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Polypharmacology of dopamine receptor ligands

Progress in neurobiology, 2016-07, Vol.142, p.68-103

2016

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831: Induction of apoptosis by pyrrolo-1,5-benzoxazepines in oral squamous carcinoma cells

European journal of cancer (1990), 2014-07, Vol.50, p.S201-S201

2014

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Pre-clinical evaluation of a novel class of anti-cancer agents, the Pyrrolo-1, 5-benzoxazepines

Journal of Cancer, 2016-01, Vol.7 (15), p.2367-2377

2016

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PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells

British journal of cancer, 2011-01, Vol.104 (2), p.281-289

2011

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P.3.d.020 CAM24, a D3/5HT2a/5HT1a ligand reduces psychostimulant induced hyperactivity in mice without causing motor side effects

European neuropsychopharmacology, 2007, Vol.17, p.S484-S485

2007

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Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (sup1), p.98-109

2016

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Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663

Biochemistry (Easton), 2005-07, Vol.44 (28), p.9637-9644

2005

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Evolution of transmitted HIV‐1 drug resistance and viral subtypes circulation in Italy from 2006 to 2016

HIV medicine, 2018-10, Vol.19 (9), p.619-628

2018

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Long-term efficacy of dolutegravir in treatment-experienced subjects failing therapy with HIV-1 integrase strand inhibitor-resistant virus

Journal of antimicrobial chemotherapy, 2018-01, Vol.73 (1), p.177-182

2018

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A novel methodology for large-scale phylogeny partition

Nature communications, 2011, Vol.2 (1), p.321-321, Article 321

2011

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Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1919-1929

2005

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Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients

Clinical microbiology and infection, 2019-11, Vol.25 (11), p.1443-1446

2019

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Synthesis and Pharmacological Evaluation of Potent and Highly Selective D 3 Receptor Ligands: Inhibition of Cocaine-Seeking Behavior and the Role of Dopamine D 3 /D 2 Receptors

Journal of medicinal chemistry, 2003-08, Vol.46 (18), p.3822-3839

2003

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Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study

Open forum infectious diseases, 2018-06, Vol.5 (6), p.ofy113-ofy113

2018

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Burden of Disease in PWH Harboring a Multidrug-Resistant Virus: Data From the PRESTIGIO Registry

Open forum infectious diseases, 2020-11, Vol.7 (11), p.ofaa456-ofaa456

2020

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Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target

Journal of medicinal chemistry, 2005-06, Vol.48 (13), p.4367-4377

2005

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Maximizing plant species inventory efficiency by means of remotely sensed spectral distances

Global ecology and biogeography, 2005-09, Vol.14 (5), p.431-437

2005

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Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity

Journal of medicinal chemistry, 2005-11, Vol.48 (23), p.7153-7165

2005

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Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4362-4379

1999

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Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases

Current pharmaceutical design, 2003-01, Vol.9 (8), p.599-625

2003

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Novel Atypical Antipsychotic Agents: Rational Design, an Efficient Palladium-Catalyzed Route, and Pharmacological Studies

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1705-1708

2005

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Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010

Clinical microbiology and infection, 2012-08, Vol.18 (8), p.E299-E304

2012

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Duration of first-line antiretroviral therapy with tenofovir and emtricitabine combined with atazanavir/ritonavir, efavirenz or lopinavir/ritonavir in the Italian ARCA cohort

Journal of antimicrobial chemotherapy, 2013-01, Vol.68 (1), p.200-205

2013

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Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting

Journal of antimicrobial chemotherapy, 2009-09, Vol.64 (3), p.616-624

2009

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Polypharmacology of dopamine receptor ligands

831: Induction of apoptosis by pyrrolo-1,5-benzoxazepines in oral squamous carcinoma cells

Pre-clinical evaluation of a novel class of anti-cancer agents, the Pyrrolo-1, 5-benzoxazepines

PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells

P.3.d.020 CAM24, a D3/5HT2a/5HT1a ligand reduces psychostimulant induced hyperactivity in mice without causing motor side effects

Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors

Specific Targeting of Hepatitis C Virus NS3 RNA Helicase. Discovery of the Potent and Selective Competitive Nucleotide-Mimicking Inhibitor QU663

Evolution of transmitted HIV‐1 drug resistance and viral subtypes circulation in Italy from 2006 to 2016

Long-term efficacy of dolutegravir in treatment-experienced subjects failing therapy with HIV-1 integrase strand inhibitor-resistant virus

A novel methodology for large-scale phylogeny partition

Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors

Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients

Synthesis and Pharmacological Evaluation of Potent and Highly Selective D 3 Receptor Ligands: Inhibition of Cocaine-Seeking Behavior and the Role of Dopamine D 3 /D 2 Receptors

Impact of the M184V Resistance Mutation on Virological Efficacy and Durability of Lamivudine-Based Dual Antiretroviral Regimens as Maintenance Therapy in Individuals With Suppressed HIV-1 RNA: A Cohort Study

Burden of Disease in PWH Harboring a Multidrug-Resistant Virus: Data From the PRESTIGIO Registry

Pyrrolo[1,5]benzoxa(thia)zepines as a New Class of Potent Apoptotic Agents. Biological Studies and Identification of an Intracellular Location of Their Drug Target

Maximizing plant species inventory efficiency by means of remotely sensed spectral distances

Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity

Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

Neuronal high-affinity sodium-dependent glutamate transporters (EAATs): targets for the development of novel therapeutics against neurodegenerative diseases

Pyrrolo[1,3]benzothiazepine-Based Serotonin and Dopamine Receptor Antagonists. Molecular Modeling, Further Structure−Activity Relationship Studies, and Identification of Novel Atypical Antipsychotic Agents

Novel Atypical Antipsychotic Agents: Rational Design, an Efficient Palladium-Catalyzed Route, and Pharmacological Studies

Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010

Duration of first-line antiretroviral therapy with tenofovir and emtricitabine combined with atazanavir/ritonavir, efavirenz or lopinavir/ritonavir in the Italian ARCA cohort

Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting

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