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Clinical Studies on Drug–Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Clinical pharmacology and therapeutics, 2019-06, Vol.105 (6), p.1345-1361

2019

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Cytochrome P450 in Pharmacogenetics: An Update

Advances in pharmacology (1990), 2018, Vol.83, p.3-32

2018

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Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Pharmacological reviews, 2016-01, Vol.68 (1), p.168-241

2016

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Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans

Clinical pharmacology and therapeutics, 2021-12, Vol.110 (6), p.1622-1632

2021

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Comparison of LC-MS/MS and chemiluminescent immunoassays for immunosuppressive drugs reveals organ dependent variation in blood cyclosporine a concentrations

Clinica chimica acta, 2020-09, Vol.508, p.22-27

2020

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Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance

Clinical pharmacology and therapeutics, 2006-12, Vol.80 (6), p.565-581

2006

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Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

PloS one, 2019-04, Vol.14 (4), p.e0216029

2019

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VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (46), p.13144-13149

2016

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Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing

European journal of clinical pharmacology, 2015-04, Vol.71 (4), p.441-447

2015

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Professor Pertti Jaakko Neuvonen (25 August 1943‐14 May 2020)

Basic & clinical pharmacology & toxicology, 2021-04, Vol.128 (4), p.553-554

2021

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In vitro assessment of time-dependent inhibitory effects on CYP2C8 and CYP3A activity by fourteen protein kinase inhibitors

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1202-1209

2014

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Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications

Trends in pharmacological sciences (Regular ed.), 2012-06, Vol.33 (6), p.312-322

2012

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Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

Journal of controlled release, 2019-06, Vol.304, p.29-38

2019

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In vitro assessment of inhibitory effects of kinase inhibitors on CYP2C9, 3A and 1A2: Prediction of drug-drug interaction risk with warfarin and direct oral anticoagulants

European journal of pharmaceutical sciences, 2024-12, Vol.203, p.106884, Article 106884

2024

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Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.219-228

2019

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Drug‐related deaths in a university hospital: Comparison to previous decades

Basic & clinical pharmacology & toxicology, 2024-01, Vol.134 (1), p.165-174

2024

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Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel

Basic & clinical pharmacology & toxicology, 2022-01, Vol.130 (S1), p.48-59

2022

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Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin

Clinical pharmacokinetics, 2008-01, Vol.47 (7), p.463-474

2008

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Enantiospecific Pharmacogenomics of Fluvastatin

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.668-680

2019

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Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

Drug metabolism and disposition, 2023-03, Vol.51 (3), p.293-305

2023

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Incidence, preventability, and causality of adverse drug reactions at a university hospital emergency department

European journal of clinical pharmacology, 2021-04, Vol.77 (4), p.643-650

2021

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Effect of High‐Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long‐lasting Inhibition of CYP2C19

Clinical pharmacology and therapeutics, 2020-12, Vol.108 (6), p.1254-1264

2020

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A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics

British journal of clinical pharmacology, 2023-01, Vol.89 (1), p.242-252

2023

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Influence of Intravenous S-Ketamine on the Pharmacokinetics of Oral Morphine in Healthy Volunteers

Anesthesia and analgesia, 2024-03, Vol.138 (3), p.598

2024

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Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin

Clinical pharmacology and therapeutics, 2024-01, Vol.115 (1), p.71-79

2024

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Clinical Studies on Drug–Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Cytochrome P450 in Pharmacogenetics: An Update

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans

Comparison of LC-MS/MS and chemiluminescent immunoassays for immunosuppressive drugs reveals organ dependent variation in blood cyclosporine a concentrations

Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance

Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing

Professor Pertti Jaakko Neuvonen (25 August 1943‐14 May 2020)

In vitro assessment of time-dependent inhibitory effects on CYP2C8 and CYP3A activity by fourteen protein kinase inhibitors

Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications

Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

In vitro assessment of inhibitory effects of kinase inhibitors on CYP2C9, 3A and 1A2: Prediction of drug-drug interaction risk with warfarin and direct oral anticoagulants

Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

Drug‐related deaths in a university hospital: Comparison to previous decades

Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel

Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin

Enantiospecific Pharmacogenomics of Fluvastatin

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro

Incidence, preventability, and causality of adverse drug reactions at a university hospital emergency department

Effect of High‐Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long‐lasting Inhibition of CYP2C19

A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics

Influence of Intravenous S-Ketamine on the Pharmacokinetics of Oral Morphine in Healthy Volunteers

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin

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