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Structural biology of factor VIIa/tissue factor initiated coagulation

Frontiers in bioscience, 2012-06, Vol.17 (7), p.2476-2494

2012

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Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis

The Journal of biological chemistry, 2014-11, Vol.289 (45), p.31647-31661

2014

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The mechanism underlying activation of factor IX by factor XIa

Thrombosis research, 2014-05, Vol.133 (1), p.S48-S51

2014

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Structure and biology of tissue factor pathway inhibitor

Thrombosis and haemostasis, 2001-10, Vol.86 (4), p.959-972

2001

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Plasmin‐mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

Journal of thrombosis and haemostasis, 2020-05, Vol.18 (5), p.1171-1182

2020

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Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1

Journal of clinical medicine, 2020-11, Vol.9 (11), p.3684

2020

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Structure of human factor VIIa–soluble tissue factor with calcium, magnesium and rubidium

Acta crystallographica. Section D, Biological crystallography., 2021-06, Vol.77 (6), p.809-819

2021

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Sodium‐site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study

Journal of thrombosis and haemostasis, 2019-04, Vol.17 (4), p.574-584

2019

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The N-terminal Epidermal Growth Factor-like Domain in Factor IX and Factor X Represents an Important Recognition Motif for Binding to Tissue Factor

The Journal of biological chemistry, 2002-02, Vol.277 (5), p.3622-3631

2002

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Structure-Function Analysis of the Reactive Site in the First Kunitz-type Domain of Human Tissue Factor Pathway Inhibitor-2

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17500-17507

2004

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Na + Site in Blood Coagulation Factor IXa: Effect on Catalysis and Factor VIIIa Binding

Journal of molecular biology, 2005-07, Vol.350 (1), p.78-91

2005

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Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Journal of molecular biology, 2013-06, Vol.425 (11), p.1961-1981

2013

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Engineering Kunitz Domain 1 (KD1) of Human Tissue Factor Pathway Inhibitor-2 to Selectively Inhibit Fibrinolysis: PROPERTIES OF KD1-L17R VARIANT

The Journal of biological chemistry, 2011-02, Vol.286 (6), p.4329-4340

2011

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High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: UNPREDICTED CONFORMATION OF THE 192-193 PEPTIDE BOND AND MAPPING OF Ca²⁺, Mg²⁺, Na⁺, AND Zn²⁺ SITES IN FACTOR VIIa

The Journal of biological chemistry, 2006-08, Vol.281 (34), p.24873-24888

2006

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A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.38200-38209

2012

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Decoy Plasminogen Receptor Containing a Selective Kunitz-Inhibitory Domain

Biochemistry (Easton), 2014-01, Vol.53 (3), p.505-517

2014

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Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography

Analytical biochemistry, 2015-06, Vol.479, p.6-14

2015

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Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair

Annals of the rheumatic diseases, 2018-05, Vol.77 (5), p.760-769

2018

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Tissue factor pathway inhibitor: potential therapeutic applications

Thrombosis and haemostasis, 1997-07, Vol.78 (1), p.471-477

1997

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Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

Science translational medicine, 2023-03, Vol.15 (688), p.eabq2395

2023

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The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts

Bone Research, 2014-07, Vol.2 (1), p.14011, Article 14011

2014

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High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor

The Journal of biological chemistry, 2006-08, Vol.281 (34), p.24873-24888

2006

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Structure–Function Relationships in Factor IX and Factor IXa

Trends in Cardiovascular Medicine, 2003, Vol.13 (1), p.39-45

2003

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Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition

The Journal of biological chemistry, 2005-07, Vol.280 (30), p.27832-27838

2005

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Substitution of the Gla Domain in Factor X with That of Protein C Impairs Its Interaction with Factor VIIa/Tissue Factor

The Journal of biological chemistry, 2007-05, Vol.282 (21), p.15632-15644

2007

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Structural biology of factor VIIa/tissue factor initiated coagulation

Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis

The mechanism underlying activation of factor IX by factor XIa

Structure and biology of tissue factor pathway inhibitor

Plasmin‐mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1

Structure of human factor VIIa–soluble tissue factor with calcium, magnesium and rubidium

Sodium‐site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study

The N-terminal Epidermal Growth Factor-like Domain in Factor IX and Factor X Represents an Important Recognition Motif for Binding to Tissue Factor

Structure-Function Analysis of the Reactive Site in the First Kunitz-type Domain of Human Tissue Factor Pathway Inhibitor-2

Na + Site in Blood Coagulation Factor IXa: Effect on Catalysis and Factor VIIIa Binding

Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Engineering Kunitz Domain 1 (KD1) of Human Tissue Factor Pathway Inhibitor-2 to Selectively Inhibit Fibrinolysis: PROPERTIES OF KD1-L17R VARIANT

High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor: UNPREDICTED CONFORMATION OF THE 192-193 PEPTIDE BOND AND MAPPING OF Ca²⁺, Mg²⁺, Na⁺, AND Zn²⁺ SITES IN FACTOR VIIa

A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa

Decoy Plasminogen Receptor Containing a Selective Kunitz-Inhibitory Domain

Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography

Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair

Tissue factor pathway inhibitor: potential therapeutic applications

Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts

High Resolution Structures of p-Aminobenzamidine- and Benzamidine-VIIa/Soluble Tissue Factor

Structure–Function Relationships in Factor IX and Factor IXa

Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition

Substitution of the Gla Domain in Factor X with That of Protein C Impairs Its Interaction with Factor VIIa/Tissue Factor

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