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Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3

Cancer Immunology, Immunotherapy, 2006-07, Vol.55 (7), p.785-796

2006

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T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

Cancer Immunology, Immunotherapy, 2006-05, Vol.55 (5), p.503-514

2006

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High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G

Molecular Immunology, 2006-03, Vol.43 (8), p.1183-1193

2006

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MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors

Molecular Immunology, 2006-03, Vol.43 (8), p.1129-1143

2006

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Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells

Molecular immunology, 2006-02, Vol.43 (6), p.763-771

2006

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Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers

British journal of cancer, 2006-01, Vol.94 (1), p.128-135

2006

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Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma

Hepatology research, 2006, Vol.34 (1), p.50-56

2006

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BiTEs: bispecific antibody constructs with unique anti-tumor activity

Drug discovery today, 2005-09, Vol.10 (18), p.1237-1244

2005

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Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct

International journal of cancer, 2005-05, Vol.115 (1), p.98-104

2005

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Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy

Cancer Immunology, Immunotherapy, 2005-05, Vol.54 (5), p.431-445

2005

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Highly efficient antigen targeting to M-DC8+ dendritic cells via FcγRIII/CD16-specific antibody conjugates

International immunology, 2005-05, Vol.17 (5), p.539-547

2005

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Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (7), p.2882-2889

2005

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Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty

The FASEB journal, 2005-02, Vol.19 (2), p.246-248

2005

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Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

British journal of cancer, 2005-01, Vol.92 (2), p.342-349

2005

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A bispecific single-chain antibody fusion protein for targeted depletion of autoreactive B cells via unstimulated human T lymphocytes

Molecular immunology, 2004-07, Vol.41 (5), p.511-518

2004

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A revival of bispecific antibodies

Trends in biotechnology (Regular ed.), 2004-05, Vol.22 (5), p.238-244

2004

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Rapamycin Effects Transcriptional Programs in Smooth Muscle Cells Controlling Proliferative and Inflammatory Properties

Molecular pharmacology, 2004-04, Vol.65 (4), p.880-889

2004

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Bispecific antibodies for polyclonal T-cell engagement

Current opinion in molecular therapeutics, 2003-08, Vol.5 (4), p.413

2003

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Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo

International immunology, 2003-07, Vol.15 (7), p.789-796

2003

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Efficient tumor cell lysis by autologous, tumor‐resident T lymphocytes in primary ovarian cancer samples by an EP‐CAM‐/CD3‐bispecific antibody

International journal of cancer, 2003-06, Vol.105 (2), p.241-248

2003

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Cytotoxic activity of novel human monoclonal antibody MT201 against primary ovarian tumor cells

Journal of cancer research and clinical oncology, 2003-06, Vol.129 (6), p.341-348

2003

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A subset of human dendritic cells in the T cell area of mucosa-associated lymphoid tissue with a high potential to produce TNF-alpha

The Journal of immunology (1950), 2003-05, Vol.170 (10), p.5089-5094

2003

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Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19 anti-CD3 single-chain antibody construct

Leukemia, 2003-05, Vol.17 (5), p.900-909

2003

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T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

The Journal of immunology (1950), 2003-04, Vol.170 (8), p.4397-4402

2003

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Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

International journal of cancer, 2002-08, Vol.100 (6), p.690-697

2002

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Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3

T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G

MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors

Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells

Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers

Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma

BiTEs: bispecific antibody constructs with unique anti-tumor activity

Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct

Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy

Highly efficient antigen targeting to M-DC8+ dendritic cells via FcγRIII/CD16-specific antibody conjugates

Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct

Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

A bispecific single-chain antibody fusion protein for targeted depletion of autoreactive B cells via unstimulated human T lymphocytes

A revival of bispecific antibodies

Rapamycin Effects Transcriptional Programs in Smooth Muscle Cells Controlling Proliferative and Inflammatory Properties

Bispecific antibodies for polyclonal T-cell engagement

Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo

Efficient tumor cell lysis by autologous, tumor‐resident T lymphocytes in primary ovarian cancer samples by an EP‐CAM‐/CD3‐bispecific antibody

Cytotoxic activity of novel human monoclonal antibody MT201 against primary ovarian tumor cells

A subset of human dendritic cells in the T cell area of mucosa-associated lymphoid tissue with a high potential to produce TNF-alpha

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19 anti-CD3 single-chain antibody construct

T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

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