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Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers

Journal of Nuclear Medicine, 2017-09, Vol.58 (Suppl 2), p.17S-26S

2017

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Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments

Nature communications, 2020-06, Vol.11 (1), p.3123-3123, Article 3123

2020

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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

Scientific reports, 2019-04, Vol.9 (1), p.6136-6136, Article 6136

2019

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SART3 associates with a post-splicing complex

Journal of cell science, 2023-01, Vol.136 (2)

2023

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Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor

International journal of molecular sciences, 2024-01, Vol.25 (2), p.1358

2024

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Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors

Scientific reports, 2024-08, Vol.14 (1), p.20160-13, Article 20160

2024

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Characterization of the class IIa histone deacetylases substrate specificity

The FASEB journal, 2022-05, Vol.36 (5), p.e22287-n/a

2022

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BRAT1 links Integrator and defective RNA processing with neurodegeneration

Nature communications, 2022-08, Vol.13 (1), p.5026-5026, Article 5026

2022

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Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7416

2023

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Heterologous expression and purification of recombinant human protoporphyrinogen oxidase IX: A comparative study

PloS one, 2021-11, Vol.16 (11), p.e0259837-e0259837

2021

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The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries

The FASEB journal, 2019-03, Vol.33 (3), p.4035-4045

2019

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Tunable Multivalent Platform for Immune Recruitment to Lower Antigen Expressing Cancers

Angewandte Chemie International Edition, 2023-02, Vol.62 (9), p.e202214659-n/a

International ed. in English, 2023

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Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells

International journal of molecular sciences, 2023-03, Vol.24 (5), p.4720

2023

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Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene

Scientific reports, 2022-10, Vol.12 (1), p.17081-17081, Article 17081

2022

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Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

International journal of molecular sciences, 2021-12, Vol.23 (1), p.369

2021

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Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

The EMBO journal, 2006-03, Vol.25 (6), p.1375-1384

2006

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Characterization of glutamate carboxypeptidase 2 orthologs in trematodes

Parasites & vectors, 2022-12, Vol.15 (1), p.480-480, Article 480

2022

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Engineered Fragments of the PSMA-Specific 5D3 Antibody and Their Functional Characterization

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6672

2020

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Evaluation of 111In-DOTA-5D3, a Surrogate SPECT Imaging Agent for Radioimmunotherapy of Prostate-Specific Membrane Antigen

The Journal of nuclear medicine (1978), 2019-03, Vol.60 (3), p.400-406

2019

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Structural and biochemical characterization of the folyl‐poly‐γ‐l‐glutamate hydrolyzing activity of human glutamate carboxypeptidase II

The FEBS journal, 2014-07, Vol.281 (14), p.3228-3242

2014

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A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging

Nature communications, 2021-09, Vol.12 (1), p.5460-11, Article 5460

2021

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Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

Journal of medicinal chemistry, 2019-09, Vol.62 (18), p.8557-8577

2019

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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Journal of molecular biology, 2008-03, Vol.376 (5), p.1438-1450

2008

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Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.706-712

2020

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Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models

Journal of medicinal chemistry, 2020-09, Vol.63 (18), p.10246-10262

2020

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Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers

Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

SART3 associates with a post-splicing complex

Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor

Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors

Characterization of the class IIa histone deacetylases substrate specificity

BRAT1 links Integrator and defective RNA processing with neurodegeneration

Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines

Heterologous expression and purification of recombinant human protoporphyrinogen oxidase IX: A comparative study

The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries

Tunable Multivalent Platform for Immune Recruitment to Lower Antigen Expressing Cancers

Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity

Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

Characterization of glutamate carboxypeptidase 2 orthologs in trematodes

Engineered Fragments of the PSMA-Specific 5D3 Antibody and Their Functional Characterization

Evaluation of 111In-DOTA-5D3, a Surrogate SPECT Imaging Agent for Radioimmunotherapy of Prostate-Specific Membrane Antigen

Structural and biochemical characterization of the folyl‐poly‐γ‐l‐glutamate hydrolyzing activity of human glutamate carboxypeptidase II

A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging

Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models

Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models

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