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CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice

Atherosclerosis, 2014-01, Vol.232 (1), p.110-118

2014

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Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA[S]

Journal of lipid research, 2015-03, Vol.56 (3), p.703-712

2015

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HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE-/- Mice: Evidence of ABCA1 Down-Regulation

PloS one, 2015-09, Vol.10 (9), p.e0137584-e0137584

2015

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The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus

Journal of hepatology, 2007-03, Vol.46 (3), p.411-419

2007

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Ecto-F1Fo ATP synthase/F1 ATPase: metabolic and immunological functions

Current opinion in lipidology, 2006-06, Vol.17 (3), p.279-284

2006

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P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo

PloS one, 2014-04, Vol.9 (4), p.e95807-e95807

2014

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Accelerated Lipid Absorption in Mice Overexpressing Intestinal SR-BI

The Journal of biological chemistry, 2006-03, Vol.281 (11), p.7214-7219

2006

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Hepatic lipase:structure/function relationship, synthesis,and regulation

Journal of lipid research, 2002-08, Vol.43 (8), p.1163-1169

2002

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Effects of human follicular fluid and high-density lipoproteins on early spermatozoa hyperactivation and cholesterol efflux

Journal of lipid research, 2010-06, Vol.51 (6), p.1363-1369

2010

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Non-clinical development of CER-001

Frontiers in pharmacology, 2015-10, Vol.6, p.220-220

Barbaras, Ronald

2015

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MO287: A Recombinant BIO-HDL (CER-001) Can Prevent SARS-COV2-Induced Renal Dysfunction by Restoring SR-BI Signalling

Nephrology, dialysis, transplantation, 2022-05, Vol.37 (Supplement_3)

2022

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Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I

Journal of lipid research, 1999-07, Vol.40 (7), p.1185-1193

1999

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CER-001 ameliorates lipid profile and kidney disease in a mouse model of familial LCAT deficiency

Metabolism, clinical and experimental, 2021-03, Vol.116, p.154464-154464, Article 154464

2021

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RhoB Prenylation Is Driven by the Three Carboxyl-Terminal Amino Acids of the Protein: Evidenced in vivo by an Anti-Farnesyl Cysteine Antibody

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (21), p.11626-11631

2000

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Development of CER-001: Preclinical Dose Selection Through to Phase I Clinical Findings

Clinical drug investigation, 2017-05, Vol.37 (5), p.483-491

2017

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Coupled assay of sphingomyelin and ceramide molecular species by gas liquid chromatography

Journal of lipid research, 2002-03, Vol.43 (3), p.510-522

2002

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Tumor Recognition following Vγ9Vδ2 T Cell Receptor Interactions with a Surface F1-ATPase-Related Structure and Apolipoprotein A-I

Immunity (Cambridge, Mass.), 2005, Vol.22 (1), p.71-80

2005

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HDL mimetic CER-001 targets atherosclerotic plaques in patients

Atherosclerosis, 2016-08, Vol.251, p.381-388

2016

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Enterophilin-1, a New Partner of Sorting Nexin 1, Decreases Cell Surface Epidermal Growth Factor Receptor

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.21155-21161

2003

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Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis

Nature (London), 2003-01, Vol.421 (6918), p.75-79

2003

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HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE.sup.-/- Mice: Evidence of ABCA1 Down-Regulation

PloS one, 2015-09, Vol.10 (9)

2015

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High-Density Lipoprotein 3 Receptor-Dependent Endocytosis Pathway in a Human Hepatoma Cell Line (HepG2)

Biochemistry (Easton), 1996-10, Vol.35 (40), p.13064-13071

1996

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RhoA/ROCK I signalling downstream of the P2Y13 ADP-receptor controls HDL endocytosis in human hepatocytes

Cellular signalling, 2009-01, Vol.21 (1), p.120-127

2009

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Abstract 18667: Anti-atherosclerotic Effect of CER-001, an Engineered HDL-mimetic, in the High-fat Diet-fed LDLr Knockout Mice

Circulation (New York, N.Y.), 2012-11, Vol.126 (suppl_21)

2012

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CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice

Beneficial effects of recombinant CER-001 high-density lipoprotein infusion in sepsis: results from a bench to bedside translational research project

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA[S]

HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE-/- Mice: Evidence of ABCA1 Down-Regulation

The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus

Ecto-F1Fo ATP synthase/F1 ATPase: metabolic and immunological functions

P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo

Accelerated Lipid Absorption in Mice Overexpressing Intestinal SR-BI

Hepatic lipase:structure/function relationship, synthesis,and regulation

Effects of human follicular fluid and high-density lipoproteins on early spermatozoa hyperactivation and cholesterol efflux

Non-clinical development of CER-001

MO287: A Recombinant BIO-HDL (CER-001) Can Prevent SARS-COV2-Induced Renal Dysfunction by Restoring SR-BI Signalling

Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I

CER-001 ameliorates lipid profile and kidney disease in a mouse model of familial LCAT deficiency

RhoB Prenylation Is Driven by the Three Carboxyl-Terminal Amino Acids of the Protein: Evidenced in vivo by an Anti-Farnesyl Cysteine Antibody

Development of CER-001: Preclinical Dose Selection Through to Phase I Clinical Findings

Coupled assay of sphingomyelin and ceramide molecular species by gas liquid chromatography

Tumor Recognition following Vγ9Vδ2 T Cell Receptor Interactions with a Surface F1-ATPase-Related Structure and Apolipoprotein A-I

HDL mimetic CER-001 targets atherosclerotic plaques in patients

Enterophilin-1, a New Partner of Sorting Nexin 1, Decreases Cell Surface Epidermal Growth Factor Receptor

Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis

HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE.sup.-/- Mice: Evidence of ABCA1 Down-Regulation

High-Density Lipoprotein 3 Receptor-Dependent Endocytosis Pathway in a Human Hepatoma Cell Line (HepG2)

RhoA/ROCK I signalling downstream of the P2Y13 ADP-receptor controls HDL endocytosis in human hepatocytes

Abstract 18667: Anti-atherosclerotic Effect of CER-001, an Engineered HDL-mimetic, in the High-fat Diet-fed LDLr Knockout Mice

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