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Neutrophils as effector cells for antibody-based immunotherapy of cancer

Seminars in cancer biology, 2013-06, Vol.23 (3), p.190-199

2013

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Cross-talk between pathogen recognizing Toll-like receptors and immunoglobulin Fc receptors in immunity

Immunological reviews, 2015-11, Vol.268 (1), p.311-327

2015

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Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity

The Journal of clinical investigation, 2021-03, Vol.131 (6), p.1-16

2021

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Immunoglobulin A: A next generation of therapeutic antibodies?

mAbs, 2011-07, Vol.3 (4), p.352-361

2011

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IgA enhances NETosis and release of neutrophil extracellular traps by polymorphonuclear cells via Fcα receptor I

The Journal of immunology (1950), 2014-03, Vol.192 (5), p.2374-2383

2014

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An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy

Molecular cancer therapeutics, 2024-02, Vol.23 (2), p.187

2024

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In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8), p.3209-3217

2010

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NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models

International journal of molecular sciences, 2021-10, Vol.22 (20), p.11057

2021

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Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease

Frontiers in immunology, 2022-03, Vol.13, p.732977-732977

2022

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Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer

Current topics in microbiology and immunology, 2014, Vol.382, p.373

2014

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FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling

Frontiers in immunology, 2019-01, Vol.9, p.3191-3191

2019

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Blocking Fcα receptor I on granulocytes prevents tissue damage induced by IgA autoantibodies

The Journal of immunology (1950), 2012-08, Vol.189 (4), p.1594-1601

2012

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Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1856-1866

2015

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Peptide mimetics of immunoglobulin A (IgA) and FcαRI block IgA‐induced human neutrophil activation and migration

European journal of immunology, 2017-10, Vol.47 (10), p.1835-1845

2017

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Targeting FcαRI on polymorphonuclear cells induces tumor cell killing through autophagy

The Journal of immunology (1950), 2011-07, Vol.187 (2), p.726-732

2011

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Immunoglobulin A: FcαRI Interactions Induce Neutrophil Migration Through Release of Leukotriene B4

Gastroenterology (New York, N.Y. 1943), 2009-12, Vol.137 (6), p.2018-2029.e3

2009

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1008 Validation of expression of therapeutic targets in T cells and Macrophages by mass spectrometry based proteomics

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1116-A1116

2023

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Enhanced FcαRI‐mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

European journal of immunology, 2012-07, Vol.42 (7), p.1815-1821

2012

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Inside-out regulation of Fc alpha RI (CD89) depends on PP2A

The Journal of immunology (1950), 2008-09, Vol.181 (6), p.4080-4088

2008

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c-Jun activating binding protein 1 binds to the IgA receptor and modulates protein levels of FcαRI and FcRγ-chain

European journal of immunology, 2010-07, Vol.40 (7), p.2035-2040

2010

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Signaling through mutants of the IgA receptor CD89 and consequences for Fc receptor gamma-chain interaction

Journal of Immunology, 2006-03, Vol.176 (6), p.3603-3610

2006

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Protein 4.1G binds to a unique motif within the FcγRI cytoplasmic tail

Molecular immunology, 2008-04, Vol.45 (7), p.2069-2075

2008

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Direct Interaction between FcγRI (CD64) and Periplakin Controls Receptor Endocytosis and Ligand Binding Capacity

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (28), p.10392-10397

2004

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Enhanced F cα RI ‐mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

European journal of immunology, 2012-07, Vol.42 (7), p.1815-1821

2012

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Enhanced Fc[alpha]RI-mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

European journal of immunology, 2012-07, Vol.42 (7), p.1815-1821

2012

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Neutrophils as effector cells for antibody-based immunotherapy of cancer

Cross-talk between pathogen recognizing Toll-like receptors and immunoglobulin Fc receptors in immunity

Augmented antibody-based anticancer therapeutics boost neutrophil cytotoxicity

Immunoglobulin A: A next generation of therapeutic antibodies?

IgA enhances NETosis and release of neutrophil extracellular traps by polymorphonuclear cells via Fcα receptor I

An Antibody-Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy

In vivo cytotoxicity of type I CD20 antibodies critically depends on Fc receptor ITAM signaling

NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models

Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease

Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling

Blocking Fcα receptor I on granulocytes prevents tissue damage induced by IgA autoantibodies

Antibody-opsonized bacteria evoke an inflammatory dendritic cell phenotype and polyfunctional Th cells by cross-talk between TLRs and FcRs

Peptide mimetics of immunoglobulin A (IgA) and FcαRI block IgA‐induced human neutrophil activation and migration

Targeting FcαRI on polymorphonuclear cells induces tumor cell killing through autophagy

Immunoglobulin A: FcαRI Interactions Induce Neutrophil Migration Through Release of Leukotriene B4

1008 Validation of expression of therapeutic targets in T cells and Macrophages by mass spectrometry based proteomics

Enhanced FcαRI‐mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

Inside-out regulation of Fc alpha RI (CD89) depends on PP2A

c-Jun activating binding protein 1 binds to the IgA receptor and modulates protein levels of FcαRI and FcRγ-chain

Signaling through mutants of the IgA receptor CD89 and consequences for Fc receptor gamma-chain interaction

Protein 4.1G binds to a unique motif within the FcγRI cytoplasmic tail

Direct Interaction between FcγRI (CD64) and Periplakin Controls Receptor Endocytosis and Ligand Binding Capacity

Enhanced F cα RI ‐mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

Enhanced Fc[alpha]RI-mediated neutrophil migration towards tumour colonies in the presence of endothelial cells

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