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Evaluation of drug‐induced QT interval prolongation in animal and human studies: a literature review of concordance

British journal of pharmacology, 2015-08, Vol.172 (16), p.4002-4011

2015

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ILSI-HESI cardiovascular safety subcommittee initiative: Evaluation of three non-clinical models of QT prolongation

Journal of pharmacological and toxicological methods, 2006-09, Vol.54 (2), p.116-129

2006

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Response of safety pharmacologists to challenges arising from the rapidly evolving changes in the pharmaceutical industry

Journal of pharmacological and toxicological methods, 2019-07, Vol.98, p.106593-106593, Article 106593

2019

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Is there a role for the no observed adverse effect level in safety pharmacology?

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106917, Article 106917

2020

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A Historical View and Vision into the Future of the Field of Safety Pharmacology

Handbook of experimental pharmacology, 2015, Vol.229, p.3

2015

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Benchmarking Safety Pharmacology regulatory packages and best practice

Journal of pharmacological and toxicological methods, 2008-09, Vol.58 (2), p.99-109

2008

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Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Journal of pharmacological and toxicological methods, 2008-09, Vol.58 (2), p.72-76

2008

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Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1)

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.791-796

2013

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Exploratory drug safety: A discovery strategy to reduce attrition in development

Journal of pharmacological and toxicological methods, 2009-07, Vol.60 (1), p.69-78

2009

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Safety pharmacology in 2010 and beyond: survey of significant events of the past 10 years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.7-15

2011

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Measuring the risk of torsades de pointes: Electrocardiographic evaluation of PNU-142093 in conscious cynomolgus non-human primates using restraint and non-restraint procedures

Journal of pharmacological and toxicological methods, 2009-07, Vol.60 (1), p.51-57

2009

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Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices

Journal of pharmacological and toxicological methods, 2005-07, Vol.52 (1), p.12-21

2005

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ILSI–HESI cardiovascular safety subcommittee dataset: An analysis of the statistical properties of QT interval and rate-corrected QT interval (QTc)

Journal of pharmacological and toxicological methods, 2007-09, Vol.56 (2), p.95-102

2007

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Challenges and lessons learned since implementation of the safety pharmacology guidance ICH S7A

Journal of pharmacological and toxicological methods, 2005-07, Vol.52 (1), p.22-29

2005

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Validation of a motor activity system by a robotically controlled vehicle and using standard reference compounds

Journal of pharmacological and toxicological methods, 2005-07, Vol.52 (1), p.159-167

2005

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New preclinical guidelines on drug effects on ventricular repolarization: Safety pharmacology comes of age

Journal of pharmacological and toxicological methods, 2004-05, Vol.49 (3), p.153-158

2004

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Introduction to Nonclinical Safety Pharmacology and the Safety Pharmacology Society

Journal of pharmacological and toxicological methods, 2004-05, Vol.49 (3), p.141-144

2004

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Dose-Related Antagonism of the Emetic Effect of Morphine by Methylnaltrexone in Dogs

Journal of clinical pharmacology, 1993-08, Vol.33 (8), p.747-751

1993

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Safety pharmacology in 2010 and beyond: Survey of significant events of the past 10years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.7-15

2011

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Evaluation of QTc prolongation in animal and human studies: A qualitative assessment of nonclinical and clinical concordance based on the literature

Journal of pharmacological and toxicological methods, 2012-09, Vol.66 (2), p.203-203

2012

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Memory, Myth, and Seduction: Unconscious Fantasy and the Interpretive Process

1, 2011

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Cardiac toxicity assessment and its relation to plasma level in various conscious animals

Journal of pharmacological and toxicological methods, 2010-09, Vol.62 (2), p.e24-e24

2010

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PII: S1056-8719(06)00019-0

Journal of pharmacological and toxicological methods, 2006, Vol.54 (2), p.91-93

2006

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Potentiation by Dopexamine of the Cardiac Responses to Circulating and Neuronally Released Norepinephrine: A Possible Mechanism for the Therapeutic Effects of the Drug

Journal of cardiovascular pharmacology, 1989-04, Vol.13 (4), p.667-671

1989

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WITHDRAWN: Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Journal of pharmacological and toxicological methods, 2008-05

2008

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Evaluation of drug‐induced QT interval prolongation in animal and human studies: a literature review of concordance

ILSI-HESI cardiovascular safety subcommittee initiative: Evaluation of three non-clinical models of QT prolongation

Response of safety pharmacologists to challenges arising from the rapidly evolving changes in the pharmaceutical industry

Is there a role for the no observed adverse effect level in safety pharmacology?

A Historical View and Vision into the Future of the Field of Safety Pharmacology

Benchmarking Safety Pharmacology regulatory packages and best practice

Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1)

Exploratory drug safety: A discovery strategy to reduce attrition in development

Safety pharmacology in 2010 and beyond: survey of significant events of the past 10 years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Measuring the risk of torsades de pointes: Electrocardiographic evaluation of PNU-142093 in conscious cynomolgus non-human primates using restraint and non-restraint procedures

Drugs effects on ventricular repolarization: A critical evaluation of the strengths and weaknesses of current methodologies and regulatory practices

ILSI–HESI cardiovascular safety subcommittee dataset: An analysis of the statistical properties of QT interval and rate-corrected QT interval (QTc)

Challenges and lessons learned since implementation of the safety pharmacology guidance ICH S7A

Validation of a motor activity system by a robotically controlled vehicle and using standard reference compounds

New preclinical guidelines on drug effects on ventricular repolarization: Safety pharmacology comes of age

Introduction to Nonclinical Safety Pharmacology and the Safety Pharmacology Society

Dose-Related Antagonism of the Emetic Effect of Morphine by Methylnaltrexone in Dogs

Safety pharmacology in 2010 and beyond: Survey of significant events of the past 10years and a roadmap to the immediate-, intermediate- and long-term future in recognition of the tenth anniversary of the Safety Pharmacology Society

Evaluation of QTc prolongation in animal and human studies: A qualitative assessment of nonclinical and clinical concordance based on the literature

Memory, Myth, and Seduction: Unconscious Fantasy and the Interpretive Process

Cardiac toxicity assessment and its relation to plasma level in various conscious animals

PII: S1056-8719(06)00019-0

Potentiation by Dopexamine of the Cardiac Responses to Circulating and Neuronally Released Norepinephrine: A Possible Mechanism for the Therapeutic Effects of the Drug

WITHDRAWN: Scientific review and recommendations on preclinical cardiovascular safety evaluation of biologics

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