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Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling

Scientific reports, 2022-07, Vol.12 (1), p.12146-12146, Article 12146

2022

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Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors

PLoS pathogens, 2023-12, Vol.19 (12), p.e1011849-e1011849

2023

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Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA

Frontiers in immunology, 2023-11, Vol.14, p.1290585-1290585

2023

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Synthesis and Biological Evaluation of Structurally Diverse Benzimidazole Scaffolds as Potential Chemotherapeutic Agents

Anti-cancer agents in medicinal chemistry, 2020-01, Vol.20 (3), p.301

2020

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Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells

Frontiers in bioscience (Landmark. Print), 2023-10, Vol.28 (10), p.268-268

2023

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An efficient one-pot conversion of carboxylic acids into benzimidazoles via an HBTU-promoted methodology

RSC advances, 2018-01, Vol.8 (62), p.35824-35830

2018

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Protein citrullination: inhibition, identification and insertion

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2023-11, Vol.378 (1890), p.20220240

2023

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SARM1, an Enzyme Involved in Axon Degeneration, Catalyzes Multiple Activities through a Ternary Complex Mechanism

Biochemistry (Easton), 2023-07, Vol.62 (13), p.2065-2078

2023

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Tyrosine kinase inhibitor conjugated quantum dots for non-small cell lung cancer (NSCLC) treatment

European journal of pharmaceutical sciences, 2019-05, Vol.133, p.145-159

2019

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An efficient one-pot conversion of carboxylic acids into benzimidazoles via an HBTU-promoted methodologyElectronic supplementary information (ESI) available: NMR spectra available for all compounds reported. See DOI: 10.1039/c8ra07773h

2018-10

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Development of LB244, an Irreversible STING Antagonist

Journal of the American Chemical Society, 2023-09, Vol.145 (37), p.20273-20288

2023

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Targeting STING oligomerization with small-molecule inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (33), p.e2305420120-e2305420120

2023

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An Efficient Chemo‐Selective N‐Alkylation Methodology for the Structure Diversification of Indolylbenzimidazoles

ChemistrySelect (Weinheim), 2020-03, Vol.5 (11), p.3173-3178

2020

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Chemical Synthesis and Biological Evaluation of Benzimidazoles as Chemotherapeutics

Barasa, Leonard

2020

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Chemical Derivatization Leads to the Discovery Of Novel Analogs of Azotochelin, a Natural Siderophore, as Promising Anticancer Agents

ChemMedChem, 2024-07, Vol.19 (13), p.e202300715-n/a

2024

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Benzimidazole scaffolds as potential anticancer agents: Synthesis and Biological evaluation

The FASEB journal, 2019-04, Vol.33 (S1), p.646.18-646.18

2019

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4′-Prenyloxyderrone from the stem bark of Millettia oblata ssp. teitensis and the antiplasmodial activities of isoflavones from some Millettia species

Phytochemistry letters, 2014-05, Vol.8, p.69-72

2014

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Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21

PloS one, 2022-10, Vol.17 (10), p.e0265478-e0265478

2022

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Marburg virus disease outbreak in Kween District Uganda, 2017: Epidemiological and laboratory findings

PLoS neglected tropical diseases, 2019-03, Vol.13 (3), p.e0007257-e0007257

2019

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Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya

Clinical infectious diseases, 2022-01, Vol.74 (2), p.288-293

2022

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Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya

Wellcome open research, 2022, Vol.7, p.69-69

2022

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Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21

PloS one, 2022-01, Vol.17 (10), p.e0265478

2022

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Abstract 13143: Long Term Outcomes and Factors Associated With Mortality in Patients With Moderate to Severe Pulmonary Hypertension in Kenya

Circulation (New York, N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A13143-A13143

2018

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Abstract 14912: A Randomized Trial Using Mobile Short-Text Messaging to Improve Cardiovascular Risk Profile in Poorly Controlled Diabetes in Kenya

Circulation (New York, N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A14912-A14912

2018

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Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling

Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors

Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA

Synthesis and Biological Evaluation of Structurally Diverse Benzimidazole Scaffolds as Potential Chemotherapeutic Agents

Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells

An efficient one-pot conversion of carboxylic acids into benzimidazoles via an HBTU-promoted methodology

Protein citrullination: inhibition, identification and insertion

SARM1, an Enzyme Involved in Axon Degeneration, Catalyzes Multiple Activities through a Ternary Complex Mechanism

Tyrosine kinase inhibitor conjugated quantum dots for non-small cell lung cancer (NSCLC) treatment

An efficient one-pot conversion of carboxylic acids into benzimidazoles via an HBTU-promoted methodologyElectronic supplementary information (ESI) available: NMR spectra available for all compounds reported. See DOI: 10.1039/c8ra07773h

Development of LB244, an Irreversible STING Antagonist

Targeting STING oligomerization with small-molecule inhibitors

An Efficient Chemo‐Selective N‐Alkylation Methodology for the Structure Diversification of Indolylbenzimidazoles

Chemical Synthesis and Biological Evaluation of Benzimidazoles as Chemotherapeutics

Chemical Derivatization Leads to the Discovery Of Novel Analogs of Azotochelin, a Natural Siderophore, as Promising Anticancer Agents

Benzimidazole scaffolds as potential anticancer agents: Synthesis and Biological evaluation

4′-Prenyloxyderrone from the stem bark of Millettia oblata ssp. teitensis and the antiplasmodial activities of isoflavones from some Millettia species

Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21

Marburg virus disease outbreak in Kween District Uganda, 2017: Epidemiological and laboratory findings

Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study

Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya

Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21

Abstract 13143: Long Term Outcomes and Factors Associated With Mortality in Patients With Moderate to Severe Pulmonary Hypertension in Kenya

Abstract 14912: A Randomized Trial Using Mobile Short-Text Messaging to Improve Cardiovascular Risk Profile in Poorly Controlled Diabetes in Kenya

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