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Tailoring FXR Modulators for Intestinal Specificity: Recent Progress and Insights

Molecules (Basel, Switzerland), 2024-05, Vol.29 (9), p.2022

2024

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REV-ERB agonism improves liver pathology in a mouse model of NASH

PloS one, 2020-10, Vol.15 (10), p.e0236000-e0236000

2020

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2,5-Diketopiperazines (DKPs): Promising Scaffolds for Anticancer Agents

Current pharmaceutical design, 2024-01, Vol.30 (8), p.597

2024

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Nature communications, 2022-11, Vol.13 (1), p.7131-7131, Article 7131

2022

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Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2112-2132

2022

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Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases

European journal of medicinal chemistry, 2020-08, Vol.200, p.112439, Article 112439

2020

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Design, Synthesis and Antitumor Activity of Novel Dispiro[oxindole-cyclohexanone]- pyrrolidines

Current pharmaceutical design, 2022, Vol.28 (3), p.198

2022

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REV-ERB activation as a novel pharmacological approach for treating inflammatory pain

Frontiers in pharmacology, 2023-04, Vol.14, p.1171931-1171931

2023

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Metal coordinating inhibitors of Rift Valley fever virus replication

PloS one, 2022-09, Vol.17 (9), p.e0274266-e0274266

2022

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Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2201407-2201407

2023

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Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH

Metabolites, 2022-03, Vol.12 (3), p.238

2022

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Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

Biomedicines, 2022-02, Vol.10 (2), p.365

2022

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Catalyst-and organic solvent-free synthesis, structural, and theoretical studies of 1-arylidenamino-2,4-disubstituted-2-imidazoline-5-ones

Results in Chemistry, 2020-01, Vol.2, p.100042, Article 100042

2020

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Synthesis and Evaluation of Troponoids as a New Class of Antibiotics

ACS omega, 2018-11, Vol.3 (11), p.15125-15133

2018

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Synthesis of 3-Aminoquinazolinones via a SnCl 2 -Mediated ANRORC-like Reductive Rearrangement of 1,3,4-Oxadiazoles

Journal of organic chemistry, 2023-12, Vol.88 (24), p.17062-17068

2023

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Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Journal of medicinal chemistry, 2021-12, Vol.64 (24), p.17545-17571

2021

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Catalyst- and organic solvent-free synthesis of thioacids in water

Tetrahedron letters, 2019-07, Vol.60 (30), p.2018-2021

2019

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Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH 2 insertion

RSC advances, 2021-02, Vol.11 (13), p.7564-7569

2021

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Synthesis, assessment and corrosion protection investigations of some novel peptidomimetic cationic surfactants: Empirical and theoretical insights

Journal of molecular liquids, 2020-10, Vol.315, p.113672, Article 113672

2020

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Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH2 insertion

RSC advances, 2021-02, Vol.11 (13), p.7564-7569

2021

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A Synthetic ERR Agonist Alleviates Metabolic Syndrome

The Journal of pharmacology and experimental therapeutics, 2024-02, Vol.388 (2), p.232

2024

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Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH insertion

RSC advances, 2021-02, Vol.11 (13), p.7564-7569

2021

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4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments

European journal of medicinal chemistry, 2023-03, Vol.250, p.115180-115180, Article 115180

2023

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Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

The Journal of biological chemistry, 2022-02, Vol.298 (2), p.101554-101554, Article 101554

2022

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Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

ACS chemical biology, 2023-04, Vol.18 (4), p.756-771

2023

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Tailoring FXR Modulators for Intestinal Specificity: Recent Progress and Insights

REV-ERB agonism improves liver pathology in a mouse model of NASH

2,5-Diketopiperazines (DKPs): Promising Scaffolds for Anticancer Agents

Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease

Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases

Design, Synthesis and Antitumor Activity of Novel Dispiro[oxindole-cyclohexanone]- pyrrolidines

REV-ERB activation as a novel pharmacological approach for treating inflammatory pain

Metal coordinating inhibitors of Rift Valley fever virus replication

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights

Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH

Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening

Catalyst-and organic solvent-free synthesis, structural, and theoretical studies of 1-arylidenamino-2,4-disubstituted-2-imidazoline-5-ones

Synthesis and Evaluation of Troponoids as a New Class of Antibiotics

Synthesis of 3-Aminoquinazolinones via a SnCl 2 -Mediated ANRORC-like Reductive Rearrangement of 1,3,4-Oxadiazoles

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor

Catalyst- and organic solvent-free synthesis of thioacids in water

Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH 2 insertion

Synthesis, assessment and corrosion protection investigations of some novel peptidomimetic cationic surfactants: Empirical and theoretical insights

Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH2 insertion

A Synthetic ERR Agonist Alleviates Metabolic Syndrome

Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH insertion

4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

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