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A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment

Leukemia research, 2010-10, Vol.34 (10), p.1383-1389

2010

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Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome

Biochemical pharmacology, 2007-06, Vol.73 (12), p.1863-1872

2007

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Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid

Biochemical pharmacology, 1998-03, Vol.55 (5), p.635-648

1998

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F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action

Biochemical pharmacology, 2000-04, Vol.59 (7), p.807-819

2000

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Characterization of DNA-strand breakage induced in V79 cells by F 11782, a catalytic inhibitor of topoisomerases

British journal of cancer, 2000-12, Vol.83 (12), p.1740-1746

2000

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Deficient nucleotide excision repair activity in protein extracts from normal human lymphocytes

Carcinogenesis (New York), 1995-07, Vol.16 (7), p.1611-1616

1995

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In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs

Cancer chemotherapy and pharmacology, 2000, Vol.45 (6), p.471-476

2000

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Markedly diminished drug resistance-inducing properties of vinflunine (20', 20'-difluoro-3', 4'-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro

Cancer chemotherapy and pharmacology, 2001-07, Vol.48 (1), p.62-70

2001

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Vinflunine (20', 20'-difluoro-3', 4'-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro

Investigational new drugs, 1998-01, Vol.16 (1), p.3-17

1998

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Evaluation of DNA repair inhibition by antitumor or antibiotic drugs using a chemiluminescence microplate assay

Carcinogenesis (New York), 1997-12, Vol.18 (12), p.2441-2445

1997

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Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells

Anti-cancer drugs, 1999-07, Vol.10 (6), p.537-544

1999

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DNA repair mechanisms associated with cellular resistance to antitumor drugs: potential novel targets

Anti-cancer drugs, 1998-02, Vol.9 (2), p.105-123

1998

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Novel artificial endonucleases inhibit base excision repair and potentiate the cytotoxicity of DNA-damaging agents on L1210 cells

Anti-cancer drugs, 1999-01, Vol.10 (1), p.55-66

1999

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F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103

Cancer chemotherapy and pharmacology, 2000, Vol.46 (2), p.101-113

2000

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DNA repair activity in protein extracts of fresh human malignant lymphoid cells

Molecular pharmacology, 1996-05, Vol.49 (5), p.766-771

1996

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Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action

Anti-cancer drugs, 2000-11, Vol.11 (10), p.829-841

2000

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Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II

Anticancer research, 2000-11, Vol.20 (6B), p.4557

2000

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Activated ras oncogene and specifically acquired resistance to cisplatin in human mammary epithelial cells: induction of DNA cross-links and their repair

Carcinogenesis (New York), 1994-05, Vol.15 (5), p.845-850

1994

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Integrated system for the screening of the specificity of protein kinase inhibitors

Biochemical pharmacology, 1993-08, Vol.46 (3), p.439-448

1993

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A cisplatin-resistant murine leukemia cell line exhibits increased topoisomerase II activity

Molecular pharmacology, 1994-09, Vol.46 (3), p.431

1994

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In vivo synergism between chemotherapy and the 3C23K monoclonal antibody targeting the AMH-type II receptor in ovarian cancer PDX models

Annals of oncology, 2015-03, Vol.26, p.ii23

2015

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Requirements for P-glycoprotein recognition based on structure-activity relationships in the podophyllotoxin series

Anti-cancer drug design, 1998-06, Vol.13 (4), p.317

1998

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Studies of the potency of protein kinase inhibitors on ATPase activities

Chemico-biological interactions, 1993, Vol.86 (1), p.17-27

1993

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DNA excision‐repair synthesis is enhanced in a murine leukemia L1210 cell line resistant to cisplatin

European journal of biochemistry, 1993-02, Vol.211 (3), p.403-409

1993

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Substrate phosphorylation capacities of the major tyrosine protein kinase from the human promyelocytic cell line, HL-60

International Journal of Peptide and Protein Research, 1994-05, Vol.43 (5), p.496-504

1994

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A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment

Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome

Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid

F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action

Characterization of DNA-strand breakage induced in V79 cells by F 11782, a catalytic inhibitor of topoisomerases

Deficient nucleotide excision repair activity in protein extracts from normal human lymphocytes

In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs

Markedly diminished drug resistance-inducing properties of vinflunine (20', 20'-difluoro-3', 4'-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro

Vinflunine (20', 20'-difluoro-3', 4'-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro

Evaluation of DNA repair inhibition by antitumor or antibiotic drugs using a chemiluminescence microplate assay

Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells

DNA repair mechanisms associated with cellular resistance to antitumor drugs: potential novel targets

Novel artificial endonucleases inhibit base excision repair and potentiate the cytotoxicity of DNA-damaging agents on L1210 cells

F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103

DNA repair activity in protein extracts of fresh human malignant lymphoid cells

Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action

Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II

Activated ras oncogene and specifically acquired resistance to cisplatin in human mammary epithelial cells: induction of DNA cross-links and their repair

Integrated system for the screening of the specificity of protein kinase inhibitors

A cisplatin-resistant murine leukemia cell line exhibits increased topoisomerase II activity

In vivo synergism between chemotherapy and the 3C23K monoclonal antibody targeting the AMH-type II receptor in ovarian cancer PDX models

Requirements for P-glycoprotein recognition based on structure-activity relationships in the podophyllotoxin series

Studies of the potency of protein kinase inhibitors on ATPase activities

DNA excision‐repair synthesis is enhanced in a murine leukemia L1210 cell line resistant to cisplatin

Substrate phosphorylation capacities of the major tyrosine protein kinase from the human promyelocytic cell line, HL-60

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