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Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction

Mini reviews in medicinal chemistry, 2007-05, Vol.7 (5), p.461-466

2007

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Chemical aspects of pharmacological prophylaxis against nerve agent poisoning

Current medicinal chemistry, 2009-08, Vol.16 (23), p.2977-2986

2009

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Organophosphates⧸Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, And Treatment

Advances in Clinical Chemistry, 2004, Vol.38, p.151-216

Bajgar, Jirí

2004

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Pharmacokinetics and pharmacodynamics of some oximes and associated therapeutic consequences: a critical review

Journal of applied toxicology, 2010-11, Vol.30 (8), p.719-729

2010

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Nerve Agents Poisoning and Its Treatment in Schematic Figures and Tables

Bajgar, Jiri

1, 2012

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Inhibition of cholinesterases following percutaneous intoxication with V agents in rats

Toxin reviews, 2021-07, Vol.40 (3), p.251-256

2021

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An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice

Clinical toxicology (Philadelphia, Pa.), 2009-01, Vol.47 (1), p.72-76

2009

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Laboratory examination in nerve agent intoxication

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2013, Vol.56 (3), p.89-96

Bajgar, Jirí

2013

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Inhibition of Acetylcholinesterase in Different Structures of the Rat Brain Following Soman Intoxication Pretreated with Huperzine A

International journal of molecular sciences, 2007-11, Vol.8 (11), p.1165-1176

2007

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Complex view on poisoning with nerve agents and organophosphates

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2005, Vol.48 (1), p.3-21

Bajgar, Jirí

2005

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Cholinesterase Reactivators as Prophylactics Against Nerve Agents

Current bioactive compounds, 2010-03, Vol.6 (1), p.2-8

2010

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Evaluation of the Neuroprotective Efficacy of Newly Developed Oximes (K206, K269) and Currently Available Oximes (Obidoxime, HI‐6) in Cyclosarin‐Poisoned Rats

Basic & clinical pharmacology & toxicology, 2009-03, Vol.104 (3), p.228-235

2009

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Pretreatment with Huperzine A Protects Acetylcholinesterase in the Rat Brain Against Inhibition by VX and Russian VX

Letters in drug design & discovery, 2009-12, Vol.6 (8), p.563-567

2009

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Structure-Activity Relationship of Acetylcholinesterase Reactivators -Antidotes Against Nerve Agents

Letters in organic chemistry, 2007-04, Vol.4 (3), p.212-217

2007

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Optimal Choice of Acetylcholinesterase Reactivators for Antidoral Treatment of Nerve Agent Intoxication

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2010, Vol.53 (4), p.207-211

Bajgar, Jiří

2010

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Natural Detoxification Capacity to Inactivate Nerve Agents Sarin and VX in the Rat Blood

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2015, Vol.58 (4), p.128-130

2015

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Evaluation of flow injection analysis for determination of cholinesterase activities in biological material

Chemico-biological interactions, 2010-09, Vol.187 (1), p.225-228

2010

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Currently Used Cholinesterase Reactivators Against Nerve Agent Intoxication: Comparison of Their Effectivity in Vitro

Drug and chemical toxicology (New York, N.Y. 1978), 2007-01, Vol.30 (1), p.31-40

2007

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A Comparison of the Efficacy of Newly Developed Reversible Inhibitors of Acetylcholinesterase with Commonly Used Pyridostigmine as Pharmacological Pre-Treatment of Soman-Poisoned Mice

Basic & clinical pharmacology & toxicology, 2012-04, Vol.110 (4), p.322-326

2012

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A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

Chemico-biological interactions, 2008-09, Vol.175 (1), p.425-427

2008

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Protective effect of reversible cholinesterase inhibitors (tacrine, pyridostigmine) and eqbuche against VX poisoning and brain acetylcholinesterase inhibition in rats

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2008, Vol.51 (4), p.223-228

Bajgar, Jirí

2008

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The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2012, Vol.55 (1), p.27-31

2012

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Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain

Journal of pharmaceutical and biomedical analysis, 2011-04, Vol.54 (5), p.1082-1087

2011

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Effective bisquaternary reactivators of tabun-inhibited AChE

Journal of applied toxicology, 2005-11, Vol.25 (6), p.491-495

2005

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A comparison of the reactivating and therapeutic efficacy of the newly developed bispyridinium oxime K203 with currently available oximes, in sarin poisoned rats and mice

Journal of applied biomedicine, 2011-01, Vol.9 (4), p.225-230

2011

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Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction

Chemical aspects of pharmacological prophylaxis against nerve agent poisoning

Organophosphates⧸Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, And Treatment

Pharmacokinetics and pharmacodynamics of some oximes and associated therapeutic consequences: a critical review

Nerve Agents Poisoning and Its Treatment in Schematic Figures and Tables

Inhibition of cholinesterases following percutaneous intoxication with V agents in rats

An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice

Laboratory examination in nerve agent intoxication

Inhibition of Acetylcholinesterase in Different Structures of the Rat Brain Following Soman Intoxication Pretreated with Huperzine A

Complex view on poisoning with nerve agents and organophosphates

Cholinesterase Reactivators as Prophylactics Against Nerve Agents

Evaluation of the Neuroprotective Efficacy of Newly Developed Oximes (K206, K269) and Currently Available Oximes (Obidoxime, HI‐6) in Cyclosarin‐Poisoned Rats

Pretreatment with Huperzine A Protects Acetylcholinesterase in the Rat Brain Against Inhibition by VX and Russian VX

Structure-Activity Relationship of Acetylcholinesterase Reactivators -Antidotes Against Nerve Agents

Optimal Choice of Acetylcholinesterase Reactivators for Antidoral Treatment of Nerve Agent Intoxication

Natural Detoxification Capacity to Inactivate Nerve Agents Sarin and VX in the Rat Blood

Evaluation of flow injection analysis for determination of cholinesterase activities in biological material

Currently Used Cholinesterase Reactivators Against Nerve Agent Intoxication: Comparison of Their Effectivity in Vitro

A Comparison of the Efficacy of Newly Developed Reversible Inhibitors of Acetylcholinesterase with Commonly Used Pyridostigmine as Pharmacological Pre-Treatment of Soman-Poisoned Mice

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats

Protective effect of reversible cholinesterase inhibitors (tacrine, pyridostigmine) and eqbuche against VX poisoning and brain acetylcholinesterase inhibition in rats

The ability of oxime mixtures to increase the reactivating and therapeutic efficacy of antidotal treatment of cyclosarin poisoning in rats and mice

Partition of bispyridinium oximes (trimedoxime and K074) administered in therapeutic doses into different parts of the rat brain

Effective bisquaternary reactivators of tabun-inhibited AChE

A comparison of the reactivating and therapeutic efficacy of the newly developed bispyridinium oxime K203 with currently available oximes, in sarin poisoned rats and mice

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