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Therapeutic Approaches to Alzheimer’s Disease Through Modulation of NRF2

Neuromolecular medicine, 2019-03, Vol.21 (1), p.1-11

2019

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NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (25), p.12516-12523

2019

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Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain

Annals of neurology, 2015-03, Vol.77 (3), p.504-516

2015

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Drug–Target Interaction Deep Learning-Based Model Identifies the Flavonoid Troxerutin as a Candidate TRPV1 Antagonist

Applied sciences, 2023-05, Vol.13 (9), p.5617

2023

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Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice

Biomolecules & therapeutics, 2019-01, Vol.27 (1), p.107-116

2019

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Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

The Journal of neuroscience, 2017-05, Vol.37 (20), p.5099-5110

2017

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Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy

Journal of controlled release, 2015-10, Vol.216, p.140-148

2015

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Atf3 induction is a therapeutic target for obesity and metabolic diseases

Biochemical and biophysical research communications, 2018-10, Vol.504 (4), p.903-908

2018

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Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation

Scientific reports, 2016-01, Vol.6 (1), p.19377-19377, Article 19377

2016

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Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis

Theranostics, 2018-01, Vol.8 (17), p.4795-4804

2018

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P3‐041: Drug Repositioning of XHC for Alzheimer’s Disease: Bace1 Promoter Repressing Activity of XHC

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_17), p.P833-P833

2016

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ROLE OF ADIPONECTIN IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1042-P1042

2016

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P3‐037: A Novel Compound from Antartic Lichen Restores Cognition VIA Suppression of Inflammasome and Bace1 Expression in Alzheimer’s Disease Mice

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_17), p.P831-P831

2016

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PRO-APOPTOTIC FUNCTION OF PIN1-MEDIATED NOTCH1 ACTIVATION IN ISCHEMIC NEURONAL DEATH

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P464-P464

2016

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THE INTERACTION BETWEEN NOTCH-1 AND HIF-1A PROMOTES ISCHEMIC NEURONAL DEATH

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P661-P661

2016

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A NOVEL COMPOUND FROM ANTARTIC LICHEN RESTORES COGNITION VIA SUPPRESSION OF INFLAMMASOME AND BACE1 EXPRESSION IN ALZHEIMER’S DISEASE MICE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P831-P831

2016

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P2‐130: The Interaction between Notch‐1 and Hif‐1A Promotes Ischemic Neuronal Death

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_13), p.P661-P661

2016

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DRUG REPOSITIONING OF XHC FOR ALZHEIMER’S DISEASE: BACE1 PROMOTER REPRESSING ACTIVITY OF XHC

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P833-P833

2016

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P3‐044: Mild Beta‐Amyloid Preconditioning has a Neuroprotective Effect by Enhancing Cellular Tolerance VIA BDNF Pathway

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_17), p.P833-P834

2016

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P4‐075: Role of Adiponectin in the Pathogenesis of Alzheimer’s Disease

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_21), p.P1042-P1042

2016

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INHIBITION OF MITOCHONDRIAL FISSION AMELIORATES THE PATHOGENESIS OF ALZHEIMER'S DISEASE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1024-P1024

2016

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P1‐161: Pro‐Apoptotic Function of Pin1‐Mediated Notch1 Activation in Ischemic Neuronal Death

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_9), p.P464-P464

2016

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THE DRUG TG REDUCING BACE1 EXPRESSION LEVEL AND PREVENTING COGNITIVE IMPAIRMENT IN ALZHEIMER'S DISEASE MICE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P434-P435

2016

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P4‐024: Inhibition of Mitochondrial Fission Ameliorates the Pathogenesis of Alzheimer's Disease

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_21), p.P1024-P1024

2016

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MILD BETA-AMYLOID PRECONDITIONING HAS A NEUROPROTECTIVE EFFECT BY ENHANCING CELLULAR TOLERANCE VIA BDNF PATHWAY

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P833-P834

2016

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Therapeutic Approaches to Alzheimer’s Disease Through Modulation of NRF2

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain

Drug–Target Interaction Deep Learning-Based Model Identifies the Flavonoid Troxerutin as a Candidate TRPV1 Antagonist

Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice

Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy

Atf3 induction is a therapeutic target for obesity and metabolic diseases

Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation

Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis

P3‐041: Drug Repositioning of XHC for Alzheimer’s Disease: Bace1 Promoter Repressing Activity of XHC

ROLE OF ADIPONECTIN IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE

P3‐037: A Novel Compound from Antartic Lichen Restores Cognition VIA Suppression of Inflammasome and Bace1 Expression in Alzheimer’s Disease Mice

PRO-APOPTOTIC FUNCTION OF PIN1-MEDIATED NOTCH1 ACTIVATION IN ISCHEMIC NEURONAL DEATH

THE INTERACTION BETWEEN NOTCH-1 AND HIF-1A PROMOTES ISCHEMIC NEURONAL DEATH

A NOVEL COMPOUND FROM ANTARTIC LICHEN RESTORES COGNITION VIA SUPPRESSION OF INFLAMMASOME AND BACE1 EXPRESSION IN ALZHEIMER’S DISEASE MICE

P2‐130: The Interaction between Notch‐1 and Hif‐1A Promotes Ischemic Neuronal Death

DRUG REPOSITIONING OF XHC FOR ALZHEIMER’S DISEASE: BACE1 PROMOTER REPRESSING ACTIVITY OF XHC

P3‐044: Mild Beta‐Amyloid Preconditioning has a Neuroprotective Effect by Enhancing Cellular Tolerance VIA BDNF Pathway

P4‐075: Role of Adiponectin in the Pathogenesis of Alzheimer’s Disease

INHIBITION OF MITOCHONDRIAL FISSION AMELIORATES THE PATHOGENESIS OF ALZHEIMER'S DISEASE

P1‐161: Pro‐Apoptotic Function of Pin1‐Mediated Notch1 Activation in Ischemic Neuronal Death

THE DRUG TG REDUCING BACE1 EXPRESSION LEVEL AND PREVENTING COGNITIVE IMPAIRMENT IN ALZHEIMER'S DISEASE MICE

P4‐024: Inhibition of Mitochondrial Fission Ameliorates the Pathogenesis of Alzheimer's Disease

MILD BETA-AMYLOID PRECONDITIONING HAS A NEUROPROTECTIVE EFFECT BY ENHANCING CELLULAR TOLERANCE VIA BDNF PATHWAY

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