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5-Hydroxymethylfurfural Alleviates Inflammatory Lung Injury by Inhibiting Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation

Frontiers in cell and developmental biology, 2021-12, Vol.9, p.782427-782427

2021

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Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis

European journal of medicinal chemistry, 2020-01, Vol.185, p.111823-111823, Article 111823

2020

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Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives

European journal of medicinal chemistry, 2018-04, Vol.150, p.195-205

2018

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Anti-Tumor Drug Discovery Based on Natural Product β-Elemene: Anti-Tumor Mechanisms and Structural Modification

Molecules (Basel, Switzerland), 2021-03, Vol.26 (6), p.1499

2021

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Antidepressant Drug Discovery and Development: Mechanism and Drug Design Based on Small Molecules

Advanced therapeutics, 2022-05, Vol.5 (5), p.n/a

2022

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Artificial Intelligence-Assisted Optimization of Antipigmentation Tyrosinase Inhibitors: De Novo Molecular Generation Based on a Low Activity Lead Compound

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7260-7275

2024

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Bisamide CXCR4 Modulators: Novel Anti‐IBD Agents Acting on the Chemotaxis of Inflammatory Cells

Advanced therapeutics, 2022-06, Vol.5 (6), p.n/a

2022

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Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.1080-1099

2020

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Chiral separation, configurational identification and antihypertensive evaluation of (±)-7,8-dihydroxy-3-methyl-isochromanone-4

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (20), p.6490-6493

2012

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Click chemistry-aided drug discovery: A retrospective and prospective outlook

European journal of medicinal chemistry, 2024-01, Vol.264, p.116037-116037, Article 116037

2024

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Combination of chemotherapy and gaseous signaling molecular therapy: Novel β‐elemene nitric oxide donor derivatives against leukemia

Drug development research, 2023-06, Vol.84 (4), p.718-735

2023

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Coordinating Activation Strategy‐Induced Selective C−H Trifluoromethylation of Anilines

ChemCatChem, 2018-03, Vol.10 (5), p.965-970

2018

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Cu-catalyzed coupling of unactivated tertiary alkyl alcohols with thiols via C–O bond cleavage

Tetrahedron letters, 2022-01, Vol.89, p.153604, Article 153604

2022

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CXCR4/CXCL12 axis: “old” pathway as “novel” target for anti‐inflammatory drug discovery

Medicinal research reviews, 2024-05, Vol.44 (3), p.1189-1220

2024

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Deep learning for advancing peptide drug development: Tools and methods in structure prediction and design

European journal of medicinal chemistry, 2024-03, Vol.268, p.116262-116262, Article 116262

2024

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Design, synthesis and antioxidant activity evaluation of novel β-elemene derivatives

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3407-3411

2014

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Design, synthesis and antitumor efficacy evaluation of a series of novel β-elemene-based macrocycles

Bioorganic & medicinal chemistry, 2022-11, Vol.74, p.117049-117049, Article 117049

2022

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Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates

Bioorganic & medicinal chemistry, 2013-12, Vol.21 (24), p.7742-7751

2013

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Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease

European journal of medicinal chemistry, 2019-10, Vol.180, p.367-382

2019

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Design, synthesis and biological evaluation of novel histone deacetylase (HDAC) inhibitors derived from β-elemene scaffold

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2195991-2195991

2023

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Design, synthesis and biological evaluation of potential anti-AD hybrids with monoamine oxidase B inhibitory and iron-chelating effects

Bioorganic chemistry, 2021-03, Vol.108, p.104564-104564, Article 104564

2021

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Development of CXCR4 modulators based on the lead compound RB-108

European journal of medicinal chemistry, 2019-07, Vol.173, p.32-43

2019

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Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library

European journal of medicinal chemistry, 2017-01, Vol.126, p.464-475

2017

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Differential and Nonredundant Roles of Phospholipase C{gamma}2 and Phospholipase C{gamma}1 in the Terminal Maturation of NK Cells

The Journal of immunology (1950), 2006-10, Vol.177 (8), p.5365

2006

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Differential and Nonredundant Roles of Phospholipase C gamma 2 and Phospholipase C gamma 1 in the Terminal Maturation of NK Cells

Journal of Immunology, 2006-10, Vol.177 (8), p.5365-5376

2006

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5-Hydroxymethylfurfural Alleviates Inflammatory Lung Injury by Inhibiting Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation

Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis

Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives

Anti-Tumor Drug Discovery Based on Natural Product β-Elemene: Anti-Tumor Mechanisms and Structural Modification

Antidepressant Drug Discovery and Development: Mechanism and Drug Design Based on Small Molecules

Artificial Intelligence-Assisted Optimization of Antipigmentation Tyrosinase Inhibitors: De Novo Molecular Generation Based on a Low Activity Lead Compound

Bisamide CXCR4 Modulators: Novel Anti‐IBD Agents Acting on the Chemotaxis of Inflammatory Cells

Chemical approaches for the enhancement of porphyrin skeleton-based photodynamic therapy

Chiral separation, configurational identification and antihypertensive evaluation of (±)-7,8-dihydroxy-3-methyl-isochromanone-4

Click chemistry-aided drug discovery: A retrospective and prospective outlook

Combination of chemotherapy and gaseous signaling molecular therapy: Novel β‐elemene nitric oxide donor derivatives against leukemia

Coordinating Activation Strategy‐Induced Selective C−H Trifluoromethylation of Anilines

Cu-catalyzed coupling of unactivated tertiary alkyl alcohols with thiols via C–O bond cleavage

CXCR4/CXCL12 axis: “old” pathway as “novel” target for anti‐inflammatory drug discovery

Deep learning for advancing peptide drug development: Tools and methods in structure prediction and design

Design, synthesis and antioxidant activity evaluation of novel β-elemene derivatives

Design, synthesis and antitumor efficacy evaluation of a series of novel β-elemene-based macrocycles

Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates

Design, synthesis and biological evaluation of hydroxypyridinone-coumarin hybrids as multimodal monoamine oxidase B inhibitors and iron chelates against Alzheimer's disease

Design, synthesis and biological evaluation of novel histone deacetylase (HDAC) inhibitors derived from β-elemene scaffold

Design, synthesis and biological evaluation of potential anti-AD hybrids with monoamine oxidase B inhibitory and iron-chelating effects

Development of CXCR4 modulators based on the lead compound RB-108

Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library

Differential and Nonredundant Roles of Phospholipase C{gamma}2 and Phospholipase C{gamma}1 in the Terminal Maturation of NK Cells

Differential and Nonredundant Roles of Phospholipase C gamma 2 and Phospholipase C gamma 1 in the Terminal Maturation of NK Cells

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