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Multimetallic Pd- and Ni-catalyzed C(sp)-P cross-coupling under aqueous micellar conditions

Green chemistry : an international journal and green chemistry resource : GC, 2023-11, Vol.25 (23), p.9779-9794

2023

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Phosphate-Based Self-Immolative Linkers for the Delivery of Amine-Containing Drugs

Molecules (Basel, Switzerland), 2021-08, Vol.26 (17), p.5160

2021

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Medicinal Chemistry of Fluorinated Cyclic and Acyclic Nucleoside Phosphonates

Medicinal research reviews, 2013-11, Vol.33 (6), p.1304-1344

2013

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Design and Synthesis of Novel HIV‑1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.1761-1777

2023

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Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties

Journal of medicinal chemistry, 2021-11, Vol.64 (22), p.16425-16449

2021

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Synthesis of Terminal Ribose Analogues of Adenosine 5′-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2

Journal of organic chemistry, 2019-05, Vol.84 (10), p.6143-6157

2019

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NMR Structure Elucidation of Naphthoquinones from Quambalaria cyanescens

Journal of natural products (Washington, D.C.), 2021-01, Vol.84 (1), p.46-55

2021

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Sterically‐Controlled Self‐Immolation in Phosphoramidate Linkers Triggered by Light

European journal of organic chemistry, 2020-02, Vol.2020 (7), p.897-906

2020

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Helicobacter pylori Xanthine–Guanine–Hypoxanthine PhosphoribosyltransferaseA Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5710-5729

2021

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Reactive cyclic intermediates in the ProTide prodrugs activation: trapping the elusive pentavalent phosphorane

Organic & biomolecular chemistry, 2019-01, Vol.17 (2), p.315-320

2019

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Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

Journal of medicinal chemistry, 2023-05, Vol.66 (10), p.6652-6681

2023

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Extending molecular dynamics with dipolar NMR tensors as constraints to chiral phosphorus compounds

Physical chemistry chemical physics : PCCP, 2024-08, Vol.26 (31), p.20814-20819

2024

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Phosphate‐Based Self‐Immolative Linkers for Tuneable Double Cargo Release

Chemistry : a European journal, 2021-09, Vol.27 (50), p.12763-12775

2021

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Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E 2 Production

Organic process research & development, 2020-09, Vol.24 (9), p.1718-1724

2020

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Phosphate‐Based Self‐Immolative Linkers for Tuneable Double Cargo Release

Chemistry : a European journal, 2021-09, Vol.27 (50), p.12713-12713

2021

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Phosphate linkers with traceable cyclic intermediates for self-immolation detection and monitoring

Chemical communications (Cambridge, England), 2021-01, Vol.57 (2), p.211-214

2021

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Piperazine‐Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens

ChemMedChem, 2022-11, Vol.17 (21), p.e202200385-n/a

2022

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Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers

European journal of medicinal chemistry reports, 2024-12, Vol.12, p.100216, Article 100216

2024

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Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1

European journal of medicinal chemistry, 2016-10, Vol.122, p.185-195

2016

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Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors

Antiviral chemistry & chemotherapy, 2019-01, Vol.27, p.2040206619826265-2040206619826265

2019

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Synthesis of phosphonoacetate analogues of the second messenger adenosine 5′-diphosphate ribose (ADPR)

RSC advances, 2020, Vol.1 (3), p.1776-1785

2020

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Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

Antiviral chemistry & chemotherapy, 2018, Vol.26, p.2040206618813050-2040206618813050

2018

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Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine and a Five‐Membered Heterocycle as Selective Inhibitors of Plasmodial 6‐Oxopurine Phosphoribosyltransferases

ChemMedChem, 2017-07, Vol.12 (14), p.1133-1141

2017

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Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine–guanine–(xanthine) phosphoribosyltransferases

Bioorganic & medicinal chemistry, 2012-01, Vol.20 (2), p.1076-1089

2012

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Variability in the Responses of Hepatitis B Virus D-Subgenotypes to Antiviral Therapy: Designing Pan-D-Subgenotypic Reverse Transcriptase Inhibitors

Journal of virology, 2022-01, Vol.96 (2), p.e0180021-e0180021

2022

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Multimetallic Pd- and Ni-catalyzed C(sp)-P cross-coupling under aqueous micellar conditions

Phosphate-Based Self-Immolative Linkers for the Delivery of Amine-Containing Drugs

Medicinal Chemistry of Fluorinated Cyclic and Acyclic Nucleoside Phosphonates

Design and Synthesis of Novel HIV‑1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties

Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties

Synthesis of Terminal Ribose Analogues of Adenosine 5′-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2

NMR Structure Elucidation of Naphthoquinones from Quambalaria cyanescens

Sterically‐Controlled Self‐Immolation in Phosphoramidate Linkers Triggered by Light

Helicobacter pylori Xanthine–Guanine–Hypoxanthine PhosphoribosyltransferaseA Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Reactive cyclic intermediates in the ProTide prodrugs activation: trapping the elusive pentavalent phosphorane

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors

Extending molecular dynamics with dipolar NMR tensors as constraints to chiral phosphorus compounds

Phosphate‐Based Self‐Immolative Linkers for Tuneable Double Cargo Release

Development of Scalable Synthesis of 5-Butyl-4-(4-methoxyphenyl)-6-phenylpyrimidin-2-amine (WQE-134), a Dual Inhibitor of Nitric Oxide and Prostaglandin E 2 Production

Phosphate‐Based Self‐Immolative Linkers for Tuneable Double Cargo Release

Phosphate linkers with traceable cyclic intermediates for self-immolation detection and monitoring

Piperazine‐Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens

Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers

Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1

Synthesis and anti-human immunodeficiency virus activity of substituted (o,o-difluorophenyl)-linked-pyrimidines as potent non‐nucleoside reverse transcriptase inhibitors

Synthesis of phosphonoacetate analogues of the second messenger adenosine 5′-diphosphate ribose (ADPR)

Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine and a Five‐Membered Heterocycle as Selective Inhibitors of Plasmodial 6‐Oxopurine Phosphoribosyltransferases

Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine–guanine–(xanthine) phosphoribosyltransferases

Variability in the Responses of Hepatitis B Virus D-Subgenotypes to Antiviral Therapy: Designing Pan-D-Subgenotypic Reverse Transcriptase Inhibitors

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