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Oxidants, antioxidants and the ischemic brain

Journal of experimental biology, 2004-08, Vol.207 (Pt 18), p.3221-3231

2004

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Manganese Porphyrin, MnTE-2-PyP5+, Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells

Free radical biology & medicine, 2012-04, Vol.52 (8), p.1272-1284

2012

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Thiol regulation by Mn porphyrins, commonly known as SOD mimics

Redox biology, 2019-07, Vol.25, p.101139-101139, Article 101139

2019

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A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon

Anti-cancer agents in medicinal chemistry, 2011-05, Vol.11 (4), p.329

2011

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An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

Redox biology, 2015-08, Vol.5, p.43-65

2015

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Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential

Antioxidants & redox signaling, 2010-09, Vol.13 (6), p.877

2010

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Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Journal of the American Heart Association, 2018-10, Vol.7 (20)

2018

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Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

Frontiers in microbiology, 2018-07, Vol.9, p.1699-1699

2018

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Cardioprotective effects of redox regulator MnTnBuOE‐2‐PyP 5+ in myocardial ischemia/reperfusion injury

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury

International journal of radiation oncology, biology, physics, 2007-02, Vol.67 (2), p.573-580

2007

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Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36579-36588

2013

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UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

The Journal of biological chemistry, 2019-04, Vol.294 (17), p.6831-6842

2019

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Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints

Food and chemical toxicology, 2016-01, Vol.87, p.65-76

2016

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Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes

Redox report : communications in free radical research, 2021-01, Vol.26 (1), p.85-93

2021

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Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System

Antioxidants & redox signaling, 2017-09, Vol.27 (9), p.534

2017

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Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

Free radical biology & medicine, 2011-09, Vol.51 (5), p.1035-1053

2011

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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

Free radical biology & medicine, 2015-09, Vol.86, p.308-321

2015

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Antibacterial Activity of Synthetic Cationic Iron Porphyrins

Antioxidants, 2020-10, Vol.9 (10), p.972

2020

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NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20477-20482

2010

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Post-illumination cellular effects of photodynamic treatment

PloS one, 2017-12, Vol.12 (12), p.e0188535

2017

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Ortho Isomeric Mn(III) N-Alkyl- and Alkoxyalkylpyridylporphyrins—Enhancers of Hyaluronan Degradation Induced by Ascorbate and Cupric Ions

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8608

2021

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Rotenone-Induced 4-HNE Aggresome Formation and Degradation in HL-1 Cardiomyocytes: Role of Autophagy Flux

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4675

2022

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Mn(III) Porphyrin, MnTnBuOE-2-PyP5+, Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6159

2023

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MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management

Redox biology, 2019-01, Vol.20, p.307-320

2019

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Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

PloS one, 2018-01, Vol.13 (1), p.e0191402-e0191402

2018

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Oxidants, antioxidants and the ischemic brain

Manganese Porphyrin, MnTE-2-PyP5+, Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells

Thiol regulation by Mn porphyrins, commonly known as SOD mimics

A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon

An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins--From superoxide dismutation to H2O2-driven pathways

Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potential

Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

Cardioprotective effects of redox regulator MnTnBuOE‐2‐PyP 5+ in myocardial ischemia/reperfusion injury

Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury

Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints

Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes

Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics

Antibacterial Activity of Synthetic Cationic Iron Porphyrins

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

Post-illumination cellular effects of photodynamic treatment

Ortho Isomeric Mn(III) N-Alkyl- and Alkoxyalkylpyridylporphyrins—Enhancers of Hyaluronan Degradation Induced by Ascorbate and Cupric Ions

Rotenone-Induced 4-HNE Aggresome Formation and Degradation in HL-1 Cardiomyocytes: Role of Autophagy Flux

Mn(III) Porphyrin, MnTnBuOE-2-PyP5+, Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress

MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management

Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

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