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The potential of methioninase for cancer treatment

Biochimica et biophysica acta. Reviews on cancer, 2024-07, Vol.1879 (4), p.189122, Article 189122

2024

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Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane

Bioorganic & medicinal chemistry, 2018-12, Vol.26 (22), p.5824-5837

2018

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Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

BioMed research international, 2016-01, Vol.2016, p.3864193-8

2016

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Kohonen maps for prediction of binding to human cytochrome P450 3A4

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1183

2004

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Nonlinear Dimensionality Reduction for Visualizing Toxicity Data: Distance-Based Versus Topology-Based Approaches

ChemMedChem, 2014-05, Vol.9 (5), p.1047-1059

2014

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Integration of Virtual Screening with High-Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor Antagonists

Molecular pharmacology, 2005-11, Vol.68 (5), p.1301-1310

2005

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Synthesis and Antitumor Activity of Novel Pyridoxine-Based Bioisosteric Analogs of trans-Stilbenes

Journal of chemistry, 2017-01, Vol.2017, p.1-7

2017

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VEGF/VEGFR signalling as a target for inhibiting angiogenesis

Expert opinion on investigational drugs, 2007-01, Vol.16 (1), p.83-107

2007

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Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series

Journal of chemistry, 2018-01, Vol.2018, p.1-14

2018

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Pharmaceutical data mining: approaches and applications for drug discovery

1st ed., 2009

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Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms

Journal of chemistry, 2017-01, Vol.2017, p.1-15

2017

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Antibacterial activity profile of miramistin in in vitro and in vivo models

Microbial pathogenesis, 2020-05, Vol.142, p.104072-104072, Article 104072

2020

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Synthesis, antitumor activity and structure-activity studies of novel pyridoxine-based bioisosteric analogs of estradiol

Bioorganic & medicinal chemistry, 2021-01, Vol.30, p.115957, Article 115957

2021

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Morphological and functional evaluation of the effect of novel pyrimidine derivatives on regeneration of the sciatic nerve in rats

Neuroscience letters, 2019-07, Vol.706, p.110-113

2019

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In silico approaches to prediction of aqueous and DMSO solubility of drug-like compounds: trends, problems and solutions

Current medicinal chemistry, 2006, Vol.13 (2), p.223

2006

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Drug Discovery Using Support Vector Machines. The Case Studies of Drug-likeness, Agrochemical-likeness, and Enzyme Inhibition Predictions

Journal of Chemical Information and Computer Sciences, 2003-11, Vol.43 (6), p.2048-2056

2003

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Novel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (16), p.4092-4094

2016

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Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus

Scientific reports, 2017-11, Vol.7 (1), p.16072-7, Article 16072

2017

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Synthesis, antibacterial and antitumor activity of methylpyridinium salts of pyridoxine functionalized 2-amino-6-sulfanylpyridine-3,5-dicarbonitriles

Synthetic communications, 2018-09, Vol.48 (17), p.2288-2304

2018

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In-vitro antitumor activity of new quaternary phosphonium salts, derivatives of 3-hydroxypyridine

Anti-cancer drugs, 2018-08, Vol.29 (7), p.682-690

2018

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Quantitative structure-metabolism relationship modeling of metabolic N-dealkylation reaction rates

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1111

2004

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Arbidol: a quarter-century after. Past, present and future of the original Russian antiviral

Russian chemical reviews, 2018-06, Vol.87 (6), p.509-552

2018

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Shape Signatures: New Descriptors for Predicting Cardiotoxicity In Silico

Chemical research in toxicology, 2008-06, Vol.21 (6), p.1304-1314

2008

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Synthesis and antitumor activity of novel pyridoxine-based structural analogs of saccharumoside-B

Medicinal chemistry research, 2021-05, Vol.30 (5), p.1139-1150

2021

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Insights for Human Ether-a-Go-Go-Related Gene Potassium Channel Inhibition Using Recursive Partitioning and Kohonen and Sammon Mapping Techniques

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5059-5071

2006

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The potential of methioninase for cancer treatment

Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane

Synthesis and Antibacterial Activity of Quaternary Ammonium 4-Deoxypyridoxine Derivatives

Kohonen maps for prediction of binding to human cytochrome P450 3A4

Nonlinear Dimensionality Reduction for Visualizing Toxicity Data: Distance-Based Versus Topology-Based Approaches

Integration of Virtual Screening with High-Throughput Flow Cytometry to Identify Novel Small Molecule Formylpeptide Receptor Antagonists

Synthesis and Antitumor Activity of Novel Pyridoxine-Based Bioisosteric Analogs of trans-Stilbenes

VEGF/VEGFR signalling as a target for inhibiting angiogenesis

Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series

Pharmaceutical data mining: approaches and applications for drug discovery

Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms

Antibacterial activity profile of miramistin in in vitro and in vivo models

Synthesis, antitumor activity and structure-activity studies of novel pyridoxine-based bioisosteric analogs of estradiol

Morphological and functional evaluation of the effect of novel pyrimidine derivatives on regeneration of the sciatic nerve in rats

In silico approaches to prediction of aqueous and DMSO solubility of drug-like compounds: trends, problems and solutions

Drug Discovery Using Support Vector Machines. The Case Studies of Drug-likeness, Agrochemical-likeness, and Enzyme Inhibition Predictions

Novel potent pyridoxine-based inhibitors of AChE and BChE, structural analogs of pyridostigmine, with improved in vivo safety profile

Pyridoxine dipharmacophore derivatives as potent glucokinase activators for the treatment of type 2 diabetes mellitus

Synthesis, antibacterial and antitumor activity of methylpyridinium salts of pyridoxine functionalized 2-amino-6-sulfanylpyridine-3,5-dicarbonitriles

In-vitro antitumor activity of new quaternary phosphonium salts, derivatives of 3-hydroxypyridine

Quantitative structure-metabolism relationship modeling of metabolic N-dealkylation reaction rates

Arbidol: a quarter-century after. Past, present and future of the original Russian antiviral

Shape Signatures: New Descriptors for Predicting Cardiotoxicity In Silico

Synthesis and antitumor activity of novel pyridoxine-based structural analogs of saccharumoside-B

Insights for Human Ether-a-Go-Go-Related Gene Potassium Channel Inhibition Using Recursive Partitioning and Kohonen and Sammon Mapping Techniques

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