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Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection

Journal of neurochemistry, 2017-11, Vol.143 (4), p.409-417

2017

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Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

Frontiers in neurology, 2020-10, Vol.11, p.590059-590059

2020

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The Evolution of Tau Phosphorylation and Interactions

Frontiers in aging neuroscience, 2019-09, Vol.11, p.256-256

2019

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Microtubule-modulating Agents in the Fight Against Neurodegeneration:Will it ever Work?

Current neuropharmacology, 2022-01, Vol.20 (4), p.782-798

2022

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Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies

Molecular and cellular neuroscience, 2017-10, Vol.84, p.132-141

2017

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Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

Drugs (New York, N.Y.), 2016-03, Vol.76 (3), p.301-313

2016

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Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction

Nature communications, 2024-02, Vol.15 (1), p.1679-1679, Article 1679

2024

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Activated MAO-B in the brain of Alzheimer patients, demonstrated by [ 11C]- l-deprenyl using whole hemisphere autoradiography

Neurochemistry international, 2011, Vol.58 (1), p.60-68

2011

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Why kiss‐and‐hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions)

Cytoskeleton (Hoboken, N.J.), 2024-01, Vol.81 (1), p.47-52

2024

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Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

Frontiers in synaptic neuroscience, 2020-02, Vol.12, p.2-2

2020

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Chronic Presence of Oligomeric Aβ Differentially Modulates Spine Parameters in the Hippocampus and Cortex of Mice With Low APP Transgene Expression

Frontiers in synaptic neuroscience, 2020-04, Vol.12, p.16-16

2020

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Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

Translational psychiatry, 2019-01, Vol.9 (1), p.7, Article 7

2019

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Triple mammalian/yeast/bacterial shuttle vectors for single and combined Lentivirus- and Sindbis virus-mediated infections of neurons

Molecular genetics and genomics : MGG, 2012-04, Vol.287 (4), p.313-324

2012

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Microtubule Dynamics in Neuronal Development, Plasticity, and Neurodegeneration

International review of cell and molecular biology, 2016, Vol.321, p.89-169

2016

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INFLAMMATORY CYTOKINE TNF‑Α AFFECTS NEURONAL DENDRITIC SPINE DENSITY IN A TAU INDEPENDENT MANNER

Acta neurobiologiae experimentalis, 2022-01, Vol.82, p.XLVI

2022

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Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes

Molecular biology of the cell, 2016-11, Vol.27 (22), p.3537-3549

2016

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Lattice light-sheet microscopy and evaluation of dendritic transport in cultured hippocampal tissue reveal high variability in mobility of the KIF1A motor domain and entry into dendritic spines

Brain research bulletin, 2023-03, Vol.194, p.13-22

2023

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Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

Molecular biology of the cell, 2014-11, Vol.25 (22), p.3541-3551

2014

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Annexins A2 and A6 interact with the extreme N terminus of tau and thereby contribute to tau's axonal localization

The Journal of biological chemistry, 2018-05, Vol.293 (21), p.8065-8076

2018

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Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport

Molecular psychiatry, 2022-07, Vol.27 (7), p.3010-3023

2022

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Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes

Brain research bulletin, 2022-11, Vol.190, p.234-243

2022

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IMPACT OF SMALL MOLECULES AND PEPTIDES ON TAU‑MICROTUBULES INTERACTION AND TAU AGGREGATION IN PRIMARY PERIPHERAL NEURONS, AND MODELS OF ALZHEIMER'S DISEASE

Acta neurobiologiae experimentalis, 2022-01, Vol.82, p.XLVI

2022

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RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

The Journal of biological chemistry, 2014-06, Vol.289 (24), p.16814-16825

2014

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DMSO modulates CNS function in a preclinical Alzheimer's disease model

Neuropharmacology, 2017-02, Vol.113 (Pt A), p.434-444

2017

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Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D

Neuropharmacology, 2016-06, Vol.105, p.84-95

2016

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Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

The Evolution of Tau Phosphorylation and Interactions

Microtubule-modulating Agents in the Fight Against Neurodegeneration:Will it ever Work?

Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies

Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction

Activated MAO-B in the brain of Alzheimer patients, demonstrated by [ 11C]- l-deprenyl using whole hemisphere autoradiography

Why kiss‐and‐hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions)

Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

Chronic Presence of Oligomeric Aβ Differentially Modulates Spine Parameters in the Hippocampus and Cortex of Mice With Low APP Transgene Expression

Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

Triple mammalian/yeast/bacterial shuttle vectors for single and combined Lentivirus- and Sindbis virus-mediated infections of neurons

Microtubule Dynamics in Neuronal Development, Plasticity, and Neurodegeneration

INFLAMMATORY CYTOKINE TNF‑Α AFFECTS NEURONAL DENDRITIC SPINE DENSITY IN A TAU INDEPENDENT MANNER

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes

Lattice light-sheet microscopy and evaluation of dendritic transport in cultured hippocampal tissue reveal high variability in mobility of the KIF1A motor domain and entry into dendritic spines

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

Annexins A2 and A6 interact with the extreme N terminus of tau and thereby contribute to tau's axonal localization

Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport

Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes

IMPACT OF SMALL MOLECULES AND PEPTIDES ON TAU‑MICROTUBULES INTERACTION AND TAU AGGREGATION IN PRIMARY PERIPHERAL NEURONS, AND MODELS OF ALZHEIMER'S DISEASE

RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

DMSO modulates CNS function in a preclinical Alzheimer's disease model

Aβ-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D

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