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Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.4896-4933

2012

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Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging

Journal of the American Chemical Society, 2015-09, Vol.137 (35), p.11461-11475

2015

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Synthesis and Antibiofilm Activity of a Second-Generation Reverse-Amide Oroidin Library: A Structure-Activity Relationship Study

Chemistry : a European journal, 2008-11, Vol.14 (34), p.10745-10761

2008

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Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism

Drug metabolism and disposition, 2016-02, Vol.44 (2), p.172-179

2016

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Simplifying the Execution of HepatoPac MetID Experiments: Metabolite Profile and Intrinsic Clearance Comparisons

Drug metabolism and disposition, 2020-09, Vol.48 (9), p.804-810

2020

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Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24‐hydroxylase inhibitor soticlestat in healthy volunteers

British journal of clinical pharmacology, 2024-02, Vol.90 (2), p.516-527

2024

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The Importance of Tracking “Missing” Metabolites: How and Why?

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15586-15612

2023

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An Isotopically Tagged Azobenzene-Based Cleavable Linker for Quantitative Proteomics

Chembiochem : a European journal of chemical biology, 2013-08, Vol.14 (12), p.1410-1414

2013

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Translocation Carcinomas of the Kidney After Chemotherapy in Childhood

Journal of clinical oncology, 2006-04, Vol.24 (10), p.1529-1534

2006

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γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin

The Journal of biological chemistry, 2013-04, Vol.288 (14), p.9710-9720

2013

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Mucociliary transport in porcine trachea: differential effects of inhibiting chloride and bicarbonate secretion

American journal of physiology. Lung cellular and molecular physiology, 2013-02, Vol.304 (3), p.L184-L190

2013

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Microwave-assisted extraction of betalains from red beet (Beta vulgaris)

Food science & technology, 2014-11, Vol.59 (1), p.276-282

2014

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Increased growing temperature reduces content of polyunsaturated fatty acids in four oilseed crops

Industrial crops and products, 2013-11, Vol.51, p.212-219

2013

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Impacts of forest management on northern forest soils

Forest ecology and management, 2000-08, Vol.133 (1), p.37-42

Ballard, T.M.

2000

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Discovery of N‑((3R,4R)‑4-Fluoro-1-(6-((3-methoxy-1-methyl‑1H‑pyrazol-4-yl)amino)-9-methyl‑9H‑purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.3002-3019

2017

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Stem Cells and the Regeneration of the Aging Cardiovascular System

Circulation research, 2007-04, Vol.100 (8), p.1116-1127

2007

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Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues

Organic & biomolecular chemistry, 2008-01, Vol.6 (8), p.1356-1363

2008

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Determination of Antibody–Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric Interrogation

Bioconjugate chemistry, 2016-07, Vol.27 (7), p.1645-1654

2016

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Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans

Xenobiotica, 2022-03, Vol.52 (3), p.240-253

2022

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Development of clickable active site-directed photoaffinity probes for γ-secretase

Bioorganic & medicinal chemistry letters, 2012-04, Vol.22 (8), p.2997-3000

2012

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Inhibition of Pseudomonas aeruginosa Biofilm Formation with Bromoageliferin Analogues

Journal of the American Chemical Society, 2007-06, Vol.129 (22), p.6966-6967

2007

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Natural Product Bis-Intercalator Depsipeptides as a New Class of Payloads for Antibody–Drug Conjugates

Bioconjugate chemistry, 2019-01, Vol.30 (1), p.200-209

2019

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Anticancer effects of lipid encapsulated Bilberry

European journal of cancer (1990), 2016-07, Vol.61, p.S107-S107

2016

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Fluid secretion by submucosal glands of the tracheobronchial airways

Respiratory physiology & neurobiology, 2007-12, Vol.159 (3), p.271-277

2007

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Synthesis and Screening of an Oroidin Library against Pseudomonas aeruginosa Biofilms

Chembiochem : a European journal of chemical biology, 2008-05, Vol.9 (8), p.1267-1279

2008

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