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TCR3d 2.0: expanding the T cell receptor structure database with new structures, tools and interactions

Nucleic acids research, 2024-09

2024

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Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

The Journal of experimental medicine, 2014-10, Vol.211 (11), p.2231-2248

2014

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LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner via its armadillo domain

Small GTPases, 2021-03, Vol.12 (2), p.133-146

2021

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Structural dissimilarity from self drives neoepitope escape from immune tolerance

Nature chemical biology, 2020-11, Vol.16 (11), p.1269-1276

2020

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Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

Nature immunology, 2016-01, Vol.17 (1), p.87-94

2016

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Structure Based Prediction of Neoantigen Immunogenicity

Frontiers in immunology, 2019-08, Vol.10 (8, 2019), p.2047

2019

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Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality

The Journal of clinical investigation, 2023-07, Vol.133 (14)

2023

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Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings

Frontiers in immunology, 2017-08, Vol.8, p.935-935

2017

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Computational design of the affinity and specificity of a therapeutic T cell receptor

PLoS computational biology, 2014-02, Vol.10 (2), p.e1003478-e1003478

2014

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Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility

Frontiers in immunology, 2019-05, Vol.10, p.966-966

2019

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Editorial: Quantification and prediction of T-cell cross-reactivity through experimental and computational methods

Frontiers in immunology, 2024, Vol.15, p.1377259-1377259

2024

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How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (9), p.E1276-E1285

2016

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Enhanced T cell receptor specificity through framework engineering

Frontiers in immunology, 2024-03, Vol.15, p.1345368-1345368

2024

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A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry

Nature communications, 2022-11, Vol.13 (1), p.7189-7189, Article 7189

2022

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Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma

Scientific reports, 2022-07, Vol.12 (1), p.12068-12068, Article 12068

2022

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Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics

The Journal of immunology (1950), 2011-03, Vol.186 (5), p.2950-2958

2011

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Advanced Genomics-Based Approaches for Defining Allograft Rejection With Single Cell Resolution

Frontiers in immunology, 2021-10, Vol.12, p.750754-750754

2021

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An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry

Structure (London), 2016-07, Vol.24 (7), p.1142-1154

2016

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Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope

Nature communications, 2021-11, Vol.12 (1), p.6423-6423, Article 6423

2021

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Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes

Frontiers in immunology, 2022-04, Vol.13, p.887759-887759

2022

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HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV

Cell reports (Cambridge), 2021-07, Vol.36 (2), p.109378, Article 109378

2021

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Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes

Biochemical journal, 2008-10, Vol.415 (2), p.183-196

2008

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Peptide Modulation of Class I Major Histocompatibility Complex Protein Molecular Flexibility and the Implications for Immune Recognition

The Journal of biological chemistry, 2013-08, Vol.288 (34), p.24372-24381

2013

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Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts

Frontiers in immunology, 2023-12, Vol.14, p.1287546-1287546

2023

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TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility

The Journal of immunology (1950), 2014-03, Vol.192 (6), p.2885-2891

2014

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TCR3d 2.0: expanding the T cell receptor structure database with new structures, tools and interactions

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner via its armadillo domain

Structural dissimilarity from self drives neoepitope escape from immune tolerance

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

Structure Based Prediction of Neoantigen Immunogenicity

Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality

Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings

Computational design of the affinity and specificity of a therapeutic T cell receptor

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility

Editorial: Quantification and prediction of T-cell cross-reactivity through experimental and computational methods

How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire

Enhanced T cell receptor specificity through framework engineering

A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry

Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma

Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics

Advanced Genomics-Based Approaches for Defining Allograft Rejection With Single Cell Resolution

An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry

Reversion analysis reveals the in vivo immunogenicity of a poorly MHC I-binding cancer neoepitope

Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes

HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes

Peptide Modulation of Class I Major Histocompatibility Complex Protein Molecular Flexibility and the Implications for Immune Recognition

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts

TCR scanning of peptide/MHC through complementary matching of receptor and ligand molecular flexibility

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