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In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei

Molecules (Basel, Switzerland), 2020-04, Vol.25 (8), p.1980

2020

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Identification of Novel Flavonoids and Ansa-Macrolides with Activities against Leishmania donovani through Natural Product Library Screening

Pathogens (Basel), 2024-02, Vol.13 (3), p.213

2024

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Autophagy-regulating small molecules and their therapeutic applications

Chemical Society reviews, 2012-04, Vol.41 (8), p.3245-3263

2012

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Infectivity and Drug Susceptibility Profiling of Different Leishmania -Host Cell Combinations

Pathogens (Basel), 2020-05, Vol.9 (5), p.393

2020

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In Vivo Efficacy of SQ109 against Leishmania donovani , Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites

Biomedicines, 2022-03, Vol.10 (3), p.670

2022

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Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms

Cell chemical biology, 2018-10, Vol.25 (10), p.1242-1254.e8

2018

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A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

Nature chemistry, 2017-07, Vol.9 (7), p.667-675

2017

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Fluorophore-labeled, Peptide-based Glycoclusters: Synthesis, Binding Properties for Lectins, and Detection of Carbohydrate-Binding Proteins in Cells

Chemistry, an Asian journal, 2011-08, Vol.6 (8), p.2107-2113

2011

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Fluorescent Zinc Sensor with Minimized Proton-Induced Interferences: Photophysical Mechanism for Fluorescence Turn-On Response and Detection of Endogenous Free Zinc Ions

Inorganic chemistry, 2012-08, Vol.51 (16), p.8760-8774

2012

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Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits

Biochemical and biophysical research communications, 2021-09, Vol.569, p.193-198

2021

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Dual-targeting delivery system for selective cancer cell death and imaging

Chemical science (Cambridge), 2013-01, Vol.4 (3), p.947-956

2013

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A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo

Tetrahedron, 2010-06, Vol.66 (23), p.4016-4021

2010

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A Small Molecule That Binds to an ATPase Domain of Hsc70 Promotes Membrane Trafficking of Mutant Cystic Fibrosis Transmembrane Conductance Regulator

Journal of the American Chemical Society, 2011-12, Vol.133 (50), p.20267-20276

2011

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Targeted Enzyme-Responsive Drug Carriers: Studies on the Delivery of a Combination of Drugs

Angewandte Chemie (International ed.), 2004-03, Vol.43 (13), p.1675-1678

2004

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Complete reductive dechlorination of tetrachloroethene to ethene by anaerobic microbial enrichment culture developed from sediment

Biotechnology letters, 2010-12, Vol.32 (12), p.1829-1835

2010

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Repurposing of conformationally-restricted cyclopentane-based AKT–inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine

Bioorganic chemistry, 2023-12, Vol.141, p.106890-106890, Article 106890

2023

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Heavy metal concentrations and enzyme activities in soil from a contaminated Korean shooting range

Journal of bioscience and bioengineering, 2002, Vol.94 (5), p.406-411

2002

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A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

Scientific reports, 2015-12, Vol.5 (1), p.17642-17642, Article 17642

2015

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Monitoring Bacterial Population Dynamics Using Real-Time PCR During the Bioremediation of Crude-Oil-Contaminated Soil

Journal of Microbiology and Biotechnology, 2009, 19(4), , pp.339-345

2009

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Dual-labeled glycoclusters: synthesis and their application in monitoring lectin-mediated endocytosis

Molecular bioSystems, 2013-05, Vol.9 (5), p.978-986

2013

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High extracellular calcium-induced NFATc3 regulates the expression of receptor activator of NF-κB ligand in osteoblasts

Bone (New York, N.Y.), 2011-08, Vol.49 (2), p.242-249

2011

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Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites

ACS infectious diseases, 2023-02, Vol.9 (2), p.342-364

2023

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A Small Molecule Inhibitor of ATPase Activity of HSP70 Induces Apoptosis and Has Antitumor Activities

Chemistry & biology, 2015-03, Vol.22 (3), p.391-403

2015

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Biodegradation of ethylene dibromide (1,2-dibromoethane [EDB]) in microcosms simulating in situ and biostimulated conditions

Journal of hazardous materials, 2012-03, Vol.209-210, p.92-98

2012

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Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor

Journal of the American Chemical Society, 2010-01, Vol.132 (2), p.601-610

2010

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In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei

Identification of Novel Flavonoids and Ansa-Macrolides with Activities against Leishmania donovani through Natural Product Library Screening

Autophagy-regulating small molecules and their therapeutic applications

Infectivity and Drug Susceptibility Profiling of Different Leishmania -Host Cell Combinations

In Vivo Efficacy of SQ109 against Leishmania donovani , Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites

Subcellular Hsp70 Inhibitors Promote Cancer Cell Death via Different Mechanisms

A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

Fluorophore-labeled, Peptide-based Glycoclusters: Synthesis, Binding Properties for Lectins, and Detection of Carbohydrate-Binding Proteins in Cells

Fluorescent Zinc Sensor with Minimized Proton-Induced Interferences: Photophysical Mechanism for Fluorescence Turn-On Response and Detection of Endogenous Free Zinc Ions

Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits

Dual-targeting delivery system for selective cancer cell death and imaging

A selenolactone-based fluorescent chemodosimeter to monitor mecury/methylmercury species in vitro and in vivo

A Small Molecule That Binds to an ATPase Domain of Hsc70 Promotes Membrane Trafficking of Mutant Cystic Fibrosis Transmembrane Conductance Regulator

Targeted Enzyme-Responsive Drug Carriers: Studies on the Delivery of a Combination of Drugs

Complete reductive dechlorination of tetrachloroethene to ethene by anaerobic microbial enrichment culture developed from sediment

Repurposing of conformationally-restricted cyclopentane-based AKT–inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine

Heavy metal concentrations and enzyme activities in soil from a contaminated Korean shooting range

A small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens

Monitoring Bacterial Population Dynamics Using Real-Time PCR During the Bioremediation of Crude-Oil-Contaminated Soil

Dual-labeled glycoclusters: synthesis and their application in monitoring lectin-mediated endocytosis

High extracellular calcium-induced NFATc3 regulates the expression of receptor activator of NF-κB ligand in osteoblasts

Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites

A Small Molecule Inhibitor of ATPase Activity of HSP70 Induces Apoptosis and Has Antitumor Activities

Biodegradation of ethylene dibromide (1,2-dibromoethane [EDB]) in microcosms simulating in situ and biostimulated conditions

Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor

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