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Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau

Neuropsychopharmacology (New York, N.Y.), 2021-01, Vol.46 (1), p.98-115

2021

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Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain

Nature communications, 2022-05, Vol.13 (1), p.2927-18, Article 2927

2022

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Copper(I)-nitrene platform for chemoproteomic profiling of methionine

Nature communications, 2024-05, Vol.15 (1), p.4243-4243, Article 4243

2024

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Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway

Scientific reports, 2021-10, Vol.11 (1), p.20576-20576, Article 20576

2021

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Robust Affinity Standards for Cu(I) Biochemistry

Journal of the American Chemical Society, 2013-12, Vol.135 (49), p.18549-18559

2013

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A conserved switch controls virulence, sporulation, and motility in C. difficile

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012224-e1012224

2024

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Designed To Dissolve: Suppression of Colloidal Aggregation of Cu(I)-Selective Fluorescent Probes in Aqueous Buffer and In-Gel Detection of a Metallochaperone

Journal of the American Chemical Society, 2011-10, Vol.133 (40), p.15906-15909

2011

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Characterization of US population levels of urinary methylcarbamoyl mercapturic acid, a metabolite of N,N-dimethylformamide and methyl isocyanate, in the National Health and Nutrition Examination Survey (NHANES) 2005–2006 and 2011–2016

Environmental science and pollution research international, 2021-04, Vol.28 (13), p.16781-16791

2021

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Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease

Biomolecules (Basel, Switzerland), 2024-01, Vol.14 (1), p.66

2024

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Dynamic Redox Regulation of IL-4 Signaling

PLoS computational biology, 2015-11, Vol.11 (11), p.e1004582-e1004582

2015

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Loss of cardiac myosin light chain kinase contributes to contractile dysfunction in right ventricular pressure overload

Physiological reports, 2022-04, Vol.10 (7), p.e15238-n/a

2022

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Defining the ligand-dependent proximatome of the sigma 1 receptor

Frontiers in cell and developmental biology, 2023-06, Vol.11, p.1045759-1045759

2023

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Regulation of the intestinal Na + /H + exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563

American Journal of Physiology: Cell Physiology, 2024-01, Vol.326 (1), p.C50-C59

2024

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In Situ Imaging of Metals in Cells and Tissues

Chemical reviews, 2009-10, Vol.109 (10), p.4780-4827

2009

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Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis

Blood, 2020-11, Vol.136 (Supplement 1), p.14-14

2020

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Exploring the multimeric tau interactome and its convergence with human tauopathy

Alzheimer's & dementia, 2023-12, Vol.19 (S13), p.n/a

2023

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Establishing the Role of EPS15, DVL2 and Cortactin in CALM-AF10 Leukemogenesis

Blood, 2021-11, Vol.138 (Supplement 1), p.3312-3312

2021

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The tauopathy‐associated PERK variant, PERK‐B, induces maladaptive translation and reveals novel pathogenic mechanisms of PSP

Alzheimer's & dementia, 2023-12, Vol.19 (S24), p.n/a

2023

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Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines

Molecular & cellular proteomics, 2023-06, Vol.22 (6), p.100546, Article 100546

2023

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The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer’s Disease

Alzheimer's & dementia, 2023-12, Vol.19 (S12), p.n/a

2023

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Proximity-based labeling reveals DNA damage–induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome

The Journal of biological chemistry, 2022-08, Vol.298 (8), p.102135, Article 102135

2022

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Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia

Molecular & cellular proteomics, 2024-08, Vol.23 (8), p.100809, Article 100809

2024

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Retromer subunit, VPS29, regulates vacuolar‐type ATPase and lysosomal acidification in the aging brain

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Crotonaldehyde exposure in U.S. tobacco smokers and nonsmokers: NHANES 2005–2006 and 2011–2012

Environmental research, 2018-05, Vol.163 (C), p.1-9

2018

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Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau

Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain

Copper(I)-nitrene platform for chemoproteomic profiling of methionine

Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway

Robust Affinity Standards for Cu(I) Biochemistry

Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis

A conserved switch controls virulence, sporulation, and motility in C. difficile

Designed To Dissolve: Suppression of Colloidal Aggregation of Cu(I)-Selective Fluorescent Probes in Aqueous Buffer and In-Gel Detection of a Metallochaperone

Characterization of US population levels of urinary methylcarbamoyl mercapturic acid, a metabolite of N,N-dimethylformamide and methyl isocyanate, in the National Health and Nutrition Examination Survey (NHANES) 2005–2006 and 2011–2016

Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease

Dynamic Redox Regulation of IL-4 Signaling

Loss of cardiac myosin light chain kinase contributes to contractile dysfunction in right ventricular pressure overload

Defining the ligand-dependent proximatome of the sigma 1 receptor

Regulation of the intestinal Na + /H + exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563

In Situ Imaging of Metals in Cells and Tissues

Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis

Exploring the multimeric tau interactome and its convergence with human tauopathy

Establishing the Role of EPS15, DVL2 and Cortactin in CALM-AF10 Leukemogenesis

The tauopathy‐associated PERK variant, PERK‐B, induces maladaptive translation and reveals novel pathogenic mechanisms of PSP

Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines

The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer’s Disease

Proximity-based labeling reveals DNA damage–induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome

Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia

Retromer subunit, VPS29, regulates vacuolar‐type ATPase and lysosomal acidification in the aging brain

Crotonaldehyde exposure in U.S. tobacco smokers and nonsmokers: NHANES 2005–2006 and 2011–2012

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