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Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts

Nature communications, 2024-08, Vol.15 (1), p.6909-9, Article 6909

2024

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Cysteine‐Specific Multifaceted Bioconjugation of Peptides and Proteins Using 5‐Substituted 1,2,3‐Triazines

Advanced science, 2024-06, Vol.11 (21), p.e2308491-n/a

2024

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Efficient Catalytic Kinetic Resolution of Spiro‐epoxyoxindoles with Concomitant Asymmetric Friedel–Crafts Alkylation of Indoles

Angewandte Chemie (International ed.), 2017-05, Vol.56 (19), p.5332-5335

International ed. in English, 2017

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Michael Addition Reaction between Dehydroalanines and Phosphites Enabled the Introduction of Phosphonates into Oligopeptides

Organic letters, 2024-06, Vol.26 (22), p.4767-4772

2024

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Chiral Phosphoric Acid Catalyzed Asymmetric Oxidative Dearomatization of Naphthols with Quinones

Organic letters, 2016-10, Vol.18 (20), p.5288-5291

2016

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Catalytic Kinetic Resolution of Spiro-Epoxyoxindoles with 1‑Naphthols: Switchable Asymmetric Tandem Dearomatization/Oxa-Michael Reaction and Friedel–Crafts Alkylation of 1‑Naphthols at the C4 Position

ACS catalysis, 2018-03, Vol.8 (3), p.1810-1816

2018

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Enantioselective Dearomative Arylation of Isoquinolines

ACS catalysis, 2016-08, Vol.6 (8), p.5290-5294

2016

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NDTP Mediated Direct Rapid Amide and Peptide Synthesis without Epimerization

Organic letters, 2022-02, Vol.24 (5), p.1169-1174

2022

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Late-stage peptide modification and macrocyclization enabled by tertiary amine catalyzed tryptophan allylation

Chemical science (Cambridge), 2024-07, Vol.15 (28), p.1199-1117

2024

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A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE−/− mice

British journal of pharmacology, 2020-10, Vol.177 (20), p.4627-4644

2020

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1,3‐Dipolar Cycloaddition between Dehydroalanines and C,N‐Cyclic Azomethine Imines: Application to Late‐Stage Peptide Modification

Angewandte Chemie International Edition, 2021-03, Vol.60 (10), p.5331-5338

International ed. in English, 2021

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Access to α,γ-Diamino Diacid Derivatives via Organocatalytic Asymmetric 1,4-Addition of Azlactones and Dehydroalanines

Organic letters, 2018-11, Vol.20 (22), p.7080-7084

2018

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Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site

Organic letters, 2022-12, Vol.24 (50), p.9248-9253

2022

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Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy

Biochemical pharmacology, 2024-07, Vol.225, p.116269, Article 116269

2024

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Visible-Light Mediated Deoxygenation of Carboxylic Acid for Late-Stage Peptide Modification Targeting Dehydroalanine

Organic letters, 2023-11, Vol.25 (46), p.8338-8343

2023

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Regio- and stereoselective ring-opening reaction of spiro-epoxyoxindoles with ammonia under catalyst-free conditions

Green chemistry : an international journal and green chemistry resource : GC, 2017, Vol.19 (9), p.2107-2110

2017

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Catalyst-controlled switch of regioselectivity in the asymmetric allylic alkylation of oxazolones with MBHCs

Chemical communications (Cambridge, England), 2016-01, Vol.52 (50), p.7882-7885

2016

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Switchable Skeletal Rearrangement of Dihydroisobenzofuran Acetals with Indoles

Organic letters, 2019-06, Vol.21 (11), p.4313-4317

2019

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Regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindolesElectronic supplementary information (ESI) available: Details of the experimental procedure, data, HPLC and NMR spectra of all compounds. See DOI: 10.1039/c8ob00861b

2018-05

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Regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindoles

Organic & biomolecular chemistry, 2018, Vol.16 (19), p.3655-3661

2018

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NaClO‐Mediated Cross Installation of Indoles and Azoles Benefits Anticancer Hit Discovery

ChemMedChem, 2023-03, Vol.18 (5), p.e202200651-n/a

2023

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Regio- and stereoselective ring-opening reaction of spiro-epoxyoxindoles with ammonia under catalyst-free conditionsElectronic supplementary information (ESI) available: Details of the experimental procedure, data, HPLC and NMR spectra of all compounds. See DOI: 10.1039/c7gc00438a

2017-05

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Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis

ACS pharmacology & translational science, 2024-04, Vol.7 (4), p.1126-1141

2024

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Catalyst-controlled switch of regioselectivity in the asymmetric allylic alkylation of oxazolones with MBHCsElectronic supplementary information (ESI) available: Details of the experimental procedure, data, HPLC and NMR spectra of all compounds. CCDC 1451071 (3ac′) and 1451084 (4ca). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6cc03246j

2016-06

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1,3‐Dipolar Cycloaddition between Dehydroalanines and C,N‐Cyclic Azomethine Imines: Application to Late‐Stage Peptide Modification

Angewandte Chemie, 2021-03, Vol.133 (10), p.5391-5398

2021

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Orthogonal bioconjugation targeting cysteine-containing peptides and proteins using alkyl thianthrenium salts

Cysteine‐Specific Multifaceted Bioconjugation of Peptides and Proteins Using 5‐Substituted 1,2,3‐Triazines

Efficient Catalytic Kinetic Resolution of Spiro‐epoxyoxindoles with Concomitant Asymmetric Friedel–Crafts Alkylation of Indoles

Michael Addition Reaction between Dehydroalanines and Phosphites Enabled the Introduction of Phosphonates into Oligopeptides

Chiral Phosphoric Acid Catalyzed Asymmetric Oxidative Dearomatization of Naphthols with Quinones

Catalytic Kinetic Resolution of Spiro-Epoxyoxindoles with 1‑Naphthols: Switchable Asymmetric Tandem Dearomatization/Oxa-Michael Reaction and Friedel–Crafts Alkylation of 1‑Naphthols at the C4 Position

Enantioselective Dearomative Arylation of Isoquinolines

NDTP Mediated Direct Rapid Amide and Peptide Synthesis without Epimerization

Late-stage peptide modification and macrocyclization enabled by tertiary amine catalyzed tryptophan allylation

A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE−/− mice

1,3‐Dipolar Cycloaddition between Dehydroalanines and C,N‐Cyclic Azomethine Imines: Application to Late‐Stage Peptide Modification

Access to α,γ-Diamino Diacid Derivatives via Organocatalytic Asymmetric 1,4-Addition of Azlactones and Dehydroalanines

Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site

Enhancing the stability and therapeutic potential of the antimicrobial peptide Feleucin-K3 against Multidrug-Resistant a. Baumannii through rational utilization of a D-amino acid substitution strategy

Visible-Light Mediated Deoxygenation of Carboxylic Acid for Late-Stage Peptide Modification Targeting Dehydroalanine

Regio- and stereoselective ring-opening reaction of spiro-epoxyoxindoles with ammonia under catalyst-free conditions

Catalyst-controlled switch of regioselectivity in the asymmetric allylic alkylation of oxazolones with MBHCs

Switchable Skeletal Rearrangement of Dihydroisobenzofuran Acetals with Indoles

Regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindolesElectronic supplementary information (ESI) available: Details of the experimental procedure, data, HPLC and NMR spectra of all compounds. See DOI: 10.1039/c8ob00861b

Regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindoles

NaClO‐Mediated Cross Installation of Indoles and Azoles Benefits Anticancer Hit Discovery

Regio- and stereoselective ring-opening reaction of spiro-epoxyoxindoles with ammonia under catalyst-free conditionsElectronic supplementary information (ESI) available: Details of the experimental procedure, data, HPLC and NMR spectra of all compounds. See DOI: 10.1039/c7gc00438a

Novel Peptide DR3penA as a Low-Toxicity Antirenal Fibrosis Agent by Suppressing the TGF-β1/miR-212-5p/Low-Density Lipoprotein Receptor Class a Domain Containing 4/Smad Axis

1,3‐Dipolar Cycloaddition between Dehydroalanines and C,N‐Cyclic Azomethine Imines: Application to Late‐Stage Peptide Modification

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