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The confluence of big data and evolutionary genome mining for the discovery of natural products

Natural product reports, 2021-11, Vol.38 (11), p.224-24

2021

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Evolutionary dynamics of natural product biosynthesis in bacteria

Natural product reports, 2020-04, Vol.37 (4), p.566-599

2020

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Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB

Protein science, 2021-09, Vol.30 (9), p.1904-1918

2021

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Unlocking a high bacterial diversity in the coralloid root microbiome from the cycad genus Dioon

PloS one, 2019-02, Vol.14 (2), p.e0211271-e0211271

2019

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Desert Environments Facilitate Unique Evolution of Biosynthetic Potential in Streptomyces

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.588

2021

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Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

Frontiers in microbiology, 2019-11, Vol.10, p.2550-2550

2019

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Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer

Molecular biology and evolution, 2013-09, Vol.30 (9), p.2024-2034

2013

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Diverse Cone-Snail Species Harbor Closely Related Streptomyces Species with Conserved Chemical and Genetic Profiles, Including Polycyclic Tetramic Acid Macrolactams

Frontiers in microbiology, 2017-11, Vol.8, p.2305

2017

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Genomic surveillance links livestock production with the emergence and spread of multi-drug resistant non-typhoidal Salmonella in Mexico

The Journal of Microbiology, 2019, 57(4), , pp.271-280

2019

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Evolution of substrate specificity in a retained enzyme driven by gene loss

eLife, 2017-03, Vol.6

2017

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Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems

Microbial biotechnology, 2011-03, Vol.4 (2), p.275-285

2011

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First Draft Genome Sequence of a Strain from the Genus Citricoccus

Journal of Bacteriology, 2011-11, Vol.193 (21), p.6092-6093

2011

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Phylogenomics of 2,4-Diacetylphloroglucinol-Producing Pseudomonas and Novel Antiglycation Endophytes from Piper auritum

Journal of natural products (Washington, D.C.), 2017-07, Vol.80 (7), p.1955-1963

2017

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Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis

EMBO reports, 2003-03, Vol.4 (3), p.296-300

2003

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Synthetic biology of avermectin for production improvement and structure diversification

Biotechnology journal, 2014-03, Vol.9 (3), p.316-325

2014

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Re‐annotation of the sequence > annotation: opportunities for the functional microbiologist

Microbial biotechnology, 2015-01, Vol.8 (1), p.2-4

Barona‐Gómez, Francisco

2015

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A computational framework to explore large-scale biosynthetic diversity

Nature chemical biology, 2020-01, Vol.16 (1), p.60-68

2020

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Phenotypic heterogeneity in Streptomyces colonies

Current opinion in microbiology, 2024-04, Vol.78, p.102448-102448, Article 102448

2024

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Identification and analysis of residues contained on β → α loops of the dual‐substrate (βα)8 phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity

Protein science, 2010-03, Vol.19 (3), p.535-543

2010

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Streptomyces lividans 66 produces a protease inhibitor via a tRNA-utilizing enzyme interacting with a C-minus NRPS

Journal of industrial microbiology & biotechnology, 2023-09, Vol.50 (1)

2023

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Genomic insights into Mycobacterium simiae human colonization

Standards in genomic sciences, 2018-01, Vol.13 (1), Article 1

2018

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Microbial Diversity in Cultivated and Feral Vanilla Vanilla planifolia Orchids Affected by Stem and Rot Disease

Microbial ecology, 2022-10, Vol.84 (3), p.821-833

2022

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Expression in CHO cells of a bacterial biosynthetic pathway producing a small non-ribosomal peptide aldehyde prevents proteolysis of recombinant proteins

Metabolic engineering, 2024-03, Vol.82, p.79-88

2024

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Molecular annotation of ketol‐acid reductoisomerases from Streptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity

Microbial biotechnology, 2015-03, Vol.8 (2), p.239-252

2015

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The confluence of big data and evolutionary genome mining for the discovery of natural products

Evolutionary dynamics of natural product biosynthesis in bacteria

Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB

Unlocking a high bacterial diversity in the coralloid root microbiome from the cycad genus Dioon

Desert Environments Facilitate Unique Evolution of Biosynthetic Potential in Streptomyces

Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer

Diverse Cone-Snail Species Harbor Closely Related Streptomyces Species with Conserved Chemical and Genetic Profiles, Including Polycyclic Tetramic Acid Macrolactams

Genomic surveillance links livestock production with the emergence and spread of multi-drug resistant non-typhoidal Salmonella in Mexico

Evolution of substrate specificity in a retained enzyme driven by gene loss

Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems

First Draft Genome Sequence of a Strain from the Genus Citricoccus

Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms

Phylogenomics of 2,4-Diacetylphloroglucinol-Producing Pseudomonas and Novel Antiglycation Endophytes from Piper auritum

Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis

Synthetic biology of avermectin for production improvement and structure diversification

Re‐annotation of the sequence > annotation: opportunities for the functional microbiologist

A computational framework to explore large-scale biosynthetic diversity

Phenotypic heterogeneity in Streptomyces colonies

Identification and analysis of residues contained on β → α loops of the dual‐substrate (βα)8 phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity

Streptomyces lividans 66 produces a protease inhibitor via a tRNA-utilizing enzyme interacting with a C-minus NRPS

Genomic insights into Mycobacterium simiae human colonization

Microbial Diversity in Cultivated and Feral Vanilla Vanilla planifolia Orchids Affected by Stem and Rot Disease

Expression in CHO cells of a bacterial biosynthetic pathway producing a small non-ribosomal peptide aldehyde prevents proteolysis of recombinant proteins

Molecular annotation of ketol‐acid reductoisomerases from Streptomyces reveals a novel amino acid biosynthesis interlock mediated by enzyme promiscuity

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