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Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action

Environmental and molecular mutagenesis, 2005, Vol.45 (2-3), p.106-114

2005

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Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Toxicology and applied pharmacology, 2012-11, Vol.264 (3), p.377-386

2012

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Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: The role of polycyclic aromatic hydrocarbons

Mutation research, 2011-09, Vol.714 (1), p.53-62

2011

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Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse

Toxicology and applied pharmacology, 2015-09, Vol.287 (2), p.149-160

2015

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Urban Dust Particulate Matter Alters PAH-Induced Carcinogenesis by Inhibition of CYP1A1 and CYP1B1

Toxicological sciences, 2007-01, Vol.95 (1), p.63-73

2007

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Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites

Carcinogenesis (New York), 1999-10, Vol.20 (10), p.1885-1891

1999

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Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH–DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis

Carcinogenesis (New York), 2001-07, Vol.22 (7), p.1077-1086

2001

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Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[a,l]pyrene-Induced Tumor Formation

Chemical research in toxicology, 2002-09, Vol.15 (9), p.1127-1135

2002

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Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction

Food and chemical toxicology, 2018-05, Vol.115, p.136-147

2018

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Synthetic, Crystallographic, Computational, and Biological Studies of 1,4-Difluorobenzo[c]phenanthrene and Its Metabolites

Journal of organic chemistry, 2007-09, Vol.72 (20), p.7625-7633

2007

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Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry

Chemical research in toxicology, 2016-10, Vol.29 (10), p.1641-1650

2016

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Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential

Toxicological sciences, 2015-07, Vol.146 (1), p.135-145

2015

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Diesel exhaust influences carcinogenic PAH-induced genotoxicity and gene expression in human breast epithelial cells in culture

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007-12, Vol.625 (1), p.72-82

2007

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Transplacental carcinogenesis with dibenzo[ def , p ]chrysene (DBC): Timing of maternal exposures determines target tissue response in offspring

Cancer letters, 2012-04, Vol.317 (1), p.49-55

2012

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Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice

Toxicological sciences, 2013-09, Vol.135 (1), p.48-62

2013

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Proteomic analysis of MCF-7 cells treated with benzo[ a ]pyrene, dibenzo[ a , l ]pyrene, coal tar extract, and diesel exhaust extract

Toxicology (Amsterdam), 2008-07, Vol.249 (1), p.1-10

2008

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Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[ a]pyrene DNA adduct formation in human cells

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1283-1287

2005

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Developing a smartphone software package for predicting atmospheric pollutant concentrations at mobile locations

Computer journal, 2015-06, Vol.58 (6), p.1431-1442

2015

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Dibenzo[def,p]chrysene transplacental carcinogenesis in wild‐type, Cyp1b1 knockout, and CYP1B1 humanized mice

Molecular carcinogenesis, 2017-01, Vol.56 (1), p.163-171

2017

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Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[c]phenanthrene and Its Metabolites: Synthesis, Physical, and Biological Properties

Journal of the American Chemical Society, 2000-12, Vol.122 (51), p.12629-12636

2000

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The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo

Cancer letters, 2008-06, Vol.265 (1), p.135-147

2008

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Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a

Cancer research (Chicago, Ill.), 2005-02, Vol.65 (4), p.1251-1258

2005

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Isolation of Potential Cancer Chemopreventive Agents from Eriodictyon californicum

Journal of natural products (Washington, D.C.), 1992-03, Vol.55 (3), p.357-363

1992

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Competitive inhibition of carcinogen‐activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar

International journal of cancer, 2007-03, Vol.120 (6), p.1161-1168

2007

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Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin

Toxicology and applied pharmacology, 2013-03, Vol.267 (2), p.192-199

2013

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Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action

Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: The role of polycyclic aromatic hydrocarbons

Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse

Urban Dust Particulate Matter Alters PAH-Induced Carcinogenesis by Inhibition of CYP1A1 and CYP1B1

Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites

Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH–DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis

Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[a,l]pyrene-Induced Tumor Formation

Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction

Synthetic, Crystallographic, Computational, and Biological Studies of 1,4-Difluorobenzo[c]phenanthrene and Its Metabolites

Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry

Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential

Diesel exhaust influences carcinogenic PAH-induced genotoxicity and gene expression in human breast epithelial cells in culture

Transplacental carcinogenesis with dibenzo[ def , p ]chrysene (DBC): Timing of maternal exposures determines target tissue response in offspring

Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice

Proteomic analysis of MCF-7 cells treated with benzo[ a ]pyrene, dibenzo[ a , l ]pyrene, coal tar extract, and diesel exhaust extract

Effects of suberoylanilide hydroxamic acid and trichostatin A on induction of cytochrome P450 enzymes and benzo[ a]pyrene DNA adduct formation in human cells

Developing a smartphone software package for predicting atmospheric pollutant concentrations at mobile locations

Dibenzo[def,p]chrysene transplacental carcinogenesis in wild‐type, Cyp1b1 knockout, and CYP1B1 humanized mice

Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[c]phenanthrene and Its Metabolites: Synthesis, Physical, and Biological Properties

The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo

Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a

Isolation of Potential Cancer Chemopreventive Agents from Eriodictyon californicum

Competitive inhibition of carcinogen‐activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar

Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin

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