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Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets

Pharmacological reviews, 2009-03, Vol.61 (1), p.9-38

2009

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Endogenous bufadienolides, mineralocorticoid receptor antagonists and fibrosis in chronic kidney disease

Frontiers in pharmacology, 2024-09, Vol.15, p.1431216

2024

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Chronic α1-Na/K-ATPase inhibition reverses the elongation of the axon initial segment of the hippocampal CA1 pyramidal neurons in Angelman syndrome model mice

Neuropsychopharmacology (New York, N.Y.), 2021-02, Vol.46 (3), p.654-664

2021

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Fli1 and Tissue Fibrosis in Various Diseases

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1881

2023

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Antibody to Endogenous Cardiotonic Steroid Reverses Vascular Fibrosis and Restores Vasorelaxation in Chronic Kidney Disease

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8896

2024

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Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats

International journal of molecular sciences, 2018-10, Vol.19 (10), p.3168

2018

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Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1941

2021

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High salt is a risk factor for cardiovascular and kidney diseases. What is next, fibrosis?

Journal of hypertension, 2021-07, Vol.39 (7), p.1309-1310

Bagrov, Alexei Y.

2021

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Silencing of PKG1 Gene Mimics Effect of Aging and Sensitizes Rat Vascular Smooth Muscle Cells to Cardiotonic Steroids: Impact on Fibrosis and Salt Sensitivity

Journal of the American Heart Association, 2023-06, Vol.12 (12), p.e028768-e028768

2023

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Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3336

2022

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Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4563

2022

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Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na⁺/K⁺-ATPase Profibrotic Signaling Pathways

International journal of molecular sciences, 2018-08, Vol.19 (9), p.2566

2018

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Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure

American journal of hypertension, 2012-06, Vol.25 (6), p.690-696

2012

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Model of Chronic Thromboembolic Pulmonary Hypertension in Rats Caused by Repeated Intravenous Administration of Partially Biodegradable Sodium Alginate Microspheres

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1149

2021

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The Pressure of Aging

The Medical clinics of North America, 2017-01, Vol.101 (1), p.81-101

2017

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Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness

Clinical journal of the American Society of Nephrology, 2013-11, Vol.8 (11), p.1952-1959

2013

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Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

International journal of molecular sciences, 2018-08, Vol.19 (8), p.2377

2018

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Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension

Journal of the American Heart Association, 2019-10, Vol.8 (20), p.e012138-e012138

2019

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Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro‐Fibrotic Signaling

Journal of the American Heart Association, 2016-10, Vol.5 (10), p.n/a

2016

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Endogenous Bufadienolide, Blood Pressure and Alcohol Withdrawal

Current hypertension reviews, 2021-01, Vol.17 (2), p.170-173

2021

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Endogenous cardiotonic steroids in chronic renal failure

Nephrology, dialysis, transplantation, 2011-09, Vol.26 (9), p.2912-2919

2011

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High salt intake causes adverse fetal programming—vascular effects beyond blood pressure

Nephrology, dialysis, transplantation, 2012-09, Vol.27 (9), p.3464-3476

2012

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P.6.a.003 Spironolactone suppresses ethanol-seeking behavior and relapse in rats

European neuropsychopharmacology, 2013-10, Vol.23, p.S553-S554

2013

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Renal Ischemia Regulates Marinobufagenin Release in Humans

Hypertension (Dallas, Tex. 1979), 2010-11, Vol.56 (5), p.914-919

2010

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Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

Hypertension (Dallas, Tex. 1979), 2009-12, Vol.54 (6), p.1313-1320

2009

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Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets

Endogenous bufadienolides, mineralocorticoid receptor antagonists and fibrosis in chronic kidney disease

Chronic α1-Na/K-ATPase inhibition reverses the elongation of the axon initial segment of the hippocampal CA1 pyramidal neurons in Angelman syndrome model mice

Fli1 and Tissue Fibrosis in Various Diseases

Antibody to Endogenous Cardiotonic Steroid Reverses Vascular Fibrosis and Restores Vasorelaxation in Chronic Kidney Disease

Dietary Sodium Restriction Reduces Arterial Stiffness, Vascular TGF-β-Dependent Fibrosis and Marinobufagenin in Young Normotensive Rats

Preeclampsia: Cardiotonic Steroids, Fibrosis, Fli1 and Hint to Carcinogenesis

High salt is a risk factor for cardiovascular and kidney diseases. What is next, fibrosis?

Silencing of PKG1 Gene Mimics Effect of Aging and Sensitizes Rat Vascular Smooth Muscle Cells to Cardiotonic Steroids: Impact on Fibrosis and Salt Sensitivity

Canrenone Restores Vasorelaxation Impaired by Marinobufagenin in Human Preeclampsia

Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats

Telocinobufagin, a Novel Cardiotonic Steroid, Promotes Renal Fibrosis via Na⁺/K⁺-ATPase Profibrotic Signaling Pathways

Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure

Model of Chronic Thromboembolic Pulmonary Hypertension in Rats Caused by Repeated Intravenous Administration of Partially Biodegradable Sodium Alginate Microspheres

The Pressure of Aging

Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness

Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro‐Fibrotic Signaling

Endogenous Bufadienolide, Blood Pressure and Alcohol Withdrawal

Endogenous cardiotonic steroids in chronic renal failure

High salt intake causes adverse fetal programming—vascular effects beyond blood pressure

P.6.a.003 Spironolactone suppresses ethanol-seeking behavior and relapse in rats

Renal Ischemia Regulates Marinobufagenin Release in Humans

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

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