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Lessons from mouse models of Graves’ disease

Endocrine, 2020-05, Vol.68 (2), p.265-270

2020

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Modeling Graves' Orbitopathy in Experimental Graves' Disease

Hormone and metabolic research, 2015-09, Vol.47 (10), p.797-803

2015

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Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes

Diabetologia, 2005-05, Vol.48 (5), p.922-930

2005

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Autoimmune Thyroid Diseases

Hormone and metabolic research, 2015-09, Vol.47 (10), p.699-701

2015

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Genetic immunization with mouse thyrotrophin hormone receptor plasmid breaks self‐tolerance for a murine model of autoimmune thyroid disease and Graves' orbitopathy

Clinical and experimental immunology, 2018-03, Vol.191 (3), p.255-267

2018

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Superiority of thyroid peroxidase DNA over protein immunization in replicating human thyroid autoimmunity in HLA‐DRB10301 (DR3) transgenic mice

Clinical and experimental immunology, 2004-09, Vol.137 (3), p.503-512

2004

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Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis

Clinical and experimental immunology, 2004-04, Vol.136 (1), p.137-144

2004

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Autoantibody epitopes to the smaller isoform of glutamate decarboxylase do not differ in Swedish and Japanese type 1 diabetes patients and may be associated with high-risk human leucocyte antigen class II alleles

Clinical and experimental immunology, 2007-12, Vol.150 (3), p.416-421

2007

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Graves’ hyperthyroidism and thyroiditis in HLA‐DRB10301 (DR3) transgenic mice after immunization with thyrotropin receptor DNA

Clinical and experimental immunology, 2004-01, Vol.135 (1), p.35-40

2004

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Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient

Clinical and experimental immunology, 2004-01, Vol.135 (1), p.74-84

2004

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Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor

Clinical and experimental immunology, 2004-06, Vol.136 (3), p.413-422

2004

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Multiplicity of the antibody response to GAD65 in Type I diabetes

Clinical and experimental immunology, 2004-11, Vol.138 (2), p.337-341

2004

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Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders

Clinical and experimental immunology, 1999-12, Vol.118 (3), p.349-356

1999

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The development of new density gradient media for purifying human islets and islet-quality assessments

Transplantation, 2004-01, Vol.77 (1), p.143-145

2004

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Two amino acids in glutamic acid decarboxylase act in concert for maintainance of conformational determinants recognised by Type I diabetic autoantibodies

Diabetologia, 2000-07, Vol.43 (7), p.881-889

2000

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Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells

Journal of molecular endocrinology, 1996-04, Vol.16 (2), p.159-170

1996

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Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a nondiabetic patient with multiple autoantibodies and Graves' disease : A comparison with those present in type 1 diabetes

The journal of clinical endocrinology and metabolism, 1997-08, Vol.82 (8), p.2664-2670

1997

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Human thyroid peroxidase (TPO) isoforms, TPO-1 and TPO-2: Analysis of protein expression in Graves' thyroid tissue

The journal of clinical endocrinology and metabolism, 1997-11, Vol.82 (11), p.3752-3757

1997

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Role of complex asparagine-linked oligosaccharides in the expression of a functional thyrotropin receptor

Biochemical journal, 2001-03, Vol.354 (Pt 2), p.331-336

2001

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Parathyroid hormone-related peptide in normal human fetal development

Journal of molecular endocrinology, 1990-12, Vol.5 (3), p.259-266

1990

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The thyrotrophin hormone receptor of Graves' disease: overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding

Journal of molecular endocrinology, 1993-04, Vol.10 (2), p.127-142

1993

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Induction of thyroiditis in mice with thyrotropin receptor lacking serologically dominant regions

Clinical and experimental immunology, 1998-07, Vol.113 (1), p.119-125

1998

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Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: implications for the establishment of a mouse model for Graves’ disease

Clinical and experimental immunology, 1995-02, Vol.99 (2), p.294-302

1995

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Purification and Crystallisation of the Autoantigen Thyroid Peroxidase from Human Graves’ Thyroid Tissue

Biochemical and biophysical research communications, 1997-05, Vol.234 (2), p.366-370

1997

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Evidence for recognition of novel islet T cell antigens by granule‐specific T cell lines from new onset type 1 diabetic patients

Clinical and experimental immunology, 2000-07, Vol.121 (1), p.100-105

2000

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Lessons from mouse models of Graves’ disease

Modeling Graves' Orbitopathy in Experimental Graves' Disease

Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes

Autoimmune Thyroid Diseases

Genetic immunization with mouse thyrotrophin hormone receptor plasmid breaks self‐tolerance for a murine model of autoimmune thyroid disease and Graves' orbitopathy

Superiority of thyroid peroxidase DNA over protein immunization in replicating human thyroid autoimmunity in HLA‐DRB10301 (DR3) transgenic mice

Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis

Autoantibody epitopes to the smaller isoform of glutamate decarboxylase do not differ in Swedish and Japanese type 1 diabetes patients and may be associated with high-risk human leucocyte antigen class II alleles

Graves’ hyperthyroidism and thyroiditis in HLA‐DRB10301 (DR3) transgenic mice after immunization with thyrotropin receptor DNA

Modulation of antigen presentation by autoreactive B cell clones specific for GAD65 from a type I diabetic patient

Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor

Multiplicity of the antibody response to GAD65 in Type I diabetes

Comparative analysis of epitope recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different autoimmune disorders

The development of new density gradient media for purifying human islets and islet-quality assessments

Two amino acids in glutamic acid decarboxylase act in concert for maintainance of conformational determinants recognised by Type I diabetic autoantibodies

Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells

Human B cells secreting immunoglobulin G to glutamic acid decarboxylase-65 from a nondiabetic patient with multiple autoantibodies and Graves' disease : A comparison with those present in type 1 diabetes

Human thyroid peroxidase (TPO) isoforms, TPO-1 and TPO-2: Analysis of protein expression in Graves' thyroid tissue

Role of complex asparagine-linked oligosaccharides in the expression of a functional thyrotropin receptor

Parathyroid hormone-related peptide in normal human fetal development

The thyrotrophin hormone receptor of Graves' disease: overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding

Induction of thyroiditis in mice with thyrotropin receptor lacking serologically dominant regions

Unaltered thyroid function in mice responding to a highly immunogenic thyrotropin receptor: implications for the establishment of a mouse model for Graves’ disease

Purification and Crystallisation of the Autoantigen Thyroid Peroxidase from Human Graves’ Thyroid Tissue

Evidence for recognition of novel islet T cell antigens by granule‐specific T cell lines from new onset type 1 diabetic patients

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