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Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes

Human molecular genetics, 2016-01, Vol.25 (1), p.9-23

2016

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Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation

PloS one, 2012-04, Vol.7 (4), p.e35826-e35826

2012

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One reporter for in-cell activity profiling of majority of protein kinase oncogenes

eLife, 2017-02, Vol.6

2017

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Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

EMBO molecular medicine, 2020-11, Vol.12 (11), p.e11739-n/a

2020

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A novel variant of FGFR3 causes proportionate short stature

European journal of endocrinology, 2015-06, Vol.172 (6), p.763

2015

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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

Oncotarget, 2017-12, Vol.8 (65), p.109319-109331

2017

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Decrease in Abundance of Apurinic/Apyrimidinic Endonuclease Causes Failure of Base Excision Repair in Culture‐Adapted Human Embryonic Stem Cells

Stem cells (Dayton, Ohio), 2013-04, Vol.31 (4), p.693-702

2013

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Effect of FGFR inhibitors on chicken limb development

Development, growth & differentiation, 2014-10, Vol.56 (8), p.555-572

2014

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Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

Biomaterials, 2018-09, Vol.176, p.106-121

2018

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Computer‐assisted engineering of hyperstable fibroblast growth factor 2

Biotechnology and bioengineering, 2018-04, Vol.115 (4), p.850-862

2018

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Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (10), p.4316-4325

2019

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ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

Bone (New York, N.Y.), 2017-12, Vol.105, p.57-66

2017

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An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

Human molecular genetics, 2016-09, Vol.25 (18), p.3998-4011

2016

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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

Cellular signalling, 2018-01, Vol.42, p.144-154

2018

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Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

Biochimica et biophysica acta, 2015-05, Vol.1852 (5), p.839-850

2015

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Cover Image, Volume 115, Number 4, April 2018

Biotechnology and bioengineering, 2018-04, Vol.115 (4)

2018

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Automated cell segmentation in phase-contrast images based on classification and region growing

2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), 2015, p.1447-1451

2015

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IEEE_Xplore

Estimating Drought-Induced Crop Yield Losses at the Cadastral Area Level in the Czech Republic

Agronomy (Basel), 2023-07, Vol.13 (7), p.1669

2023

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Differentiating between artificial and natural sources of electromagnetic radiation at a seismogenic fault

Engineering geology, 2022-12, Vol.311, p.106912, Article 106912

2022

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Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes

Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

One reporter for in-cell activity profiling of majority of protein kinase oncogenes

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

A novel variant of FGFR3 causes proportionate short stature

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

Decrease in Abundance of Apurinic/Apyrimidinic Endonuclease Causes Failure of Base Excision Repair in Culture‐Adapted Human Embryonic Stem Cells

Effect of FGFR inhibitors on chicken limb development

Nanodiamonds as “artificial proteins”: Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals

Computer‐assisted engineering of hyperstable fibroblast growth factor 2

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage

Cover Image, Volume 115, Number 4, April 2018

Automated cell segmentation in phase-contrast images based on classification and region growing

Receptor Tyrosine Kinases Activate Canonical WNT/[beta]-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct [beta]-Catenin Phosphorylation

Estimating Drought-Induced Crop Yield Losses at the Cadastral Area Level in the Czech Republic

Differentiating between artificial and natural sources of electromagnetic radiation at a seismogenic fault

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