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Non-invasive assessment of telomere maintenance mechanisms in brain tumors

Nature communications, 2021-01, Vol.12 (1), p.92-92, Article 92

2021

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Hyperpolarized δ-[1- 13 C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

Scientific reports, 2023-03, Vol.13 (1), p.5190-5190, Article 5190

2023

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In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1- 13 C]glycine

Scientific reports, 2020-04, Vol.10 (1), p.6244-6244, Article 6244

2020

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In vivo investigation of hyperpolarized [1,3- 13 C 2 ]acetoacetate as a metabolic probe in normal brain and in glioma

Scientific reports, 2019-03, Vol.9 (1), p.3402-3402, Article 3402

2019

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Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1- 13 C]gluconolactone

Frontiers in oncology, 2021-04, Vol.11, p.589570-589570

2021

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IMG-31. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Suppl 4), p.0-0

2024

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DIPG-90. NON-INVASIVE METABOLIC IMAGING OF DIFFUSE MIDLINE GLIOMAS AND THEIR RESPONSE TO THERAPY

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Suppl 4), p.0-0

2024

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EXTH-13. COMBINED TARGETING OF TELOMERASE REVERSE TRANSCRIPTASE AND METABOLISM ABROGATES GLIOBLASTOMA PROLIFERATION IN VIVO

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii211-vii212

2022

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NIMG-68. IMAGING PHOSPHOLIPID BIOSYNTHESIS ENABLES NON-INVASIVE ASSESSMENT OF BRAIN TUMOR RESPONSE TO THERAPY

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii180-vii180

2022

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TMET-20. TERT ACTS VIA FOXO1 TO ALTER REDOX METABOLISM IN BRAIN TUMORS

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii265-vii266

2022

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Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer

Clinical cancer research, 2022-08, Vol.28 (16), p.3526-3536

2022

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IMG-16. Non-invasive metabolic imaging of response to therapy in diffuse midline gliomas

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i80-i80

2022

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Multi-echo single-shot EPI for hyperpolarized 13C cardiac metabolic imaging of small animals

Journal of cardiovascular magnetic resonance, 2013-01, Vol.15 (Suppl 1), p.P217-P217, Article P217

2013

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TAMI-40. PEDIATRIC H3K27M MUTANT GLIOMAS UNDERGO METABOLIC REPROGRAMMING THAT CAN BE LEVERAGED FOR NON-INVASIVE METABOLIC IMAGING

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (Supplement_6), p.vi206-vi207

2021

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NIMG-51. DEUTERIUM METABOLIC IMAGING OF BRAIN TUMOR IMMORTALITY USING 2H-PYRUVATE

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (Supplement_6), p.vi140-vi141

2021

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BIOM-10. PRECLINICAL PLATFORM FOR THE IDENTIFICATION OF DEUTERIUM MAGNETIC RESONANCE SPECTROSCOPY-BASED BIOMARKERS OF BRAIN TUMOR METABOLISM

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (Supplement_6), p.vi12-vi12

2021

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Acquisition and quantification pipeline for in vivo hyperpolarized 13C magnetic resonance spectroscopy

Magnetic resonance in medicine, 2021-11, Vol.87 (4), p.1673-1687

2021

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TMET-12. HYPERPOLARIZED Δ- [1-13C] GLUCONOLACTONE IMAGING VISUALIZES TERT-ASSOCIATED CHANGES IN DYNAMIC PENTOSE PHOSPHATE PATHWAY METABOLISM IN GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii264-vii264

2022

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PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival

Scientific reports, 2019-07, Vol.9 (1), p.10521-15, Article 10521

2019

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Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy

Magnetic resonance in medicine, 2022-04, Vol.87 (4), p.1673-1687

2022

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Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy

Magnetic resonance in medicine, 2022-04, Vol.87 (4), p.1673-1687

2022

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TAMI-08. A TALE OF TWO TELOMERE MAINTENANCE MECHANISMS: TERT EXPRESSION AND THE ALT PATHWAY INDUCE UNIQUE MRS-DETECTABLE METABOLIC REPROGRAMMING IN LOW-GRADE GLIOMAS

Neuro-oncology (Charlottesville, Va.), 2020-11, Vol.22 (Supplement_2), p.ii214-ii214

2020

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Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone

Neuro-oncology advances, 2023-01, Vol.5 (1), p.vdad092-vdad092

2023

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EXTH-46. MRS BASED BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO THE IDH INHIBITOR BAY-1436032

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (Supplement_6), p.vi173-vi173

2021

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BIOM-14. METABOLIC BIOMARKERS OF TERT-TARGETED THERAPY FOR HUMAN GLIOBLASTOMA DETECTED BY MAGNETIC RESONANCE SPECTROSCOPY

Neuro-oncology (Charlottesville, Va.), 2021-11, Vol.23 (Supplement_6), p.vi13-vi13

2021

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Non-invasive assessment of telomere maintenance mechanisms in brain tumors

Hyperpolarized δ-[1- 13 C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1- 13 C]glycine

In vivo investigation of hyperpolarized [1,3- 13 C 2 ]acetoacetate as a metabolic probe in normal brain and in glioma

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1- 13 C]gluconolactone

IMG-31. DEUTERIUM METABOLIC IMAGING OF RESPONSE TO PRECISION THERAPY IN BRAF-V600E MUTANT GLIOMAS

DIPG-90. NON-INVASIVE METABOLIC IMAGING OF DIFFUSE MIDLINE GLIOMAS AND THEIR RESPONSE TO THERAPY

EXTH-13. COMBINED TARGETING OF TELOMERASE REVERSE TRANSCRIPTASE AND METABOLISM ABROGATES GLIOBLASTOMA PROLIFERATION IN VIVO

NIMG-68. IMAGING PHOSPHOLIPID BIOSYNTHESIS ENABLES NON-INVASIVE ASSESSMENT OF BRAIN TUMOR RESPONSE TO THERAPY

TMET-20. TERT ACTS VIA FOXO1 TO ALTER REDOX METABOLISM IN BRAIN TUMORS

Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer

IMG-16. Non-invasive metabolic imaging of response to therapy in diffuse midline gliomas

Multi-echo single-shot EPI for hyperpolarized 13C cardiac metabolic imaging of small animals

TAMI-40. PEDIATRIC H3K27M MUTANT GLIOMAS UNDERGO METABOLIC REPROGRAMMING THAT CAN BE LEVERAGED FOR NON-INVASIVE METABOLIC IMAGING

NIMG-51. DEUTERIUM METABOLIC IMAGING OF BRAIN TUMOR IMMORTALITY USING 2H-PYRUVATE

BIOM-10. PRECLINICAL PLATFORM FOR THE IDENTIFICATION OF DEUTERIUM MAGNETIC RESONANCE SPECTROSCOPY-BASED BIOMARKERS OF BRAIN TUMOR METABOLISM

Acquisition and quantification pipeline for in vivo hyperpolarized 13C magnetic resonance spectroscopy

TMET-12. HYPERPOLARIZED Δ- [1-13C] GLUCONOLACTONE IMAGING VISUALIZES TERT-ASSOCIATED CHANGES IN DYNAMIC PENTOSE PHOSPHATE PATHWAY METABOLISM IN GLIOBLASTOMA

PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival

Acquisition and quantification pipeline for in vivo hyperpolarized 13 C MR spectroscopy

Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy

TAMI-08. A TALE OF TWO TELOMERE MAINTENANCE MECHANISMS: TERT EXPRESSION AND THE ALT PATHWAY INDUCE UNIQUE MRS-DETECTABLE METABOLIC REPROGRAMMING IN LOW-GRADE GLIOMAS

Imaging telomerase reverse transcriptase expression in oligodendrogliomas using hyperpolarized δ-[1-13C]-gluconolactone

EXTH-46. MRS BASED BIOMARKERS OF IDH1 MUTANT GLIOMA RESPONSE TO THE IDH INHIBITOR BAY-1436032

BIOM-14. METABOLIC BIOMARKERS OF TERT-TARGETED THERAPY FOR HUMAN GLIOBLASTOMA DETECTED BY MAGNETIC RESONANCE SPECTROSCOPY

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