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Identification of Surrogate Agonists and Antagonists for Orphan G-Protein-Coupled Receptor GPR139

Journal of biomolecular screening, 2009-08, Vol.14 (7), p.789-797

2009

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Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.1101-1106

2005

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Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Asymmetric Synthesis of the C(9−25) Spiroketal Dipropionate Subunit

Journal of the American Chemical Society, 1999-11, Vol.121 (45), p.10468-10477

1999

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Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1382-1391

1998

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Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Cyanotetraene Construction, Asymmetric Synthesis of the C(26−37) Oxazole, Fragment Assembly, and Final Elaboration

Journal of the American Chemical Society, 1999-11, Vol.121 (45), p.10478-10486

1999

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Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2

ACS medicinal chemistry letters, 2022-07, Vol.13 (7), p.1159-1164

2022

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Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (6), p.1525-1528

2016

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4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase

Bioorganic & medicinal chemistry letters, 2016-02, Vol.26 (4), p.1184-1187

2016

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Total Synthesis of (+)-Calyculin A and (−)-Calyculin B

Journal of organic chemistry, 1998-10, Vol.63 (22), p.7596-7597

1998

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Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3836-3839

2015

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Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Journal of medicinal chemistry, 2009-07, Vol.52 (13), p.3941-3953

2009

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Novel inhibitors of the high-affinity l-proline transporter as potential therapeutic agents for the treatment of cognitive disorders

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (16), p.3886-3890

2014

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(+)-Trienomycins A, B, C, and F and (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry

Journal of the American Chemical Society, 1996-09, Vol.118 (35), p.8308-8315

1996

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Identification of potent pyrimidine inhibitors of phosphodiesterase 7 (PDE7) and their ability to inhibit T cell proliferation

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (7), p.1935-1938

2009

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Understanding Wheel Spinning in the Context of Affective Factors

International journal of people-oriented programming, 2014-07, Vol.3 (2), p.75-90

2014

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Fused pyrimidine based inhibitors of phosphodiesterase 7 (PDE7): synthesis and initial structure–activity relationships

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (7), p.1829-1833

2005

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Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors

Journal of medicinal chemistry, 2003-05, Vol.46 (10), p.1831-1844

2003

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Identification of purine inhibitors of phosphodiesterase 7 (PDE7)

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (11), p.2955-2958

2004

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Complestatin synthetic studies

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1697-1702

2004

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Complestatin synthetic studies: the effect of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1697-1702

2004

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Total Syntheses of (+)-Trienomycins A and F via a Unified Strategy

Journal of the American Chemical Society, 1996-09, Vol.118 (35), p.8316-8328

1996

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Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1

Journal of the American Chemical Society, 1999-10, Vol.121 (40), p.9286-9298

1999

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Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase

Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (22), p.3133-3136

1998

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Synthesis and Biological Activity of Cyclic Peptide Inhibitors of Ribonucleotide Reductase

Organic letters, 1999-10, Vol.1 (8), p.1201-1204

1999

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Total Synthesis of (+)-Trienomycins A and F

Journal of the American Chemical Society, 1995-11, Vol.117 (43), p.10777-10778

1995

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Identification of Surrogate Agonists and Antagonists for Orphan G-Protein-Coupled Receptor GPR139

Structure-based design of potent and selective inhibitors of collagenase-3 (MMP-13)

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Asymmetric Synthesis of the C(9−25) Spiroketal Dipropionate Subunit

Modulation of Receptor and Receptor Subtype Affinities Using Diastereomeric and Enantiomeric Monosaccharide Scaffolds as a Means to Structural and Biological Diversity. A New Route to Ether Synthesis

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B: Cyanotetraene Construction, Asymmetric Synthesis of the C(26−37) Oxazole, Fragment Assembly, and Final Elaboration

Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2

Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase

4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase

Total Synthesis of (+)-Calyculin A and (−)-Calyculin B

Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome

Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Novel inhibitors of the high-affinity l-proline transporter as potential therapeutic agents for the treatment of cognitive disorders

(+)-Trienomycins A, B, C, and F and (+)-Mycotrienins I and II: Relative and Absolute Stereochemistry

Identification of potent pyrimidine inhibitors of phosphodiesterase 7 (PDE7) and their ability to inhibit T cell proliferation

Understanding Wheel Spinning in the Context of Affective Factors

Fused pyrimidine based inhibitors of phosphodiesterase 7 (PDE7): synthesis and initial structure–activity relationships

Design, Synthesis, and Biological Evaluation of Monopyrrolinone-Based HIV-1 Protease Inhibitors

Identification of purine inhibitors of phosphodiesterase 7 (PDE7)

Complestatin synthetic studies

Complestatin synthetic studies: the effect of the amino acid configuration on peptide backbone conformation in the common western BCD macrocycle

Total Syntheses of (+)-Trienomycins A and F via a Unified Strategy

Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1

Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase

Synthesis and Biological Activity of Cyclic Peptide Inhibitors of Ribonucleotide Reductase

Total Synthesis of (+)-Trienomycins A and F

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