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Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

Science (American Association for the Advancement of Science), 2009-07, Vol.325 (5939), p.433-433

2009

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The mast cell-B cell axis in lung vascular remodeling and pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2017-05, Vol.312 (5), p.L710-L721

2017

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TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

mAbs, 2021-01, Vol.13 (1), p.1890411

2021

Volltextzugriff (PDF)

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

mAbs, 2022-07, Vol.14 (1), p.2095949-2095949

2022

Volltextzugriff (PDF)

Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release

Journal for immunotherapy of cancer, 2021-06, Vol.9 (6), p.e002488

2021

Volltextzugriff (PDF)

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

Frontiers in immunology, 2018-04, Vol.9, p.889-889

2018

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Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

Genome research, 2014-08, Vol.24 (8), p.1371

2014

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Generation of gene-specific mutated rats using zinc-finger nucleases

Methods in molecular biology (Clifton, N.J.), 2010-01, Vol.597, p.211

2010

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Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity

mAbs, 2020-01, Vol.12 (1), p.1846900-1846900

2020

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Characterization of immunoglobulin heavy chain knockout rats

European journal of immunology, 2010-10, Vol.40 (10), p.2932-2941

2010

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Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

The Journal of clinical investigation, 1999-12, Vol.104 (11), p.1631-1639

1999

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Topical Application of A Novel Immunomodulatory Peptide, RDP58, Reduces Skin Inflammation in the Phorbol Ester-Induced Dermatitis Model

Journal of investigative dermatology, 2005-09, Vol.125 (3), p.473-481

2005

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Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury

Journal of the American Society of Nephrology, 2003-03, Vol.14 (3), p.745-754

2003

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Inhibition of Dendritic Cell Maturation and Function Is Independent of Heme Oxygenase 1 but Requires the Activation of STAT3

The Journal of immunology (1950), 2008-06, Vol.180 (12), p.7919-7930

2008

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Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway

Human gene therapy, 2002-07, Vol.13 (10), p.1189-1199

2002

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Sequence analysis of 0.5 Mb of the rabbit germline immunoglobulin heavy chain locus

Gene, 2004-04, Vol.330, p.49-59

2004

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Effects of BCL-2 over-expression on B cells in transgenic rats and rat hybridomas

International immunology, 2011-10, Vol.23 (10), p.625-636

2011

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Vaccination of Rabbits with an Alkylated Toxoid Rapidly Elicits Potent Neutralizing Antibodies against Botulinum Neurotoxin Serotype B

Clinical and Vaccine Immunology, 2010-06, Vol.17 (6), p.930-936

2010

Volltextzugriff (PDF)

Oral RDP58 Allows CPT-11 Dose Intensification for Enhanced Tumor Response by Decreasing Gastrointestinal Toxicity

Clinical cancer research, 2004-04, Vol.10 (8), p.2851-2859

2004

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Rational design and development of RDP58

Current pharmaceutical design, 2002-01, Vol.8 (24), p.2217

2002

Volltextzugriff (PDF)

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies

mAbs, 2019-05, Vol.11 (4), p.639-652

2019

Volltextzugriff (PDF)

Human Antibody Production in Transgenic Animals

Archivum Immunologiae et Therapiae Experimentalis, 2015-04, Vol.63 (2), p.101-108

2015

Volltextzugriff (PDF)

Strategies to Obtain Diverse and Specific Human Monoclonal Antibodies From Transgenic Animals

Transplantation, 2017-08, Vol.101 (8), p.1770

2017

Volltextzugriff (PDF)

A novel CD3xPSMA bispecific antibody for efficient T cell mediated killing of prostate tumor cells with minimal cytokine release

Journal of clinical oncology, 2019-03, Vol.37 (7_suppl), p.324-324

2019

Volltextzugriff (PDF)

Inhibition of Tumor Necrosis Factor mRNA Translation by a Rationally Designed Immunomodulatory Peptide

The Journal of biological chemistry, 2000-06, Vol.275 (22), p.17051-17057

2000

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Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

The mast cell-B cell axis in lung vascular remodeling and pulmonary hypertension

TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

Generation of gene-specific mutated rats using zinc-finger nucleases

Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity

Characterization of immunoglobulin heavy chain knockout rats

Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

Topical Application of A Novel Immunomodulatory Peptide, RDP58, Reduces Skin Inflammation in the Phorbol Ester-Induced Dermatitis Model

Gene transfer-induced local heme oxygenase-1 overexpression protects rat kidney transplants from ischemia/reperfusion injury

Inhibition of Dendritic Cell Maturation and Function Is Independent of Heme Oxygenase 1 but Requires the Activation of STAT3

Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway

Sequence analysis of 0.5 Mb of the rabbit germline immunoglobulin heavy chain locus

Effects of BCL-2 over-expression on B cells in transgenic rats and rat hybridomas

Vaccination of Rabbits with an Alkylated Toxoid Rapidly Elicits Potent Neutralizing Antibodies against Botulinum Neurotoxin Serotype B

Oral RDP58 Allows CPT-11 Dose Intensification for Enhanced Tumor Response by Decreasing Gastrointestinal Toxicity

Rational design and development of RDP58

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies

Human Antibody Production in Transgenic Animals

Strategies to Obtain Diverse and Specific Human Monoclonal Antibodies From Transgenic Animals

A novel CD3xPSMA bispecific antibody for efficient T cell mediated killing of prostate tumor cells with minimal cytokine release

Inhibition of Tumor Necrosis Factor mRNA Translation by a Rationally Designed Immunomodulatory Peptide

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