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Endothelin 1 in cancer: biological implications and therapeutic opportunities

Nature reviews. Cancer, 2013-09, Vol.13 (9), p.637-651

2013

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Endothelin therapeutics in cancer: Where are we?

American journal of physiology. Regulatory, integrative and comparative physiology, 2016-03, Vol.310 (6), p.R469-R475

2016

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New Routes in GPCR/β-Arrestin-Driven Signaling in Cancer Progression and Metastasis

Frontiers in pharmacology, 2019-02, Vol.10, p.114-114

2019

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YAP and endothelin-1 signaling: an emerging alliance in cancer

Journal of experimental & clinical cancer research, 2021-01, Vol.40 (1), p.27-27, Article 27

2021

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The endothelin axis as therapeutic target in human malignancies: present and future

Current pharmaceutical design, 2012, Vol.18 (19), p.2720-2733

Bagnato, Anna

2012

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β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer

Nature communications, 2019-07, Vol.10 (1), p.3196-15, Article 3196

2019

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The endothelin axis: emerging role in cancer

Nature reviews. Cancer, 2003-02, Vol.3 (2), p.110-116

2003

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Tumor Cellular and Microenvironmental Cues Controlling Invadopodia Formation

Frontiers in cell and developmental biology, 2020-10, Vol.8, p.584181-584181

2020

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Targeting Endothelin-1 Receptor/β-Arrestin-1 Axis in Ovarian Cancer: From Basic Research to a Therapeutic Approach

Frontiers in endocrinology (Lausanne), 2019-09, Vol.10

2019

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Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

Journal of experimental & clinical cancer research, 2022-04, Vol.41 (1), p.157-157, Article 157

2022

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Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition

Cell death & disease, 2023-01, Vol.14 (1), p.5-14, Article 5

2023

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The β-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential

Cell death & disease, 2024-05, Vol.15 (5), p.358-358, Article 358

2024

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Endothelin receptors as novel targets in tumor therapy

Journal of translational medicine, 2004-05, Vol.2 (1), p.16-16, Article 16

2004

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β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2806-2811

2009

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The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

Cell death & disease, 2023-01, Vol.14 (1), p.73-73, Article 73

2023

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Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells

Journal of molecular medicine (Berlin, Germany), 2013-03, Vol.91 (3), p.395-405

2013

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HSF-1/miR-145-5p transcriptional axis enhances hyperthermic intraperitoneal chemotherapy efficacy on peritoneal ovarian carcinosis

Cell death & disease, 2023-08, Vol.14 (8), p.535-535, Article 535

2023

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Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis

Life sciences (1973), 2016-08, Vol.159, p.43-48

2016

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Targeting the Endothelin-1 Receptors Curtails Tumor Growth and Angiogenesis in Multiple Myeloma

Frontiers in oncology, 2021-01, Vol.10, p.600025-600025

2021

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Epithelial-Mesenchymal Transition in Ovarian Cancer Progression: A Crucial Role for the Endothelin Axis

Cells, tissues, organs, 2007-01, Vol.185 (1-3), p.85-94

2007

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Endothelin‐1 receptor blockade as new possible therapeutic approach in multiple myeloma

British journal of haematology, 2017-09, Vol.178 (5), p.781-793

2017

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Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (24), p.11649-11657

2005

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The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer

American journal of physiology. Regulatory, integrative and comparative physiology, 2010-08, Vol.299 (2), p.R395-R404

2010

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Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade

Cancer research (Chicago, Ill.), 2009-03, Vol.69 (6), p.2669-2676

2009

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Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis

Frontiers in cell and developmental biology, 2021-12, Vol.9, p.764375-764375

2021

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Endothelin 1 in cancer: biological implications and therapeutic opportunities

Endothelin therapeutics in cancer: Where are we?

New Routes in GPCR/β-Arrestin-Driven Signaling in Cancer Progression and Metastasis

YAP and endothelin-1 signaling: an emerging alliance in cancer

The endothelin axis as therapeutic target in human malignancies: present and future

β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer

The endothelin axis: emerging role in cancer

Tumor Cellular and Microenvironmental Cues Controlling Invadopodia Formation

Targeting Endothelin-1 Receptor/β-Arrestin-1 Axis in Ovarian Cancer: From Basic Research to a Therapeutic Approach

Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition

The β-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential

Endothelin receptors as novel targets in tumor therapy

β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis

The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells

HSF-1/miR-145-5p transcriptional axis enhances hyperthermic intraperitoneal chemotherapy efficacy on peritoneal ovarian carcinosis

Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis

Targeting the Endothelin-1 Receptors Curtails Tumor Growth and Angiogenesis in Multiple Myeloma

Epithelial-Mesenchymal Transition in Ovarian Cancer Progression: A Crucial Role for the Endothelin Axis

Endothelin‐1 receptor blockade as new possible therapeutic approach in multiple myeloma

Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells

The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer

Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade

Ovarian Cancer-Driven Mesothelial-to-Mesenchymal Transition is Triggered by the Endothelin-1/β-arr1 Axis

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