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Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

International journal of molecular sciences, 2023-06, Vol.24 (13), p.10810

2023

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Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease

The Journal of pharmacology and experimental therapeutics, 2015-01, Vol.352 (1), p.110-118

2015

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Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

Journal of Alzheimer's disease, 2019-01, Vol.72 (3), p.931-946

2019

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Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Journal of Alzheimer's disease, 2020-01, Vol.75 (2), p.501-519

2020

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A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

Frontiers in molecular neuroscience, 2018-01, Vol.10, p.447-447

2018

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Crystal structures and Hirshfeld surface analyses of the di- and tri-hydrates of (5α,17E)-17-hydrazonoandrostan-3-ol: Significant differences in the hydrogen bonding patterns and supramolecular arrangements

Steroids, 2018-12, Vol.140, p.92-103

2018

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In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Frontiers in immunology, 2017-10, Vol.8, p.1361-1361

2017

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HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

Biomedicines, 2022-04, Vol.10 (4), p.867

2022

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Novel Method of Analysis for the Determination of Residual Formaldehyde by High-Performance Liquid Chromatography

International journal of analytical chemistry, 2022-09, Vol.2022, p.1-10

2022

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N '-(1,3-Benzo-thia-zol-2-yl)benzene-sulfono-hydrazide: crystal structure, Hirshfeld surface analysis and computational chemistry

Acta crystallographica. Section E, Crystallographic communications, 2019-04, Vol.75 (Pt 4), p.516-523

2019

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Variation in supramolecular arrangements of hydrazones, o-H2NC6H4CMeNNHC6H4X (XH, o-, m- and p-NO2), derived from o-aminoacetophenone and phenylhydrazines

Journal of molecular structure, 2012-08, Vol.1020, p.16-22

2012

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N ′-(1,3-Benzothiazol-2-yl)benzenesulfonohydrazide: crystal structure, Hirshfeld surface analysis and computational chemistry

Acta crystallographica. Section E, Crystallographic communications, 2019-04, Vol.75 (4), p.516-523

2019

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Synthesis of Per- and Poly-Substituted Trehalose Derivatives: Studies of Properties Relevant to Their Use as Excipients for Controlled Drug Release

Journal of carbohydrate chemistry, 2009-05, Vol.28 (4), p.198-221

2009

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(Pyrazinecarbonyl)hydrazone halobenzaldehydes: supramolecular arrays generated by face to face stacking of ribbons, formed from C–H–O interactions

Zeitschrift für Kristallographie, 2009-01, Vol.224 (10)

2009

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Cysteine-Independent Inhibition of Alzheimer's Disease-like Paired Helical Filament Assembly by Leuco-Methylthioninium (LMT)

Journal of molecular biology, 2018-10, Vol.430 (21), p.4119-4131

2018

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Crystal structures and Hirshfeld surface analyses of a des-A-B-aromatic steroidal compound, and two of its derivatives, having a trans -2,3,4,5-tetrahydro-3 a -methyl-7-methoxybenz[ e ]indane skeleton – structural comparisons with reported tetrahydrobenz[ e ]indene derivatives

Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2019-09, Vol.74 (9), p.649-663

2019

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Synthesis, potent anti-TB activity against M. tuberculosis ATTC 27294, crystal structures and complex formation of selected 2-arylidenehydrazinylbenzothiazole derivatives

Journal of molecular structure, 2019-02, Vol.1178, p.655-668

2019

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Supramolecular structures of substituted α,α′-trehalose derivatives

Acta crystallographica. Section B, Structural science, 2004-08, Vol.60 (4), p.461-471

2004

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Co-crystallised α- and β-Anomers of 2,3,4,6-Tetra-acetyl-d-glucopyranose, in which the α- and β-Anomers are Randomly Distributed in the Hydrogen-bonded Chains of Molecules

Journal of chemical crystallography, 2007-12, Vol.37 (12), p.853-858

2007

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1,2,3,4-Tetra-O-acetyl-β-d-glucopyranuronic acid monohydrate at 120 K and anhydrous 1,2,3,4-tetra-O-acetyl-β-d-glucopyranose at 292 K

Acta crystallographica. Section C, Crystal structure communications, 2005-12, Vol.61 (12), p.o711-o714

2005

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1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic acid monohydrate at 120 K and anhydrous 1,2,3,4-tetra-O-acetyl-β-D-glucopyranose at 292 K

Acta crystallographica. Section C, Crystal structure communications, 2005-12, Vol.61 (Pt 12), p.o711-o714

2005

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Crystal structures of four 1-(aryl)-[1,2,4]triazolo[4,3-a]quinoxaline derivatives

Journal of molecular structure, 2017-01, Vol.1128, p.579-589

2017

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Crystal structures and Hirshfeld surface analyses of seven 7-aryl-4,7-dioxoheptanoic acids: differing carboxylic acid interactions leading to dimers, chains and three-dimensional arrays

Zeitschrift für Kristallographie. Crystalline materials, 2018-11, Vol.233 (11), p.761-780

2018

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A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

Tetrahedron, 2006-09, Vol.62 (37), p.8770-8778

2006

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Structural studies of ( E )-2-(benzylidene)-1-tetralone derivatives: crystal structures and Hirshfeld surface analysis

Zeitschrift für Kristallographie. Crystalline materials, 2017-10, Vol.232 (10), p.697-718

2017

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Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease

Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease

Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy

Crystal structures and Hirshfeld surface analyses of the di- and tri-hydrates of (5α,17E)-17-hydrazonoandrostan-3-ol: Significant differences in the hydrogen bonding patterns and supramolecular arrangements

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine

Novel Method of Analysis for the Determination of Residual Formaldehyde by High-Performance Liquid Chromatography

N '-(1,3-Benzo-thia-zol-2-yl)benzene-sulfono-hydrazide: crystal structure, Hirshfeld surface analysis and computational chemistry

Variation in supramolecular arrangements of hydrazones, o-H2NC6H4CMeNNHC6H4X (XH, o-, m- and p-NO2), derived from o-aminoacetophenone and phenylhydrazines

N ′-(1,3-Benzothiazol-2-yl)benzenesulfonohydrazide: crystal structure, Hirshfeld surface analysis and computational chemistry

Synthesis of Per- and Poly-Substituted Trehalose Derivatives: Studies of Properties Relevant to Their Use as Excipients for Controlled Drug Release

(Pyrazinecarbonyl)hydrazone halobenzaldehydes: supramolecular arrays generated by face to face stacking of ribbons, formed from C–H–O interactions

Cysteine-Independent Inhibition of Alzheimer's Disease-like Paired Helical Filament Assembly by Leuco-Methylthioninium (LMT)

Crystal structures and Hirshfeld surface analyses of a des-A-B-aromatic steroidal compound, and two of its derivatives, having a trans -2,3,4,5-tetrahydro-3 a -methyl-7-methoxybenz[ e ]indane skeleton – structural comparisons with reported tetrahydrobenz[ e ]indene derivatives

Synthesis, potent anti-TB activity against M. tuberculosis ATTC 27294, crystal structures and complex formation of selected 2-arylidenehydrazinylbenzothiazole derivatives

Supramolecular structures of substituted α,α′-trehalose derivatives

Co-crystallised α- and β-Anomers of 2,3,4,6-Tetra-acetyl-d-glucopyranose, in which the α- and β-Anomers are Randomly Distributed in the Hydrogen-bonded Chains of Molecules

1,2,3,4-Tetra-O-acetyl-β-d-glucopyranuronic acid monohydrate at 120 K and anhydrous 1,2,3,4-tetra-O-acetyl-β-d-glucopyranose at 292 K

1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic acid monohydrate at 120 K and anhydrous 1,2,3,4-tetra-O-acetyl-β-D-glucopyranose at 292 K

Crystal structures of four 1-(aryl)-[1,2,4]triazolo[4,3-a]quinoxaline derivatives

Crystal structures and Hirshfeld surface analyses of seven 7-aryl-4,7-dioxoheptanoic acids: differing carboxylic acid interactions leading to dimers, chains and three-dimensional arrays

A homologous series of eunicellin-based diterpenes from Acalycigorgia sp. characterised by tandem mass spectrometry

Structural studies of ( E )-2-(benzylidene)-1-tetralone derivatives: crystal structures and Hirshfeld surface analysis

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