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A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity

Pflügers Archiv, 2021-07, Vol.473 (7), p.1009-1021

2021

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Physiology and pharmacology of the cardiac pacemaker ("funny") current

Pharmacology & therapeutics (Oxford), 2005-07, Vol.107 (1), p.59-79

2005

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Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (4), p.1705-1710

2011

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Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms

Frontiers in pharmacology, 2022-02, Vol.13, p.839004-839004

2022

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Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

eLife, 2022-03, Vol.11

2022

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Age-Related Changes in Cardiac Autonomic Modulation and Heart Rate Variability in Mice

Frontiers in neuroscience, 2021-05, Vol.15, p.617698-617698

2021

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Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations

International journal of molecular sciences, 2024-01, Vol.25 (2), p.980

2024

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A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability

Neurobiology of disease, 2018-10, Vol.118, p.55-63

2018

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Identification of the molecular site of ivabradine binding to HCN4 channels

PloS one, 2013-01, Vol.8 (1), p.e53132

2013

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Current-dependent Block of Rabbit Sino-Atrial Node If Channels by Ivabradine

The Journal of general physiology, 2002-07, Vol.120 (1), p.1-13

2002

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PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes

Frontiers in physiology, 2023-11, Vol.14, p.1250951-1250951

2023

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The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunction

Journal of interventional cardiac electrophysiology, 2015-08, Vol.43 (2), p.121-134

2015

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Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy

Advanced science, 2022-01, Vol.9 (2), p.e2101485-n/a

2022

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Identification of the natural chalcone glycoside hydroxysafflor yellow A as a suppressor of P53 overactivation‐associated hematopoietic defects

MedComm (2020), 2023-10, Vol.4 (5), p.e352-e352

2023

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Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models

Frontiers in physiology, 2012-01, Vol.3, p.240-240

2012

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Screening and Identification of Cardioprotective Compounds From Wenxin Keli by Activity Index Approach and in vivo Zebrafish Model

Frontiers in pharmacology, 2018-11, Vol.9, p.1288-1288

2018

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INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model

Scientific reports, 2016-04, Vol.6 (1), p.24515-24515, Article 24515

2016

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Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current

Journal of molecular and cellular cardiology, 2007-07, Vol.43 (1), p.39-48

2007

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A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability

Frontiers in molecular neuroscience, 2018-08, Vol.11, p.269-269

2018

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Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node

Journal of molecular and cellular cardiology, 2009-08, Vol.47 (2), p.221-227

2009

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Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells

Journal of molecular and cellular cardiology, 2009-03, Vol.46 (3), p.343-351

2009

Volltextzugriff (PDF)

Electrophysiology and pacemaker function of the developing sinoatrial node

American journal of physiology. Heart and circulatory physiology, 2007-11, Vol.293 (5), p.H2613-H2623

2007

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f/HCN channels: From a tiny current controlling cardiac pacemaking to a pleiotropic current all over the body

Progress in biophysics and molecular biology, 2021-11, Vol.166, p.1-2

2021

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The cardiac pacemaker current

Journal of molecular and cellular cardiology, 2010-01, Vol.48 (1), p.55-64

2010

Volltextzugriff (PDF)

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A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity

Physiology and pharmacology of the cardiac pacemaker ("funny") current

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms

Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

Age-Related Changes in Cardiac Autonomic Modulation and Heart Rate Variability in Mice

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations

A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability

Identification of the molecular site of ivabradine binding to HCN4 channels

Current-dependent Block of Rabbit Sino-Atrial Node If Channels by Ivabradine

PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes

The genetic basis for inherited forms of sinoatrial dysfunction and atrioventricular node dysfunction

Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy

Identification of the natural chalcone glycoside hydroxysafflor yellow A as a suppressor of P53 overactivation‐associated hematopoietic defects

Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models

Screening and Identification of Cardioprotective Compounds From Wenxin Keli by Activity Index Approach and in vivo Zebrafish Model

INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model

Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current

A Loss-of-Function HCN4 Mutation Associated With Familial Benign Myoclonic Epilepsy in Infancy Causes Increased Neuronal Excitability

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells

Electrophysiology and pacemaker function of the developing sinoatrial node

f/HCN channels: From a tiny current controlling cardiac pacemaking to a pleiotropic current all over the body

The cardiac pacemaker current

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