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CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells

Journal of virology, 2023-09, Vol.97 (9), p.e0092323-e0092323

2023

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Small molecule inhibitors of transcriptional cyclin-dependent kinases impose HIV-1 latency, presenting "block and lock" treatment strategies

Antimicrobial agents and chemotherapy, 2024-03, Vol.68 (3), p.e0107223-e0107223

2024

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Rapid Detection of SARS-CoV-2 Variants of Concern, Including B.1.1.28/P.1, British Columbia, Canada

Emerging infectious diseases, 2021-06, Vol.27 (6), p.1673-1676

2021

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Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008813-e1008813

2020

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HIV-1 variants are archived throughout infection and persist in the reservoir

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008378-e1008378

2020

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T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics

PLoS pathogens, 2020-12, Vol.16 (12), p.e1009177-e1009177

2020

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Influence of HLA-C Expression Level on HIV Control

Science (American Association for the Advancement of Science), 2013-04, Vol.340 (6128), p.87-91

2013

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Inhibition of the TRIM24 bromodomain reactivates latent HIV-1

Scientific reports, 2023-01, Vol.13 (1), p.556-15, Article 556

2023

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Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results

The Journal of infectious diseases, 2020-08, Vol.222 (6), p.899-902

2020

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HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)

Nature communications, 2021-01, Vol.12 (1), p.165-165, Article 165

2021

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HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

PloS one, 2009-08, Vol.4 (8), p.e6687-e6687

2009

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SARS-CoV-2 live virus neutralization after four COVID-19 vaccine doses in people with HIV receiving suppressive antiretroviral therapy

AIDS (London), 2023-04, Vol.37 (5), p.F11-F18

2023

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Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

PLoS medicine, 2008-05, Vol.5 (5), p.e100-e100

2008

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Older Adults Mount Less Durable Humoral Responses to Two Doses of COVID-19 mRNA Vaccine but Strong Initial Responses to a Third Dose

The Journal of infectious diseases, 2022-09, Vol.226 (6), p.983-994

2022

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Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults

The Journal of infectious diseases, 2022-04, Vol.225 (7), p.1129-1140

2022

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HIV-1 Vpu Mediates HLA-C Downregulation

Cell host & microbe, 2016-05, Vol.19 (5), p.686-695

2016

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Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002529-e1002529

2012

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HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy

PLoS pathogens, 2022-11, Vol.18 (11), p.e1010613-e1010613

2022

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HIV-1 adaptation to HLA: a window into virus–host immune interactions

Trends in microbiology (Regular ed.), 2015-04, Vol.23 (4), p.212-224

2015

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Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

PLoS medicine, 2015-04, Vol.12 (4), p.e1001810-e1001810

2015

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Operationalizing the One Health approach: the global governance challenges

Health policy and planning, 2013-10, Vol.28 (7), p.778-785

2013

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Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag

PLoS computational biology, 2008-11, Vol.4 (11), p.e1000225-e1000225

2008

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Serial infection with SARS-CoV-2 Omicron BA.1 and BA.2 following three-dose COVID-19 vaccination

Frontiers in immunology, 2022-09, Vol.13, p.947021-947021

2022

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Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8 + T cell immunity

Nature communications, 2022-10, Vol.13 (1), p.6473-6473, Article 6473

2022

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Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors

PloS one, 2015-04, Vol.10 (4), p.e0121099-e0121099

2015

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CDK8 inhibitors antagonize HIV-1 reactivation and promote provirus latency in T cells

Small molecule inhibitors of transcriptional cyclin-dependent kinases impose HIV-1 latency, presenting "block and lock" treatment strategies

Rapid Detection of SARS-CoV-2 Variants of Concern, Including B.1.1.28/P.1, British Columbia, Canada

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

HIV-1 variants are archived throughout infection and persist in the reservoir

T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics

Influence of HLA-C Expression Level on HIV Control

Inhibition of the TRIM24 bromodomain reactivates latent HIV-1

Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results

HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA)

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

SARS-CoV-2 live virus neutralization after four COVID-19 vaccine doses in people with HIV receiving suppressive antiretroviral therapy

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

Older Adults Mount Less Durable Humoral Responses to Two Doses of COVID-19 mRNA Vaccine but Strong Initial Responses to a Third Dose

Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults

HIV-1 Vpu Mediates HLA-C Downregulation

Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy

HIV-1 adaptation to HLA: a window into virus–host immune interactions

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

Operationalizing the One Health approach: the global governance challenges

Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag

Serial infection with SARS-CoV-2 Omicron BA.1 and BA.2 following three-dose COVID-19 vaccination

Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8 + T cell immunity

Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors

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