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Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (22), p.7827-7832

2008

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Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

Virology (New York, N.Y.), 2008-11, Vol.381 (2), p.194-202

2008

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High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines

Molecular therapy, 2010-12, Vol.18 (12), p.2048-2056

2010

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A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis

Molecular therapy, 2007-07, Vol.15 (7), p.1323-1330

2007

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High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy

Human gene therapy, 2010-11, Vol.21 (11), p.1527-1543

2010

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Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3

Human gene therapy, 2010-12, Vol.21 (12), p.1741-1747

2010

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Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo

Cytotherapy (Oxford, England), 2013-08, Vol.15 (8), p.986-998

2013

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Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity

Human gene therapy, 2007-02, Vol.18 (2), p.171-182

2007

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Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses

Human gene therapy, 2010-03, Vol.21 (3), p.271-283

2010

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A simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo

Human gene therapy, 2011-05, Vol.22 (5), p.633-640

2011

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Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

Molecular therapy, 2011-02, Vol.19 (2), p.293-301

2011

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Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5

Human gene therapy, 2006-03, Vol.17 (3), p.321-333

2006

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91. Development of Optimized [“Opt”] AAV Vectors by Combining Capsid-Modified NextGen and Genome-Modified GenX AAV Vectors for High-Efficiency Transduction at Further Reduced Doses

Molecular therapy, 2016-05, Vol.24, p.S39-S40

2016

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Update on Pneumocystis carinii f. sp. hominis typing based on nucleotide sequence variations in internal transcribed spacer regions of rRNA genes

Journal of clinical microbiology, 1998-03, Vol.36 (3), p.734-741

1998

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Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses

Human gene therapy. Part B. Methods, 2016-08, Vol.27 (4), p.143-149

2016

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Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo

Journal of virology, 2015-01, Vol.89 (2), p.952-961

2015

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310. Development of Generation X Recombinant AAV Vectors for Human Gene Therapy

Molecular therapy, 2015-05, Vol.23, p.S125-S125

2015

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Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo

Human gene therapy. Part B. Methods, 2015-12, Vol.26 (6), p.211-220

2015

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High-efficiency transduction of liver cancer cells by recombinant adeno-associated virus serotype 3 vectors

Journal of visualized experiments, 2011-03 (49)

2011

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Internal Transcribed Spacer Regions of rRNA Genes of Pneumocystis carinii from Monkeys

Clinical and Diagnostic Laboratory Immunology, 2001-05, Vol.8 (3), p.503-508

2001

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Optimizing the transduction efficiency of human hematopoietic stem cells using capsid-modified AAV6 vectors in vitro and in a xenograft mouse model in vivo

Cytotherapy (Oxford, England), 2013-08, Vol.15 (8), p.986-998

2013

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8. Adeno-Associated Virus 2-Mediated Gene Transfer: A Complex Interaction between Epidermal Growth Factor Receptor Protein Tyrosine Kinase Signaling and Ubiquitin/Proteasome Pathway in Transgene Expression

Molecular therapy, 2006-05, Vol.13 (S1), p.S3-S4

2006

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A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis

Molecular therapy, 2007-07, Vol.15 (7), p.1323-1330

2007

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High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors

Journal of visualized experiments, 2011-03 (49)

2011

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The Adeno-Associated Virus Genome Packaging Puzzle

Journal of molecular and genetic medicine, 2015-08, Vol.9 (3)

2015

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Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines

A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis

High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3

Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo

Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity

Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses

A simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo

Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5

91. Development of Optimized [“Opt”] AAV Vectors by Combining Capsid-Modified NextGen and Genome-Modified GenX AAV Vectors for High-Efficiency Transduction at Further Reduced Doses

Update on Pneumocystis carinii f. sp. hominis typing based on nucleotide sequence variations in internal transcribed spacer regions of rRNA genes

Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses

Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo

310. Development of Generation X Recombinant AAV Vectors for Human Gene Therapy

Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo

High-efficiency transduction of liver cancer cells by recombinant adeno-associated virus serotype 3 vectors

Internal Transcribed Spacer Regions of rRNA Genes of Pneumocystis carinii from Monkeys

Optimizing the transduction efficiency of human hematopoietic stem cells using capsid-modified AAV6 vectors in vitro and in a xenograft mouse model in vivo

8. Adeno-Associated Virus 2-Mediated Gene Transfer: A Complex Interaction between Epidermal Growth Factor Receptor Protein Tyrosine Kinase Signaling and Ubiquitin/Proteasome Pathway in Transgene Expression

A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis

High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors

The Adeno-Associated Virus Genome Packaging Puzzle

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