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Immune regulation by Tim-3

F1000 research, 2018, Vol.7, p.316-316

2018

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The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Science signaling, 2021-06, Vol.14 (687)

2021

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Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment

Cell reports (Cambridge), 2021-09, Vol.36 (11), p.109699-109699, Article 109699

2021

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Tim-3 mediates T cell trogocytosis to limit antitumor immunity

The Journal of clinical investigation, 2022-05, Vol.132 (9), p.1-15

2022

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1026 PIK3IP1/TrIP immune regulation on CD8+ T cells restricts anti-tumor immunity

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1134-A1134

2023

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692 Tim-3 expression drives phenotypic and functional changes in Treg in secondary lymphoid organs and the tumor microenvironment, effecting tumor burden

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A720-A720

2021

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1003 TIM-3+ natural killer cell dysfunction is driven by galectin-9 in head and neck squamous cell carcinoma

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1111-A1111

2023

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Tim-3 expression in Treg controls viral persistence and effector T cell response during chronic LCMV infection

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.236-236.03

2023

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Tim-3 deletion on Treg increases virus-specific T cell response and reduces viral burden in chronic LCMV infection

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.110-110.13

2022

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Enhanced suppressive phenotype of Tim-3+ Treg during chronic infection

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.96-96.06

2021

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Mechanism of Tim-3 regulation of CD8+ T cell function

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.55-55.04

2022

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TIM-3+ T regulatory cells alter the lymphoid compartment in cold and Hot solid tumor Model

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.180-180.05

2022

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PIK3IP1/TrIP Immune Regulation on CD8+ T Cells Restricts Anti-Tumor Immunity

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.121-121.11

2022

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Elucidating the roles of PIK3IP1/TrIP in PI3-kinase regulation, T cell differentiation and T cell function in vivo

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.57-57.24

2021

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Expression of Tim-3 drives Treg to an effector-like state with enhanced suppressive activity and altered response to tumor

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.57-57.19

2021

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Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC and metalloprotease-mediated cleavage

The Journal of biological chemistry, 2024-10, p.107930, Article 107930

2024

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1020 Targeting TIM-3 on T regulatory cells make nonresponsive cold melanoma, more responsive to immune mediated tumor control

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A1063-A1063

2022

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Tim-3 Is Required for Regulatory T Cell–Mediated Promotion of T Cell Exhaustion and Viral Persistence during Chronic Lymphocytic Choriomeningitis Virus Infection

The Journal of immunology (1950), 2024-09

2024

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Association of Mast Cell Burden and TIM-3 Expression with Recalcitrant Chronic Rhinosinusitis with Nasal Polyps

Annals of otology, rhinology & laryngology, 2021-09, Vol.130 (9), p.1069-1077

2021

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Functionally significant metabolic differences between B and T lymphocyte lineages

Immunology, 2019-10, Vol.158 (2), p.104-120

2019

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A role for apoptosis-inducing factor in T cell development

The Journal of experimental medicine, 2012-08, Vol.209 (9), p.1641-1653

2012

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Role of apoptosis-inducing factor (Aif) in the T cell lineage

Indian journal of medical research (New Delhi, India : 1994), 2013-11, Vol.138 (5), p.577-590

2013

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Apoptosis-Inducing Factor Regulates Death in Peripheral T Cells

Journal of Immunology, 2007-07, Vol.179 (2), p.797-803

2007

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Immune regulation by Tim-3

The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse

Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment

Tim-3 mediates T cell trogocytosis to limit antitumor immunity

1026 PIK3IP1/TrIP immune regulation on CD8+ T cells restricts anti-tumor immunity

692 Tim-3 expression drives phenotypic and functional changes in Treg in secondary lymphoid organs and the tumor microenvironment, effecting tumor burden

1003 TIM-3+ natural killer cell dysfunction is driven by galectin-9 in head and neck squamous cell carcinoma

Tim-3 expression in Treg controls viral persistence and effector T cell response during chronic LCMV infection

Tim-3 deletion on Treg increases virus-specific T cell response and reduces viral burden in chronic LCMV infection

Enhanced suppressive phenotype of Tim-3+ Treg during chronic infection

Mechanism of Tim-3 regulation of CD8+ T cell function

TIM-3+ T regulatory cells alter the lymphoid compartment in cold and Hot solid tumor Model

PIK3IP1/TrIP Immune Regulation on CD8+ T Cells Restricts Anti-Tumor Immunity

Elucidating the roles of PIK3IP1/TrIP in PI3-kinase regulation, T cell differentiation and T cell function in vivo

Expression of Tim-3 drives Treg to an effector-like state with enhanced suppressive activity and altered response to tumor

Downregulation of PIK3IP1/TrIP on T cells is controlled by TCR signal strength, PKC and metalloprotease-mediated cleavage

1020 Targeting TIM-3 on T regulatory cells make nonresponsive cold melanoma, more responsive to immune mediated tumor control

Tim-3 Is Required for Regulatory T Cell–Mediated Promotion of T Cell Exhaustion and Viral Persistence during Chronic Lymphocytic Choriomeningitis Virus Infection

Association of Mast Cell Burden and TIM-3 Expression with Recalcitrant Chronic Rhinosinusitis with Nasal Polyps

Functionally significant metabolic differences between B and T lymphocyte lineages

A role for apoptosis-inducing factor in T cell development

Role of apoptosis-inducing factor (Aif) in the T cell lineage

Apoptosis-Inducing Factor Regulates Death in Peripheral T Cells

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