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Paracellular Diffusion in Caco-2 Cell Monolayers: Effect of Perturbation on the Transport of Hydrophilic Compounds That Vary in Charge and Size

Journal of pharmaceutical sciences, 1997-10, Vol.86 (10), p.1105-1110

1997

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Quantitative Approaches To Delineate Paracellular Diffusion in Cultured Epithelial Cell Monolayers

Journal of pharmaceutical sciences, 1994-11, Vol.83 (11), p.1529-1536

1994

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Passive Diffusion of Weak Organic Electrolytes across Caco‐2 Cell Monolayers: Uncoupling the Contributions of Hydrodynamic, Transcellular, and Paracellular Barriers

Journal of pharmaceutical sciences, 1995-10, Vol.84 (10), p.1197-1204

1995

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Increased lipophilicity and subsequent cell partitioning decrease passive transcellular diffusion of novel, highly lipophilic antioxidants

The Journal of pharmacology and experimental therapeutics, 1999-03, Vol.288 (3), p.1317

1999

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Interrelationships among physicochemical properties, absorption and anthelmintic activities of 2-desoxoparaherquamide and selected analogs

Journal of veterinary pharmacology and therapeutics, 2004-06, Vol.27 (3), p.169-181

2004

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Influence of organic acid excretion on cuticle pH and drug absorption by Haemonchus contortus

International journal for parasitology, 1996, Vol.26 (1), p.25-35

1996

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Biophysical transport properties of the cuticle of Ascaris suum

Molecular and biochemical parasitology, 1990, Vol.41 (2), p.153-165

1990

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A Biophysical Model of Passive and Polarized Active Transport Processes in Caco‐2 cells: Approaches to Uncoupling Apical and Basolateral Membrane Events in the Intact Cell

Journal of pharmaceutical sciences, 1995-01, Vol.84 (1), p.21-27

1995

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(D) Routes of delivery: Case studies: (3) Mechanistic insights to buccal delivery of proteinaceous substances

Advanced drug delivery reviews, 1992, Vol.8 (2), p.197-236

1992

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Theoretical Perspectives on Anthelmintic Drug Discovery: Interplay of Transport Kinetics, Physicochemical Properties, and in Vitro Activity of Anthelmintic Drugs

Journal of pharmaceutical sciences, 1994-07, Vol.83 (7), p.1052-1059

1994

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Properties of a selective kappa agonist, U-50,488H

Life sciences (1973), 1982-11, Vol.31 (20), p.2257-2260

1982

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Biophysical model approaches to mechanistic transepithelial studies of peptides

Journal of controlled release, 1990, Vol.11 (1), p.3-24

1990

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Transcellular permeability of chlorpromazine demonstrating the roles of protein binding and membrane partitioning

Pharmaceutical research, 1994-05, Vol.11 (5), p.665-673

1994

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Human buccal absorption of flurbiprofen

Clinical pharmacology and therapeutics, 1988-08, Vol.44 (2), p.225-231

1988

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Mechanisms of microenvironmental pH regulation in the cuticle of Ascaris suum

Molecular and biochemical parasitology, 1992-07, Vol.53 (1), p.135-148

1992

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Mechanistic studies in the transcuticular delivery of antiparasitic drugs II: ex vivo/in vitro correlation of solute transport by Ascaris suum

Molecular and biochemical parasitology, 1992-05, Vol.52 (1), p.1-13

1992

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Biophysical model for organic acid excretion in Ascaris suum

Molecular and biochemical parasitology, 1998-06, Vol.93 (2), p.179-190

1998

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Biophysical Model of the Transcuticular Excretion of Organic Acids, Cuticle pH and Buffer Capacity in Gastrointestinal Nematodes

Journal of drug targeting, 1994, Vol.2 (1), p.1-8

1994

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Local topical delivery of drugs: A model incorporating simultaneous diffusion and metabolic interconversion between drug and a single metabolite in the skin

Journal of theoretical biology, 1989-05, Vol.138 (1), p.1-15

1989

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U-50488H, a pure kappa receptor agonist with spinal analgesic loci in the mouse

Life Sciences [LIFE SCI.]. Vol. 31, no. 12-13. 1982, 1982-01, Vol.31 (12), p.1197-1200

1982

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Evidence for a central sympathoexcitatory action of alpha-2 adrenergic antagonists

The Journal of pharmacology and experimental therapeutics, 1983-03, Vol.224 (3), p.501

1983

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Pharmacological profile of the antidepressant adinazolam, a triazolobenzodiazepine

Neuropharmacology, 1983-11, Vol.22 (11), p.1277-1282

1983

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An analysis of binding at the opioid receptor based upon an agonist/antagonist two-state model

Molecular pharmacology, 1982-09, Vol.22 (2), p.349-359

1982

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The metabolism of 14C-tazadolene succinate in the dog

Xenobiotica, 1992, Vol.22 (8), p.963-971

1992

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Use of a Biophysical-Kinetic Model to Understand the Roles of Protein Binding and Membrane Partitioning on Passive Diffusion of Highly Lipophilic Molecules Across Cellular Barriers

Journal of drug targeting, 1993-01, Vol.1 (4), p.269-286

1993

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Paracellular Diffusion in Caco-2 Cell Monolayers: Effect of Perturbation on the Transport of Hydrophilic Compounds That Vary in Charge and Size

Quantitative Approaches To Delineate Paracellular Diffusion in Cultured Epithelial Cell Monolayers

Passive Diffusion of Weak Organic Electrolytes across Caco‐2 Cell Monolayers: Uncoupling the Contributions of Hydrodynamic, Transcellular, and Paracellular Barriers

Increased lipophilicity and subsequent cell partitioning decrease passive transcellular diffusion of novel, highly lipophilic antioxidants

Interrelationships among physicochemical properties, absorption and anthelmintic activities of 2-desoxoparaherquamide and selected analogs

Influence of organic acid excretion on cuticle pH and drug absorption by Haemonchus contortus

Biophysical transport properties of the cuticle of Ascaris suum

A Biophysical Model of Passive and Polarized Active Transport Processes in Caco‐2 cells: Approaches to Uncoupling Apical and Basolateral Membrane Events in the Intact Cell

(D) Routes of delivery: Case studies: (3) Mechanistic insights to buccal delivery of proteinaceous substances

Theoretical Perspectives on Anthelmintic Drug Discovery: Interplay of Transport Kinetics, Physicochemical Properties, and in Vitro Activity of Anthelmintic Drugs

Properties of a selective kappa agonist, U-50,488H

Biophysical model approaches to mechanistic transepithelial studies of peptides

Transcellular permeability of chlorpromazine demonstrating the roles of protein binding and membrane partitioning

Human buccal absorption of flurbiprofen

Mechanisms of microenvironmental pH regulation in the cuticle of Ascaris suum

Mechanistic studies in the transcuticular delivery of antiparasitic drugs II: ex vivo/in vitro correlation of solute transport by Ascaris suum

Biophysical model for organic acid excretion in Ascaris suum

Biophysical Model of the Transcuticular Excretion of Organic Acids, Cuticle pH and Buffer Capacity in Gastrointestinal Nematodes

Local topical delivery of drugs: A model incorporating simultaneous diffusion and metabolic interconversion between drug and a single metabolite in the skin

U-50488H, a pure kappa receptor agonist with spinal analgesic loci in the mouse

Evidence for a central sympathoexcitatory action of alpha-2 adrenergic antagonists

Pharmacological profile of the antidepressant adinazolam, a triazolobenzodiazepine

An analysis of binding at the opioid receptor based upon an agonist/antagonist two-state model

The metabolism of 14C-tazadolene succinate in the dog

Use of a Biophysical-Kinetic Model to Understand the Roles of Protein Binding and Membrane Partitioning on Passive Diffusion of Highly Lipophilic Molecules Across Cellular Barriers

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