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Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats

Pharmacology research & perspectives, 2020-04, Vol.8 (2), p.e00579-n/a

2020

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Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator

Bioorganic & medicinal chemistry letters, 2021-05, Vol.40, p.127886, Article 127886

2021

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Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans

ACS medicinal chemistry letters, 2016-05, Vol.7 (5), p.465-469

2016

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Nucleophilic addition reactions of 2-nitro-1-(phenylsulfonyl)indole. A new synthesis of 3-substituted-2-nitroindoles

Tetrahedron letters, 1999-10, Vol.40 (43), p.7615-7619

1999

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Syntheses and Diels-Alder cycloaddition reactions of 4H-furo[3,4-b]indoles. A regiospecific Diels-Alder synthesis of ellipticine

Journal of organic chemistry, 1992-10, Vol.57 (22), p.5878-5891

1992

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Discrimination between exo- and endo-3,2-methyl shifts in substituted 2-norbornyl cations on the (+)-camphenilone route to (-)-albene

Journal of the American Chemical Society, 1983-10, Vol.105 (22), p.6656-6662

1983

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"Glycylcyclines". 3. 9-Aminodoxycyclinecarboxamides

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3205-3211

1994

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Thermal stereomutations of (2R,3R)-phenylcyclopropane-1,2,3-2H3 and (1R,2S,3R)-phenylcyclopropane-2-13C-1,2,3-2H3: quantification of all four stereochemical modes for interconversions among the 1-phenyl-1,2,3-trideuteriocyclopropanes

Journal of the American Chemical Society, 1984-09, Vol.106 (18), p.5312-5319

1984

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Restricted Nitrogen Inversion in 9,10- Diazatetracyclo[6.3.0.0.4,110.5,9]undecanes. Dynamic NMR Studies

Journal of organic chemistry, 1998-05, Vol.63 (11), p.3775-3777

1998

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Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects

BMC pharmacology & toxicology, 2015-09, Vol.16 (S1), p.A59-A59, Article A59

2015

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Stereocontrolled total syntheses of (-)-hobartine and (+)-aristoteline via an intramolecular nitrone-olefin cycloaddition

Journal of organic chemistry, 1985-12, Vol.50 (26), p.5900-5902

1985

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Partial loss of deuterium label in Wilkinson's catalyst promoted decarbonylations of deuterioaldehydes

Journal of organic chemistry, 1987-07, Vol.52 (15), p.3303-3307

1987

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Absolute configurations, maximum rotations, and kinetics of thermal racemization of the 1-phenyl-2-deuteriocyclopropanes

Journal of the American Chemical Society, 1984-10, Vol.106 (21), p.6364-6367

1984

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ChemInform Abstract: Indoles: Industrial, Agricultural and Over-the-counter Uses

ChemInform, 2011-10, Vol.42 (43), p.no-no

Barden, Timothy C.

2011

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A directed metalation route to the zwitterionic indole alkaloids

Tetrahedron, 1988-01, Vol.44 (11), p.3195-3202

1988

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Stereochemical kinetics of the thermal stereomutations interconverting achiral isomers of 1-phenyl-1,2,3-trideuteriocyclopropane

Journal of the American Chemical Society, 1984-03, Vol.106 (5), p.1421-1426

1984

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Reinterpretation of two degradations of (-)-albene

Journal of organic chemistry, 1986-04, Vol.51 (7), p.1133-1135

1986

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Absolute stereochemistry of (-)-albene

Journal of organic chemistry, 1983-02, Vol.48 (4), p.625-626

1983

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Total synthesis of (.+-.)-albene

Journal of organic chemistry, 1981-06, Vol.46 (12), p.2442-2445

1981

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Indoles: Industrial, Agricultural and Over-the-Counter Uses

Heterocyclic Scaffolds II, 2010, Vol.26, p.31-46

2010

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A directed metalation route to the zwitterionic indole alkaloids. : Synthesis of sempervirine

Tetrahedron, 1988, Vol.44 (11), p.3195-3202

1988

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ChemInform Abstract: Nucleophilic Addition Reactions of 2-Nitro-1-(phenylsulfonyl)indole. A New Synthesis of 3-Substituted-2-nitroindoles

ChemInform, 2000-01, Vol.31 (3), p.no-no

2000

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Comparative mitochondrial genomics of sponge-dwelling snapping shrimps in the genus Synalpheus: Exploring differences between eusocial and non-eusocial species and insights into phylogenetic relationships in caridean shrimps

Gene, 2021-06, Vol.786, p.145624-145624, Article 145624

2021

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CANDELS: THE COSMIC ASSEMBLY NEAR-INFRARED DEEP EXTRAGALACTIC LEGACY SURVEY

The Astrophysical journal. Supplement series, 2011-12, Vol.197 (2), p.35

2011

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IOPscience - CANDELS: The Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey—The Hubble Space Telescope Observations, Imaging Data Products, and Mosaics

The Astrophysical journal. Supplement series, 2011-12, Vol.197, p.36

2011

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Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats

Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator

Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans

Nucleophilic addition reactions of 2-nitro-1-(phenylsulfonyl)indole. A new synthesis of 3-substituted-2-nitroindoles

Syntheses and Diels-Alder cycloaddition reactions of 4H-furo[3,4-b]indoles. A regiospecific Diels-Alder synthesis of ellipticine

Discrimination between exo- and endo-3,2-methyl shifts in substituted 2-norbornyl cations on the (+)-camphenilone route to (-)-albene

"Glycylcyclines". 3. 9-Aminodoxycyclinecarboxamides

Thermal stereomutations of (2R,3R)-phenylcyclopropane-1,2,3-2H3 and (1R,2S,3R)-phenylcyclopropane-2-13C-1,2,3-2H3: quantification of all four stereochemical modes for interconversions among the 1-phenyl-1,2,3-trideuteriocyclopropanes

Restricted Nitrogen Inversion in 9,10- Diazatetracyclo[6.3.0.0.4,110.5,9]undecanes. Dynamic NMR Studies

Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects

Stereocontrolled total syntheses of (-)-hobartine and (+)-aristoteline via an intramolecular nitrone-olefin cycloaddition

Partial loss of deuterium label in Wilkinson's catalyst promoted decarbonylations of deuterioaldehydes

Absolute configurations, maximum rotations, and kinetics of thermal racemization of the 1-phenyl-2-deuteriocyclopropanes

ChemInform Abstract: Indoles: Industrial, Agricultural and Over-the-counter Uses

A directed metalation route to the zwitterionic indole alkaloids

Stereochemical kinetics of the thermal stereomutations interconverting achiral isomers of 1-phenyl-1,2,3-trideuteriocyclopropane

Reinterpretation of two degradations of (-)-albene

Absolute stereochemistry of (-)-albene

Total synthesis of (.+-.)-albene

Indoles: Industrial, Agricultural and Over-the-Counter Uses

A directed metalation route to the zwitterionic indole alkaloids. : Synthesis of sempervirine

ChemInform Abstract: Nucleophilic Addition Reactions of 2-Nitro-1-(phenylsulfonyl)indole. A New Synthesis of 3-Substituted-2-nitroindoles

Comparative mitochondrial genomics of sponge-dwelling snapping shrimps in the genus Synalpheus: Exploring differences between eusocial and non-eusocial species and insights into phylogenetic relationships in caridean shrimps

CANDELS: THE COSMIC ASSEMBLY NEAR-INFRARED DEEP EXTRAGALACTIC LEGACY SURVEY

IOPscience - CANDELS: The Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey—The Hubble Space Telescope Observations, Imaging Data Products, and Mosaics

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