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Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer

Frontiers in oncology, 2020-06, Vol.10, p.992-992

2020

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The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML

Blood, 2022-02, Vol.139 (6), p.894-906

2022

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Mesothelin: An Immunotherapeutic Target beyond Solid Tumors

Cancers, 2022-03, Vol.14 (6), p.1550

2022

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Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy

PloS one, 2015-10, Vol.10 (10), p.e0140564-e0140564

2015

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Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology

Molecular therapy. Methods & clinical development, 2020-12, Vol.19, p.201-209

2020

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Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21

Cells (Basel, Switzerland), 2022-02, Vol.11 (4), p.628

2022

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Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring

BMC medical genomics, 2020-03, Vol.13 (1), p.32-32, Article 32

2020

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Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies

Cells (Basel, Switzerland), 2021-10, Vol.10 (10), p.2698

2021

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The extracellular matrix: A key player in the pathogenesis of hematologic malignancies

Blood reviews, 2021-07, Vol.48, p.100787-100787, Article 100787

2021

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Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells

Molecular cancer therapeutics, 2013-11, Vol.12 (11), p.2296-2307

2013

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Regulation of Na,K-ATPase β1-subunit in TGF-β2-mediated epithelial-to-mesenchymal transition in human retinal pigmented epithelial cells

Experimental eye research, 2013-10, Vol.115, p.113-122

2013

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Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression

PloS one, 2015-04, Vol.10 (4), p.e0122442

2015

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Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity

Molecular cancer, 2015-08, Vol.14 (1), p.159-159, Article 159

2015

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Down syndrome and leukemia: An insight into the disease biology and current treatment options

Blood reviews, 2024-03, Vol.64, p.101154-101154, Article 101154

2024

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Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility

Molecular biology of the cell, 2005-03, Vol.16 (3), p.1082-1094

2005

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Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia

Seminars in oncology, 2017-04, Vol.44 (2), p.101-112

2017

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Tetraspanins set the stage for bone marrow microenvironment–induced chemoprotection in hematologic malignancies

Blood advances, 2023-08, Vol.7 (16), p.4403-4413

2023

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An Insight into the Role of Mesothelin in Pediatric Acute Myeloid Leukemia

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Strong concordance between RNA structural and single nucleotide variants identified via next generation sequencing techniques in primary pediatric leukemia and patient-derived xenograft samples

Genomics & informatics, 2020-03, Vol.18 (1), p.e6-e6

2020

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Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia

Leukemia research, 2017-05, Vol.56, p.36-43

2017

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Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells

American journal of physiology: Gastrointestinal and liver physiology, 2007-01, Vol.292 (1), p.G124-G133

2007

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Knockdown of sodium–calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells

The Journal of biological chemistry, 2017-07, Vol.292 (27), p.11388-11399

2017

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Bone Marrow Microenvironment-Induced Chemoprotection in KMT2A Rearranged Pediatric AML Is Overcome by Azacitidine-Panobinostat Combination

Cancers, 2023-06, Vol.15 (12), p.3112

2023

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Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts

Journal of clinical medicine, 2022-03, Vol.11 (7), p.1923

2022

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Sodium-Calcium Exchanger 1 Regulates Epithelial Cell Migration via Calcium-dependent Extracellular Signal-regulated Kinase Signaling

The Journal of biological chemistry, 2015-05, Vol.290 (20), p.12463-12473

2015

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Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer

The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML

Mesothelin: An Immunotherapeutic Target beyond Solid Tumors

Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy

Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology

Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21

Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring

Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies

The extracellular matrix: A key player in the pathogenesis of hematologic malignancies

Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells

Regulation of Na,K-ATPase β1-subunit in TGF-β2-mediated epithelial-to-mesenchymal transition in human retinal pigmented epithelial cells

Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression

Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity

Down syndrome and leukemia: An insight into the disease biology and current treatment options

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility

Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia

Tetraspanins set the stage for bone marrow microenvironment–induced chemoprotection in hematologic malignancies

An Insight into the Role of Mesothelin in Pediatric Acute Myeloid Leukemia

Strong concordance between RNA structural and single nucleotide variants identified via next generation sequencing techniques in primary pediatric leukemia and patient-derived xenograft samples

Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia

Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells

Knockdown of sodium–calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells

Bone Marrow Microenvironment-Induced Chemoprotection in KMT2A Rearranged Pediatric AML Is Overcome by Azacitidine-Panobinostat Combination

Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts

Sodium-Calcium Exchanger 1 Regulates Epithelial Cell Migration via Calcium-dependent Extracellular Signal-regulated Kinase Signaling

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