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Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents

Bioorganic chemistry, 2017-10, Vol.74, p.82-90

2017

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Facile One-Pot Multicomponent Synthesis of Pyrazolo-Thiazole Substituted Pyridines with Potential Anti-Proliferative Activity: Synthesis, In Vitro and In Silico Studies

Molecules (Basel, Switzerland), 2021-05, Vol.26 (11), p.3103

2021

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New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.708

2021

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Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (10), p.1389

2017

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Design, Synthesis, Docking Study of Pyrazolohydrazinopyrimidin‐4‐one Derivatives and Their Application as Antimicrobials

Chemistry & biodiversity, 2023-05, Vol.20 (5), p.e202201209-n/a

2023

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Antioxidant, Antimicrobial, and Molecular Docking Studies of Novel Chalcones and Schiff Bases Bearing 1, 4-naphthoquinone Moiety

Letters in drug design & discovery, 2022-07, Vol.19 (7), p.654-673

2022

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Nitric Oxide-NASIDS Donor Prodrugs as Hybrid Safe Anti-inflammatory Agents

Current topics in medicinal chemistry, 2017-01, Vol.17 (8), p.941-955

2017

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Novel 1,2-Thiazine-Pyridine Hybrid: Design, Synthesis, Antioxidant Activity and Molecular Docking Study

Letters in drug design & discovery, 2022-08, Vol.19 (8), p.675-690

2022

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Efficient and Recoverable Bio-Organic Catalyst Cysteine for Synthesis, Docking Study, and Antifungal Activity of New Bio-Active 3,4-Dihydropyrimidin-2(1H)‑ones/thiones Under Microwave Irradiation

ACS omega, 2022-07, Vol.7 (26), p.22839-22849

2022

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Design, Antimicrobial Testing, and Molecular Docking Studies of New Chalcone and Pyrimidine Derivatives based on 2-phenyl-1H-pyrazol-3(2H)-one

Letters in drug design & discovery, 2024-08, Vol.21 (10), p.1864-1873

2024

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Synthesis and anticancer activity of some new pyrazolo[3,4-d]pyrimidin-4-one derivatives

Molecules (Basel, Switzerland), 2014-03, Vol.19 (3), p.3297-3309

2014

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Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment

Medicinal chemistry research, 2021, Vol.30 (1), p.31-49

2021

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Synthesis of Chalcones Derivatives and Their Biological Activities: A Review

ACS omega, 2022-08, Vol.7 (32), p.27769-27786

2022

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(3,5-Dimethylpyrazol-1-yl)-[4-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenyl]methanone

MolBank, 2016-12, Vol.2016 (4), p.M915

2016

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Novel pyrimidine-pyridine hybrids: Synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability

Bioorganic chemistry, 2018-04, Vol.77, p.339-348

2018

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New advances in synthesis and clinical aspects of pyrazolo[3,4-d]pyrimidine scaffolds

Bioorganic chemistry, 2018-08, Vol.78, p.341-357

2018

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Preparation of some novel thiazolidinones, imidazolinones, and azetidinone bearing pyridine and pyrimidine moieties with antimicrobial activity

Journal of heterocyclic chemistry, 2020-07, Vol.57 (7), p.2977-2989

2020

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Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold

Bioorganic chemistry, 2019-07, Vol.88, p.102964, Article 102964

2019

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New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition

Bioorganic chemistry, 2019-11, Vol.92, p.103218-103218, Article 103218

2019

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Construction and Docking Studies of Novel Pyrimido[4,5‐b]quinolines as Antimicrobial Agents

Chemistry & biodiversity, 2024-06, Vol.21 (6), p.e202400200-n/a

2024

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Review of the recent advances of pyrazole derivatives as selective COX-2 inhibitors for treating inflammation

Molecular diversity, 2024-07

2024

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Antioxidant and Antimicrobial Potential of 1,8‐Naphthyridine Based Scaffolds: Design, Synthesis and in Silico Simulation Studies within Topoisomerase II

Chemistry & biodiversity, 2024-06, Vol.21 (6), p.e202301746-n/a

2024

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Design, Synthesis, Molecular Docking of Novel Substituted Pyrimidinone Derivatives as Anticancer Agents

Polycyclic aromatic compounds, 2022-05, Vol.42 (5), p.2538-2554

2022

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A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives

Archiv der Pharmazie (Weinheim), 2024-08, Vol.357 (8), p.e2400057-n/a

2024

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Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors

Bioorganic chemistry, 2016-06, Vol.66, p.88-96

2016

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Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents

Facile One-Pot Multicomponent Synthesis of Pyrazolo-Thiazole Substituted Pyridines with Potential Anti-Proliferative Activity: Synthesis, In Vitro and In Silico Studies

New 1,2,3-Triazole-Containing Hybrids as Antitumor Candidates: Design, Click Reaction Synthesis, DFT Calculations, and Molecular Docking Study

Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives

Design, Synthesis, Docking Study of Pyrazolohydrazinopyrimidin‐4‐one Derivatives and Their Application as Antimicrobials

Antioxidant, Antimicrobial, and Molecular Docking Studies of Novel Chalcones and Schiff Bases Bearing 1, 4-naphthoquinone Moiety

Nitric Oxide-NASIDS Donor Prodrugs as Hybrid Safe Anti-inflammatory Agents

Novel 1,2-Thiazine-Pyridine Hybrid: Design, Synthesis, Antioxidant Activity and Molecular Docking Study

Efficient and Recoverable Bio-Organic Catalyst Cysteine for Synthesis, Docking Study, and Antifungal Activity of New Bio-Active 3,4-Dihydropyrimidin-2(1H)‑ones/thiones Under Microwave Irradiation

Design, Antimicrobial Testing, and Molecular Docking Studies of New Chalcone and Pyrimidine Derivatives based on 2-phenyl-1H-pyrazol-3(2H)-one

Synthesis and anticancer activity of some new pyrazolo[3,4-d]pyrimidin-4-one derivatives

Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment

Synthesis of Chalcones Derivatives and Their Biological Activities: A Review

(3,5-Dimethylpyrazol-1-yl)-[4-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenyl]methanone

Novel pyrimidine-pyridine hybrids: Synthesis, cyclooxygenase inhibition, anti-inflammatory activity and ulcerogenic liability

New advances in synthesis and clinical aspects of pyrazolo[3,4-d]pyrimidine scaffolds

Preparation of some novel thiazolidinones, imidazolinones, and azetidinone bearing pyridine and pyrimidine moieties with antimicrobial activity

Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold

New pyrimidine-benzoxazole/benzimidazole hybrids: Synthesis, antioxidant, cytotoxic activity, in vitro cyclooxygenase and phospholipase A2-V inhibition

Construction and Docking Studies of Novel Pyrimido[4,5‐b]quinolines as Antimicrobial Agents

Review of the recent advances of pyrazole derivatives as selective COX-2 inhibitors for treating inflammation

Antioxidant and Antimicrobial Potential of 1,8‐Naphthyridine Based Scaffolds: Design, Synthesis and in Silico Simulation Studies within Topoisomerase II

Design, Synthesis, Molecular Docking of Novel Substituted Pyrimidinone Derivatives as Anticancer Agents

A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives

Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors

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