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Transient receptor potential A1 modulators

Current topics in medicinal chemistry, 2011-09, Vol.11 (17), p.2227-2236

2011

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Leucine-rich repeat kinase 2 inhibitors: a review of recent patents (2011 - 2013)

Expert opinion on therapeutic patents, 2014-07, Vol.24 (7), p.745-757

2014

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Synthesis of 6-Substituted Imidazo[4,5-d]pyridazin-7-ones

Heterocycles, 2003-06, Vol.60 (6), p.1329

2003

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Pharmacological characterization of a novel nonpeptide antagonist radioligand, (+/-)-N-[2-methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for corticotropin-releasing factor1 receptors

The Journal of pharmacology and experimental therapeutics, 2003-04, Vol.305 (1), p.57

2003

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Discovery of Novel 6,6-Heterocycles as Transient Receptor Potential Vanilloid (TRPV1) Antagonists

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3330-3348

2010

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Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4359-4363

2010

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Modulators of Transient Receptor Potential Ion Channels

Annual Reports in Medicinal Chemistry, 2010, Vol.45, p.37-53

2010

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Aminoquinazolines as TRPV1 antagonists: Modulation of drug-like properties through the exploration of 2-position substitution

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (16), p.4573-4577

2008

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From arylureas to biarylamides to aminoquinazolines: Discovery of a novel, potent TRPV1 antagonist

Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5217-5221

2006

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Pharmacological Characterization of a Novel Nonpeptide Antagonist Radioligand, (±) -N -[2-Methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1 H -1,2,3-triazolo[4,5- c ]pyridin-4-amine ([ 3 H]SN003) for Corticotropin-Releasing Factor 1 Receptors

The Journal of pharmacology and experimental therapeutics, 2003-04, Vol.305 (1), p.57-69

2003

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2,6‐Diarylhexahydro‐4‐pyridazinols by acid‐catalyzed cyclization of benzaldehyde aryl‐2‐(2‐propenyl)hydrazones

Journal of heterocyclic chemistry, 1996-01, Vol.33 (1), p.213-216

1996

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2,6-Diarylhexahydro-4-pyridazinols by acid-catalyzed cyclization of benzaldehyde aryl-2-(2-propenyl)hydrazones

Journal of heterocyclic chemistry, 1996-01, Vol.33 (1), p.213-216

1996

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Synthesis of 6-Substituted Imidazo[4,5-d]pyridazin-7-ones

ChemInform, 2003-09, Vol.34 (38), p.no-no

2003

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Transient receptor potential A1 modulators

Leucine-rich repeat kinase 2 inhibitors: a review of recent patents (2011 - 2013)

Synthesis of 6-Substituted Imidazo[4,5-d]pyridazin-7-ones

Pharmacological characterization of a novel nonpeptide antagonist radioligand, (+/-)-N-[2-methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for corticotropin-releasing factor1 receptors

Discovery of Novel 6,6-Heterocycles as Transient Receptor Potential Vanilloid (TRPV1) Antagonists

Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites

Modulators of Transient Receptor Potential Ion Channels

Aminoquinazolines as TRPV1 antagonists: Modulation of drug-like properties through the exploration of 2-position substitution

From arylureas to biarylamides to aminoquinazolines: Discovery of a novel, potent TRPV1 antagonist

Non-Peptide Corticotropin-Releasing Hormone Antagonists: Syntheses and Structure−Activity Relationships of 2-Anilinopyrimidines and -triazines

Synthesis, Corticotropin-Releasing Factor Receptor Binding Affinity, and Pharmacokinetic Properties of Triazolo-, Imidazo-, and Pyrrolopyrimidines and -pyridines

Pharmacological Characterization of a Novel Nonpeptide Antagonist Radioligand, (±) -N -[2-Methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1 H -1,2,3-triazolo[4,5- c ]pyridin-4-amine ([ 3 H]SN003) for Corticotropin-Releasing Factor 1 Receptors

2,6‐Diarylhexahydro‐4‐pyridazinols by acid‐catalyzed cyclization of benzaldehyde aryl‐2‐(2‐propenyl)hydrazones

2,6-Diarylhexahydro-4-pyridazinols by acid-catalyzed cyclization of benzaldehyde aryl-2-(2-propenyl)hydrazones

Synthesis of 6-Substituted Imidazo[4,5-d]pyridazin-7-ones

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