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Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Regulatory toxicology and pharmacology, 2015-08, Vol.72 (3), p.514-537

2015

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Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health

Frontiers in toxicology, 2022-09, Vol.4, p.964553-964553

2022

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Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data

Environmental and molecular mutagenesis, 2023-01, Vol.64 (1), p.4-15

2023

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Improving the chemical and sensory characteristics of red and white wines with pectinase‐producing non‐Saccharomyces yeasts

Journal of food science, 2022-12, Vol.87 (12), p.5402-5417

2022

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Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose

Environmental and molecular mutagenesis, 2023-02, Vol.64 (2), p.105-122

2023

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Development and application of consensus in silico models for advancing high-throughput toxicological predictions

Frontiers in pharmacology, 2024, Vol.15, p.1307905-1307905

2024

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From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow

Frontiers in toxicology, 2023-05, Vol.5, p.1194895-1194895

2023

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Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

Frontiers in toxicology, 2021-11, Vol.3, p.748406-748406

2021

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Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening

Frontiers in toxicology, 2022-09, Vol.4, p.981928-981928

2022

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Accelerating the Pace of Chemical Risk Assessment

Chemical research in toxicology, 2018-05, Vol.31 (5), p.287-290

2018

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DNA Damage Recognition in the Rat Zygote Following Chronic Paternal Cyclophosphamide Exposure

Toxicological sciences, 2007-12, Vol.100 (2), p.495-503

2007

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Epigenetic Programming in the Preimplantation Rat Embryo Is Disrupted by Chronic Paternal Cyclophosphamide Exposure

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (22), p.7865-7870

2005

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The Effects of Organophosphate Esters Used as Flame Retardants and Plasticizers on Granulosa, Leydig, and Spermatogonial Cells Analyzed Using High-Content Imaging

Toxicological sciences, 2022-03, Vol.186 (2), p.269-287

2022

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Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines

Biology of reproduction, 2022-03, Vol.106 (3), p.613-627

2022

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Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging

Toxicological sciences, 2021-04, Vol.180 (2), p.224-238

2021

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In Silico Models for Developmental Toxicity

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2425, p.217

2022

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Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties

Chemical research in toxicology, 2021-02, Vol.34 (2), p.616-633

2021

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Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

Archives of toxicology, 2017-05, Vol.91 (5), p.2045-2065

2017

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A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm

Toxicological sciences, 2022-11, Vol.190 (2), p.127-132

2022

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Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

Archives of toxicology, 2022-07, Vol.96 (7), p.2067-2085

2022

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Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment

Food and chemical toxicology, 2019-09, Vol.131, p.110581, Article 110581

2019

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Integrating in silico models to enhance predictivity for developmental toxicity

Toxicology (Amsterdam), 2016-08, Vol.370, p.127-137

2016

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New Quantitative Structure-Activity Relationship Models Improve Predictability of Ames Mutagenicity for Aromatic Azo Compounds

Toxicological sciences, 2016-10, Vol.153 (2), p.316-326

2016

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Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study

Regulatory toxicology and pharmacology, 2019-08, Vol.106 (C), p.278-291

2019

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Implementing in vitro bioactivity data to modernize priority setting of chemical inventories

ALTEX, 2022-01, Vol.39 (1), p.123-139

2022

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Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health

Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutagenicity and carcinogenicity dose–response data

Improving the chemical and sensory characteristics of red and white wines with pectinase‐producing non‐Saccharomyces yeasts

Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose

Development and application of consensus in silico models for advancing high-throughput toxicological predictions

From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow

Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening

Accelerating the Pace of Chemical Risk Assessment

DNA Damage Recognition in the Rat Zygote Following Chronic Paternal Cyclophosphamide Exposure

Epigenetic Programming in the Preimplantation Rat Embryo Is Disrupted by Chronic Paternal Cyclophosphamide Exposure

The Effects of Organophosphate Esters Used as Flame Retardants and Plasticizers on Granulosa, Leydig, and Spermatogonial Cells Analyzed Using High-Content Imaging

Phthalates and alternative plasticizers differentially affect phenotypic parameters in gonadal somatic and germ cell lines

Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging

In Silico Models for Developmental Toxicity

Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm

Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment

Integrating in silico models to enhance predictivity for developmental toxicity

New Quantitative Structure-Activity Relationship Models Improve Predictability of Ames Mutagenicity for Aromatic Azo Compounds

Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study

Implementing in vitro bioactivity data to modernize priority setting of chemical inventories

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