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Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise

Current drug metabolism, 2006-01, Vol.7 (1), p.1

Bachmann, K A

2006

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In situ ToF-SIMS monitoring of SOFC cathodes – A case study of La0.74Sr0.17Mn1.01O2.9 model electrodes

Applied surface science, 2017-11, Vol.422, p.817-827

2017

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The use of in vitro methods to predict in vivo pharmacokinetics and drug interactions

Current drug metabolism, 2001-09, Vol.2 (3), p.299

2001

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Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans

Clinical pharmacology and therapeutics, 1999-06, Vol.65 (6), p.653-660

1999

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Differential kinetics of phenytoin in elderly patients

Drugs & aging, 1999-09, Vol.15 (3), p.235-250

1999

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Predicting inhibitory drug-drug interactions and evaluating drug interaction reports using inhibition constants

The Annals of pharmacotherapy, 2005-06, Vol.39 (6), p.1064

2005

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Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo

Xenobiotica, 1993, Vol.23 (3), p.307-315

1993

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Lack of Pharmacokinetic Interaction between Rofecoxib and Methotrexate in Rheumatoid Arthritis Patients

Journal of clinical pharmacology, 2001-10, Vol.41 (10), p.1120-1130

2001

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Influence of Some Novel N-Substituted Azoles and Pyridines on Rat Hepatic CYP3A Activity

Biochemical pharmacology, 1998-06, Vol.55 (11), p.1881-1892

1998

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Pharmacology: Principles and Practice

1, 2009

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The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo

Pharmacology, 1995-03, Vol.50 (3), p.146

1995

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Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity

British journal of clinical pharmacology, 1993-10, Vol.36 (4), p.380-382

1993

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Ethosuximide is primarily metabolized by CYP3A when incubated with isolated rat liver microsomes

Drug metabolism and disposition, 1998-01, Vol.26 (1), p.78

1998

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An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats

The Journal of pharmacology and experimental therapeutics, 1998-07, Vol.286 (1), p.561

1998

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The use of single-sample clearance estimates to probe hepatic drug metabolism in rats. IV. A model for possible application to phenotyping xenobiotic influences on human drug metabolism

Xenobiotica, 1989, Vol.19 (12), p.1449-1459

Bachmann, K. A.

1989

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Multiple-dose pharmacokinetics of intravenously administered cefoperazone and sulbactam when given in combination to infected, seriously ill, elderly patients

Antimicrobial Agents and Chemotherapy, 1988-05, Vol.32 (5), p.730-735

1988

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The use of single sample clearance estimates to probe hepatic drug metabolism: Handprinting the influence of phenobarbitone on human hepatic drug metabolism

Xenobiotica, 1991, Vol.21 (10), p.1385-1392

1991

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Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats

Pharmacology, 1983-01, Vol.27 (5), p.281

1983

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Exercise training does not alter cytochrome P-450 content and microsomal metabolism

Medicine and science in sports and exercise, 1994-08, Vol.26 (8), p.978-982

1994

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The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances

Xenobiotica, 1992, Vol.22 (1), p.27-31

1992

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New guidelines on chronic pancreatitis : interdisciplinary treatment strategies

Chirurg, 2013-02, Vol.84 (2), p.99

2013

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Accuracy of two equations in determining normalized phenytoin concentrations

DICP (Cincinnati, Ohio), 1989-01, Vol.23 (1), p.64

1989

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The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism

Xenobiotica, 1990, Vol.20 (5), p.537-547

1990

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The Suitability of Carbamazepine as a Single-Sample Probe of Human Mixed Function Oxidase Activity

Xenobiotica, 1989, Vol.19 (7), p.711-719

1989

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The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II

Xenobiotica, 1988, Vol.18 (2), p.161-167

1988

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Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise

In situ ToF-SIMS monitoring of SOFC cathodes – A case study of La0.74Sr0.17Mn1.01O2.9 model electrodes

The use of in vitro methods to predict in vivo pharmacokinetics and drug interactions

Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans

Differential kinetics of phenytoin in elderly patients

Predicting inhibitory drug-drug interactions and evaluating drug interaction reports using inhibition constants

Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo

Lack of Pharmacokinetic Interaction between Rofecoxib and Methotrexate in Rheumatoid Arthritis Patients

Influence of Some Novel N-Substituted Azoles and Pyridines on Rat Hepatic CYP3A Activity

Pharmacology: Principles and Practice

The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo

Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity

Ethosuximide is primarily metabolized by CYP3A when incubated with isolated rat liver microsomes

An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats

The use of single-sample clearance estimates to probe hepatic drug metabolism in rats. IV. A model for possible application to phenotyping xenobiotic influences on human drug metabolism

Multiple-dose pharmacokinetics of intravenously administered cefoperazone and sulbactam when given in combination to infected, seriously ill, elderly patients

The use of single sample clearance estimates to probe hepatic drug metabolism: Handprinting the influence of phenobarbitone on human hepatic drug metabolism

Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats

Exercise training does not alter cytochrome P-450 content and microsomal metabolism

The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances

New guidelines on chronic pancreatitis : interdisciplinary treatment strategies

Accuracy of two equations in determining normalized phenytoin concentrations

The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism

The Suitability of Carbamazepine as a Single-Sample Probe of Human Mixed Function Oxidase Activity

The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II

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