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In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N -Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis

Frontiers in pharmacology, 2020-12, Vol.11, p.590544

2020

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Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet

Journal of Pharmacological Sciences, 2013/09/20, Vol.123(1), pp.47-57

2013

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Vasodilatory activity and antihypertensive profile mediated by inhibition of phosphodiesterase type 1 induced by a novel sulfonamide compound

Fundamental & clinical pharmacology, 2012-12, Vol.26 (6), p.690-700

2012

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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

PloS one, 2022-06, Vol.17 (6), p.e0269447-e0269447

2022

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Efeito Anti-Hipertensivo de Novos Agonistas do Receptor de Adenosina em Ratos Espontaneamente Hipertensos

Arquivos brasileiros de cardiologia, 2024, Vol.121 (2)

2024

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Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

Pharmaceuticals (Basel, Switzerland), 2023-01, Vol.16 (2), p.209

2023

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LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice

PloS one, 2018-07, Vol.13 (7), p.e0199009-e0199009

2018

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Cytotoxic Guanidine Alkaloids from Pterogyne nitens

Journal of natural products (Washington, D.C.), 2009-03, Vol.72 (3), p.473-476

2009

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Vasodilator and antihypertensive effects of a novel N-acylhydrazone derivative mediated by the inhibition of L-type Ca2+ channels

Fundamental & clinical pharmacology, 2014-02, Vol.28 (1), p.29-41

2014

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How to get to the green-yellow (Brazilian) pharmaceuticals?

Journal of the Brazilian Chemical Society, 2010-12, Vol.21 (12), p.2173-2174

2010

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Oral Antithrombotic Effects of Acylhydrazone Derivatives

Journal of Atherosclerosis and Thrombosis, 2013, Vol.20(3), pp.287-295

2013

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Simple HPLC-UV for the quantification of a new leishmanicidal candidate (E)-1-4(trifluoromethyl) benzylidene)-5-(2-4-dichlorozoyl) carbonylhydrazine (LASSBio-1736) in rat plasma for pharmacokinetics assessment

Biomedical chromatography, 2016-07, Vol.30 (7), p.1029-1035

2016

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Antinociceptive Profile of 2,3,6-Trisubstituted Piperidine Alkaloids: 3-O-Acetyl-spectaline and Semi-synthetic Derivatives of (−)-Spectaline

Chemical and Pharmaceutical Bulletin, 2008/04/01, Vol.56(4), pp.407-412

2008

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Antimicrobial activity of Pterogyne nitens Tul., Fabaceae, against opportunistic fungi

Revista brasileira de farmacognosia, 2010-11, Vol.20 (5), p.706-711

2010

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Efeito Anti-Hipertensivo de Novos Agonistas do Receptor de Adenosina em Ratos Espontaneamente Hipertensos

Arquivos brasileiros de cardiologia, 2024-03, Vol.121 (2)

2024

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Semicarbazone derivatives as promising therapeutic alternatives in leishmaniasis

Experimental parasitology, 2019-06, Vol.201, p.57-66

2019

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Antihypertensive Effect of New Agonist of Adenosine Receptor in Spontaneously Hypertensive Rats

Arquivos brasileiros de cardiologia, 2024, Vol.121 (2), p.e20230405-e20230405

2024

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A NOVEL ROLE OF LASSBio‐788 IN INHIBITING NF‐&[Kappa]B MEDIATED SIGNALING IN PLATELET OF HYPERCHOLESTEROLEMIC RATS

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Lung and liver responses to 1- and 7-day treatments with LASSBio-596 in mice subchronically intoxicated by microcystin-LR

Toxicon (Oxford), 2018-01, Vol.141, p.1-8

2018

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LASSBio-596: a New Pre-clinical Candidate for Rheumatoid Arthritis?

Inflammation, 2022-04, Vol.45 (2), p.528-543

2022

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LASSBio-1425, an analog of thalidomide, decreases triglyceride and increases HDL cholesterol levels by inhibition of TNF-α production

International journal of cardiology, 2016-01, Vol.202, p.497-499

2016

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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

PloS one, 2022-01, Vol.17 (6)

2022

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N-acylhydrazone improves exercise intolerance in rats submitted to myocardial infarction by the recovery of calcium homeostasis in skeletal muscle

Life sciences (1973), 2014-01, Vol.94 (1), p.30-36

2014

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Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

Frontiers in physiology, 2015-09, Vol.6, p.267-267

2015

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In Vitro, In Vivo and In Silico Effectiveness of LASSBio-1386, an N -Acyl Hydrazone Derivative Phosphodiesterase-4 Inhibitor, Against Leishmania amazonensis

Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet

Vasodilatory activity and antihypertensive profile mediated by inhibition of phosphodiesterase type 1 induced by a novel sulfonamide compound

Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

Efeito Anti-Hipertensivo de Novos Agonistas do Receptor de Adenosina em Ratos Espontaneamente Hipertensos

Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice

Respiratory and Systemic Effects of LASSBio596 Plus Surfactant in Experimental Acute Respiratory Distress Syndrome

Cytotoxic Guanidine Alkaloids from Pterogyne nitens

Vasodilator and antihypertensive effects of a novel N-acylhydrazone derivative mediated by the inhibition of L-type Ca2+ channels

How to get to the green-yellow (Brazilian) pharmaceuticals?

Oral Antithrombotic Effects of Acylhydrazone Derivatives

Simple HPLC-UV for the quantification of a new leishmanicidal candidate (E)-1-4(trifluoromethyl) benzylidene)-5-(2-4-dichlorozoyl) carbonylhydrazine (LASSBio-1736) in rat plasma for pharmacokinetics assessment

Antinociceptive Profile of 2,3,6-Trisubstituted Piperidine Alkaloids: 3-O-Acetyl-spectaline and Semi-synthetic Derivatives of (−)-Spectaline

Antimicrobial activity of Pterogyne nitens Tul., Fabaceae, against opportunistic fungi

Efeito Anti-Hipertensivo de Novos Agonistas do Receptor de Adenosina em Ratos Espontaneamente Hipertensos

Semicarbazone derivatives as promising therapeutic alternatives in leishmaniasis

Antihypertensive Effect of New Agonist of Adenosine Receptor in Spontaneously Hypertensive Rats

A NOVEL ROLE OF LASSBio‐788 IN INHIBITING NF‐&[Kappa]B MEDIATED SIGNALING IN PLATELET OF HYPERCHOLESTEROLEMIC RATS

Lung and liver responses to 1- and 7-day treatments with LASSBio-596 in mice subchronically intoxicated by microcystin-LR

LASSBio-596: a New Pre-clinical Candidate for Rheumatoid Arthritis?

LASSBio-1425, an analog of thalidomide, decreases triglyceride and increases HDL cholesterol levels by inhibition of TNF-α production

Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

N-acylhydrazone improves exercise intolerance in rats submitted to myocardial infarction by the recovery of calcium homeostasis in skeletal muscle

Therapeutic effects of LASSBio-596 in an elastase-induced mouse model of emphysema

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