplementary information (ESI) available: Experimental procedures, biological activity data, NMR spectra for characterisation. See DOI: 10.1039/c7sc05266a

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation† †Electronic supplementary information (ESI) available: Experimental procedures, biological activity data, NMR spectra for characterisation. See DOI: 10.1039/c7sc05266a

Non-Natural Macrocyclic Inhibitors of Histone Deacetylases: Design, Synthesis, and Activity

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